收费全文 | 38939篇 |
免费 | 3550篇 |
国内免费 | 3060篇 |
耳鼻咽喉 | 301篇 |
儿科学 | 348篇 |
妇产科学 | 322篇 |
基础医学 | 4094篇 |
口腔科学 | 616篇 |
临床医学 | 4420篇 |
内科学 | 5861篇 |
皮肤病学 | 377篇 |
神经病学 | 1720篇 |
特种医学 | 1479篇 |
外国民族医学 | 14篇 |
外科学 | 4086篇 |
综合类 | 8155篇 |
现状与发展 | 2篇 |
一般理论 | 3篇 |
预防医学 | 2857篇 |
眼科学 | 896篇 |
药学 | 4484篇 |
27篇 | |
中国医学 | 2277篇 |
肿瘤学 | 3210篇 |
2024年 | 124篇 |
2023年 | 534篇 |
2022年 | 1265篇 |
2021年 | 1626篇 |
2020年 | 1310篇 |
2019年 | 1172篇 |
2018年 | 1255篇 |
2017年 | 1140篇 |
2016年 | 1110篇 |
2015年 | 1567篇 |
2014年 | 2022篇 |
2013年 | 1900篇 |
2012年 | 2725篇 |
2011年 | 2836篇 |
2010年 | 1998篇 |
2009年 | 1716篇 |
2008年 | 2088篇 |
2007年 | 2171篇 |
2006年 | 2096篇 |
2005年 | 1827篇 |
2004年 | 1866篇 |
2003年 | 2157篇 |
2002年 | 1978篇 |
2001年 | 1670篇 |
2000年 | 1182篇 |
1999年 | 781篇 |
1998年 | 505篇 |
1997年 | 471篇 |
1996年 | 369篇 |
1995年 | 353篇 |
1994年 | 261篇 |
1993年 | 166篇 |
1992年 | 219篇 |
1991年 | 204篇 |
1990年 | 176篇 |
1989年 | 142篇 |
1988年 | 133篇 |
1987年 | 115篇 |
1986年 | 116篇 |
1985年 | 68篇 |
1984年 | 33篇 |
1983年 | 28篇 |
1982年 | 14篇 |
1981年 | 18篇 |
1980年 | 11篇 |
1979年 | 8篇 |
1978年 | 7篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1974年 | 2篇 |
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Objective
This study assessed the association between the timing of first epinephrine administration (EA) and the neurological outcomes following out-of-hospital cardiac arrests (OHCAs) with both initial shockable and non-shockable rhythms.Methods
This was a post-hoc analysis of a multicenter prospective cohort study (SOS-KANTO 2012), which registered OHCA patients in the Kanto region of Japan from January 2012 to March 2013. We included consecutive adult OHCA patients who received epinephrine. The primary result included 1-month favorable neurological outcomes defined as cerebral performance category (CPC) 1 or 2. Secondary results included 1-month survival and return of spontaneous circulation (ROSC) after arrival at the hospital. Multivariable logistic regression analysis determined the association between delay per minute of the time from call to first EA in both pre- or in-hospital settings and outcomes.Results
Of the 16,452 patients, 9344 were eligible for our analyses. In univariable analysis, the delay in EA was associated with decreased favorable neurological outcomes only when the initial rhythm was a non-shockable rhythm. In multivariable analyses, delay in EA was associated with decreased ROSC (adjusted odds ratio [OR] for one minute delay, 0.97; 95% confidence interval [CI], 0.96–0.98) and 1-month survival (adjusted OR, 0.95; 95% CI, 0.92–0.97) when the initial rhythm was a non-shockable rhythm, whereas during a shockable rhythm, delay in EA was not associated with decreased ROSC and 1-month survival.Conclusions
While assessing the effectiveness of epinephrine for OHCA, we should consider the time-limited effects of epinephrine. Additionally, consideration of early EA based on the pathophysiology is needed. 相似文献Research design and methods: A sample of 1139 reports received by the Shaanxi ADR Monitoring Center from January 2015 to December 2017 was selected. ADR report quality was evaluated using an ADR report quality evaluation system.
Results: None of the reports were rated as excellent and 1.40% (n = 16) as good. Report quality was better for new and serious reports than for general reports. Medical institutions generated higher quality reports than pharmaceutical manufacturers. Nurses generated higher quality reports than doctors, pharmacists, and other professionals. Reporters of different occupations showed significant differences in the quality of the indicators Reporting time limit, Intervention ADR time, ADR termination time, ADR intervention measures, Original disease, and Cause of medication (P = 0.000).
Conclusions: The ADR data quality was poor in western China, and of lower quality than reported data from previous research in other regions. Improvements in the quality and availability of ADR reports are urgently needed. 相似文献