全文获取类型
收费全文 | 6939篇 |
免费 | 630篇 |
国内免费 | 93篇 |
专业分类
耳鼻咽喉 | 74篇 |
儿科学 | 250篇 |
妇产科学 | 117篇 |
基础医学 | 517篇 |
口腔科学 | 125篇 |
临床医学 | 1236篇 |
内科学 | 1795篇 |
皮肤病学 | 243篇 |
神经病学 | 648篇 |
特种医学 | 196篇 |
外科学 | 1220篇 |
综合类 | 75篇 |
一般理论 | 6篇 |
预防医学 | 256篇 |
眼科学 | 196篇 |
药学 | 298篇 |
中国医学 | 20篇 |
肿瘤学 | 390篇 |
出版年
2023年 | 109篇 |
2022年 | 91篇 |
2021年 | 216篇 |
2020年 | 152篇 |
2019年 | 158篇 |
2018年 | 235篇 |
2017年 | 227篇 |
2016年 | 231篇 |
2015年 | 248篇 |
2014年 | 351篇 |
2013年 | 375篇 |
2012年 | 396篇 |
2011年 | 408篇 |
2010年 | 358篇 |
2009年 | 391篇 |
2008年 | 343篇 |
2007年 | 281篇 |
2006年 | 303篇 |
2005年 | 250篇 |
2004年 | 245篇 |
2003年 | 177篇 |
2002年 | 171篇 |
2001年 | 109篇 |
2000年 | 75篇 |
1999年 | 95篇 |
1998年 | 85篇 |
1997年 | 141篇 |
1996年 | 131篇 |
1995年 | 123篇 |
1994年 | 100篇 |
1993年 | 95篇 |
1992年 | 90篇 |
1991年 | 50篇 |
1990年 | 43篇 |
1989年 | 43篇 |
1988年 | 53篇 |
1987年 | 44篇 |
1986年 | 42篇 |
1985年 | 39篇 |
1984年 | 38篇 |
1983年 | 40篇 |
1982年 | 39篇 |
1980年 | 43篇 |
1979年 | 23篇 |
1978年 | 23篇 |
1974年 | 28篇 |
1973年 | 24篇 |
1960年 | 21篇 |
1955年 | 20篇 |
1954年 | 19篇 |
排序方式: 共有7662条查询结果,搜索用时 31 毫秒
1.
Maaike van Gerwen MD Naomi Alpert MS Raja Flores MD Emanuela Taioli MD PhD 《American journal of industrial medicine》2020,63(2):115-120
The association between asbestos exposure, mainly in occupational settings, and malignant mesothelioma has been well established; this has prompted several countries to establish mesothelioma epidemiologic surveillance programs often at the request of national agencies. This review compares currently existing mesothelioma registries worldwide to develop a concept model for a US real-time case capture mesothelioma registry. Five countries were identified with a mesothelioma specific registry, including Italy, France, UK, Australia, and South Korea. All, except the UK, used interviews to collect exposure data. Linkage with the national death index was available or was in future plans for all registries. The registries have limited information on treatment, quality of life, and other patient-centered outcomes such as symptoms and pain management. To thoroughly collect exposure data, “real-time” enrollment is preferable; to maximize the capture of mesothelioma cases, optimal coverage, and a simplified consent process are needed. 相似文献
2.
3.
Femoral access‐related complications during percutaneous transcatheter aortic valve implantation comparing single versus double Prostar XL device closure
下载免费PDF全文
![点击此处可从《Catheterization and cardiovascular interventions》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
5.
6.
HOCK LEONG EE MBBS MRCP CHEE LEOK GOH MBBS FRCP KHOO ES-Y. CHAN PHD POR ANG MBBS MRCP 《Dermatologic surgery》2006,32(1):34-40
BACKGROUND: Acquired bilateral nevus of Ota-like macules (Hori's nevus) is a common dyschromatosis among Asian women. Q-switched lasers have been used successfully as a treatment modality. OBJECTIVE: The purpose of this study was to compare the efficacy of using the Q-switched 532 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser followed by the 1,064 nm laser versus the Q-switched 1,064 nm Nd:YAG laser alone in the treatment of Hori's nevus. METHODS: This is a prospective left-right comparative study. Ten women with bilateral Hori's nevus were recruited and treated with a combination of the Q-switched 532 and 1,064 nm Nd:YAG lasers on the right cheek and the Q-switched 1,064 nm Nd:YAG laser alone on the left cheek. Only one laser treatment session was performed. The degree of pigmentation was objectively recorded with a mexameter. Subjective assessment was made by both patients and two blinded, nontreating dermatologists. RESULTS: At 6 months, there was a statistically significant difference (p = .009) of 35.10 points using objective mexameter measurements between the two sides, favoring the side treated with a combination of 532 and 1,064 nm laser treatment. Subjective grading by the patients and blinded dermatologists also confirmed that combination therapy was more successful after one treatment. Although combination treatment had a higher incidence of mild postinflammatory changes, this disappeared within 2 months. CONCLUSIONS: Concurrent use of the Q-switched 532 nm Nd:YAG laser in combination with the 1,064 nm laser is more effective in pigment clearance than the Q-switched 1,064 nm Nd:YAG laser alone for Hori's nevi. 相似文献
7.
