全文获取类型
收费全文 | 18230篇 |
免费 | 733篇 |
国内免费 | 112篇 |
专业分类
耳鼻咽喉 | 214篇 |
儿科学 | 293篇 |
妇产科学 | 186篇 |
基础医学 | 2127篇 |
口腔科学 | 459篇 |
临床医学 | 1213篇 |
内科学 | 4404篇 |
皮肤病学 | 294篇 |
神经病学 | 1709篇 |
特种医学 | 686篇 |
外科学 | 2982篇 |
综合类 | 77篇 |
一般理论 | 1篇 |
预防医学 | 553篇 |
眼科学 | 663篇 |
药学 | 1355篇 |
中国医学 | 39篇 |
肿瘤学 | 1820篇 |
出版年
2023年 | 85篇 |
2022年 | 178篇 |
2021年 | 296篇 |
2020年 | 142篇 |
2019年 | 213篇 |
2018年 | 317篇 |
2017年 | 254篇 |
2016年 | 351篇 |
2015年 | 335篇 |
2014年 | 413篇 |
2013年 | 513篇 |
2012年 | 849篇 |
2011年 | 964篇 |
2010年 | 598篇 |
2009年 | 489篇 |
2008年 | 913篇 |
2007年 | 1009篇 |
2006年 | 1039篇 |
2005年 | 1036篇 |
2004年 | 1022篇 |
2003年 | 942篇 |
2002年 | 990篇 |
2001年 | 480篇 |
2000年 | 412篇 |
1999年 | 452篇 |
1998年 | 259篇 |
1997年 | 241篇 |
1996年 | 207篇 |
1995年 | 173篇 |
1994年 | 162篇 |
1993年 | 175篇 |
1992年 | 329篇 |
1991年 | 259篇 |
1990年 | 236篇 |
1989年 | 255篇 |
1988年 | 222篇 |
1987年 | 247篇 |
1986年 | 220篇 |
1985年 | 213篇 |
1984年 | 170篇 |
1983年 | 144篇 |
1982年 | 80篇 |
1981年 | 69篇 |
1979年 | 141篇 |
1978年 | 74篇 |
1977年 | 74篇 |
1975年 | 68篇 |
1974年 | 77篇 |
1970年 | 77篇 |
1968年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Satoshi Iyama Yasuo Takahashi Naoaki Shintani Koshi Fujikawa Syunichi Ohkubo Yasushi Sato Tsutomu Sato Yasuhiro Sato Keisuke Ohnuma Yoshiro Niitsu 《Nihon Shokakibyo Gakkai zasshi》2006,103(10):1163-1168
We report a case of biliary cystadenocarcinoma which recurred 41 months postoperatively. A 60-year-old woman was admitted for further examination of multiple metastatic tumors and a large amount of ascites. Systemic administration of 5FU and CDDP caused her CEA level to decrease gradually and abdominal computed tomography revealed considerable reduction of the metastatic tumors and ascites. Since her general condition had improved, chemotherapy was continued in the outpatient clinic. 相似文献
2.
3.
A case of Ullrich disease was presented. The patient was a 3-year-old girl with torticollis, generalized muscle weakness and acroatonia since birth. High-arched palate, protruded calcaneus, and mild contracture of proximal joints were also recognized. Intellectual development was normal. Serum level of CPK was slightly increased. In histological and histochemical examinations of quadriceps femoris muscle, proliferated connective tissue, marked variation in the muscle fiber diameter, and a lot of degenerated and regenerated fibers were recognized. Minimal injury easily causes subcutaneous hemorrhage, but no abnormality was found in the structure of collagen. 相似文献
4.
Yasuo Suzuki 《Journal of neuro-ophthalmology》2007,27(2):138-142
Kenji Ohtsuka, MD and his colleagues at the Sapporo Medical University have investigated the central organization of the near response with anatomical and neurophysiologic studies in cats. Based on their data and clinical observations, they proposed that the rostral pole of the superior colliculus has a critical role in the control of accommodation, vergence, and fixation. Although the central pathways have yet to be fully worked out, the contributions of Dr. Ohtsuka, who died in 2005, have laid an important foundation in the understanding of these functions. 相似文献
5.
6.
PURPOSE: The aim of this study is (1) to develop a new method of risk classification for clinically localized prostate cancer; (2) to examine it in terms of compatibility with existing data such as nomograms; and (3) to compare it with existing risk-grouping methods. MATERIAL AND METHODS: The new grading system introduced here consists of three factors. The first is a prostate-specific antigen (PSA) of 4.1-10.0 ng/ml (score 0), 10.1-20.0 ng/ml (score 1), and >20.0 ng/ml (score 2). The second is a Gleason score (GS) of 6 (score 0), 7 (score 1), and 8-10 (score 2). The third is T classifications (UICC 2002) of T1c-T2a (score 0), T2b-T2c (score 1), and T3a (score 2). The sum of the three scores was named Prostate Risk Index (PRIX). Then, the compatibility of PRIX with the Partin Table, Kattan Nomogram, and Roach's formula was examined. At the same time, PRIX was compared with D'Amico, the National Comprehensive Cancer Network (NCCN), and Seattle classifications. RESULTS: PRIX 0 corresponded to 1-2% of pathologic lymph node involvement (pLN+) according to the Partin Table; PRIX 1 to 3-4%; PRIX 2 to 7-10%; PRIX 3 to 14-18%; PRIX 4 to 24-29%; PRIX 5 to 32-37%; and PRIX 6 to 42%. PRIX well separated the risks with relatively narrow ranges of probability, while D'Amico, NCCN, and Seattle classifications generally gave wide ranges especially for high-risk groups, both in the Partin Table and Kattan Nomogram. Roach's formula sometimes overestimated the risk compared to the Partin Table. CONCLUSION: PRIX fully corresponded to the Partin Table in terms of pLN+, and corresponded to the other nomograms better than any existing risk-grouping method. PRIX may thus function as a prognostic factor or contribute to patient selection in clinically localized prostate cancer. 相似文献
7.
Christabel E. Fowler Elia Beniash Yasuo Yamakoshi James P. Simmer Henry C. Margolis 《European journal of oral sciences》2006,114(S1):297-303
An amorphous silica mineralization technique was used to produce inorganic/protein composites to elucidate the structure and mechanism of formation of amelogenin assemblies, which may play an important role in regulating enamel structure during the initial stages of amelogenesis. Full-length recombinant amelogenins from mouse (rM179) and pig (rP172) were investigated along with key degradation products (rM166 and native P148) lacking the hydrophilic C terminus found in parent molecules. The resulting products were examined using transmission electron microscopy and/or small-angle X-ray scattering. Using protein concentrations of 0.1–3 mg ml−1 , large monodisperse spheres of remarkably similar mean diameters were observed using rM179 (124 ± 4 nm) and rP172 (126 ± 7 nm). These spheres also exhibited 'internal structure', comprising nearly spherical monodisperse particles of ≈ 20 nm in diameter. In the presence of rM166, P148, and bovine serum albumin (control), large unstructured and randomly shaped particles (250–1000 nm) were observed. Without added protein, large dense spherical particles of silica (mean ≈ 500 nm) lacking internal structure were produced. These findings demonstrate that full-length amelogenins have the ability to form higher-order structures, whereas amelogenins that lack the hydrophilic C terminus do not. The results also suggest that full-length amelogenin can guide the formation of organized mineralized structures through co-operative interactions between assembling protein and forming mineral. 相似文献
8.
Madoka Minoguchi Nobuyuki Yanagawa Chisato Ishikawa Junpei Sasajima Mitsuru Goto Miho Okamoto Yoshinori Saito Masanori Murakami Yutaka Orii Toru Yaosaka 《Nihon Shokakibyo Gakkai zasshi》2007,104(7):1082-1087
Pancreatic metastasis of malignant melanoma is rarely diagnosed while the patient is alive. We report a case of metastatic melanoma of the pancreas in a 35-year-old woman presenting with a solid mass of the pancreas. Her past medical history included a radical hysterectomy 2 years previously for malignant melanoma of the vagina. Twelve months later, lung metastasis was also resected. EUS-guided fine needle aspiration (EUS-FNA) identified that the pancreatic tumor was histologically and immunohistochemically identical to the surgical specimen of her lung neoplasm. Imaging studies including US, CT, and MRI have limited value to distinguish the tumors from primary ductal adenocarcinoma. EUS-FNA can provide tissue diagnosis from pancreatic masses, specifically when other modalities have failed. 相似文献
9.
10.