Dr. Arthur A. Dunk MRCP Natasha Kyprianou MSc Peter Davies PhD Howard C. Thomas PhD FRCP 《Digestive diseases and sciences》1988,33(4):472-476
Castrated or sham-operated male athymic mice were inoculated with cells from the human hepatocellular carcinoma cell line PLC/PRF/5. There were no significant differences between the two groups with respect to the number of animals developing tumors, the time to tumor development, or the subsequent rate of increase in either tumor base area or mouse serum alpha-fetoprotein concentration. Androgen receptors were assayed in nuclei obtained from three separate liver cancer cell lines and from normal adult human liver. Similar concentrations, ranging from 235 to 550 fmol/mg DNA, of nuclear androgen receptors were detected in all tissues. Low percentages of androgen receptors were retained on DNA-cellulose. Although the presence of receptors implies the potential for metabolic effects of androgens in normal and malignant liver, our in vivostudies suggest that castration does not alter significantly the growth of liver cancer xenografts in athymic mice. 相似文献
8.
Perianal mucinous adenocarcinoma is a rare tumour which may be associated with long‐standing chronic perianal sepsis. Early diagnosis is challenging and is based on a high index of clinical suspicion and specific histological features. Definitive treatment is surgical, in the form of an abdomino‐perineal resection. We hereby describe a case of a perianal mucinous adenocarcinoma arising from long‐standing recurrent perianal fistula and complement this with a brief review of the literature pertaining in particular to the management of this condition. 相似文献
9.
Raja Kandaswamy J. Keith Melancon Ty Dunn Miguel Tan Vincent Casingal Abhinav Humar William D. Payne Rainer W. G. Gruessner David L. Dunn John S. Najarian David E. R. Sutherland Kristen J. Gillingham Arthur J. Matas 《American journal of transplantation》2005,5(6):1529-1536
We compared three maintenance immunosuppressive regimens in a rapid discontinuation of prednisone protocol. From March 1, 2001, through December 31, 2003, 239 first and second kidney transplant recipients (166 LD; 73 DD) were randomized. All recipients were treated with Thymoglobulin; all received steroids intraoperatively and for 5 days postoperatively. Randomization was to cyclosporine-mycophenolate mofetil (n = 85); high-level tacrolimus (TAC) (8-12 ng/mL)-low-level sirolimus (SRL) (3-7 ng/mL) (n = 72); or low-level TAC (3-7 ng/mL)-high-level SRL (8-12 ng/mL) (n = 82). We found no difference at 24 months between groups in patient, graft, death-censored graft, or acute rejection-free graft survival, or in kidney function. Wound complications were more common in SRL-treated recipients (p = 0.02); we found no other differences between groups in complication rates. Our data suggest that excellent patient and graft survival and low rejection rates can be obtained using a variety of maintenance protocols without prednisone. 相似文献
10.
M Vijaya Lakshmi MRCP G V Sridharan MRCP D Butterworth MRCP 《International journal of clinical practice》1993,47(3):164-165
Gallstones are common and their incidence increases with age.1 Fifty per cent of these stones are in the common bile duct (CBD) in the elderly.2 Most of them are silent but with time there is an increasing chance of developing symptoms which are more likely to be serious in the elderly.3 Failure to relieve mechanical obstruction of bile flow may lead to secondary biliary cirrhosis.4 It has been estimated that on average secondary biliary cirrhosis develops some seven years after the onset of obstruction from a stricture, four and half years after gallstone obstruction and 10 months after the onset of malignant stricture.5 The characteristic features are the pathological findings of portal-portal linkages, with a pattern of monolobular cirrhosis and the preservation of normal vascular relationships.6 Secondary biliary cirrhosis may lead to hepatic insufficiency and portal hypertension with the resultant complications, such as bleeding oesophageal varices, hypersplenism with pancytopenia, ascites and encephalopathy. We describe a patient in whom the diagnosis was not suspected until laparotomy and confirmed only at autopsy. 相似文献