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排序方式: 共有96条查询结果,搜索用时 15 毫秒
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Metabolite changes with age measured by proton magnetic resonance spectroscopy in normal subjects 总被引:1,自引:0,他引:1
HIROSHI FUKUZAKO md TOMO HASHIGUCHI md YASUHIRO SAKAMOTO md HISATAKA OKAMURA md WATARU DOI md KAORU TAKENOUCHI md MORIKUNI TAKIGAWA md 《Psychiatry and clinical neurosciences》1997,51(4):261-263
Abstract To determine whether there are metabolite changes in the left medial temporal and frontal lobes with aging, we performed proton magnetic resonance spectroscopy in 36 normal subjects. The N-acetylaspartate/creatine-phosphocreatine ratio in the medial temporal lobe tended to be decreased in subjects over 60 years of age. The ratio decrease in the frontal lobe related to aging was lower than that in the medial temporal lobe. There were no significant differences in the metabolite ratios between males and females. These findings suggest that structures in the medial temporal lobe may be more susceptible to neuronal dysfunction associated with aging than those in the frontal lobe. 相似文献
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YASUHIRO KAWACHI M.D. MICHIKO IKEGAMI M.D. TAKAKO TAKASE M.D. FUJIO OTSUKA M.D. 《Pediatric dermatology》2010,27(5):527-528
Abstract: We report clinical findings in a 12‐year‐old girl with long‐term recurrent and disseminated multiple eruptions of tinea faciei and tinea corporis, which persisted for 10 years. Mycological examination revealed the dermatophyte Trichophyton tonsurans in both scale samples from the body lesions and in brushing samples from her asymptomatic scalp, suggesting that she was an asymptomatic dermatophyte carrier on the scalp, and autoinoculation of the dermatophyte was responsible for the recurrent and disseminated tinea faciei/corporis. 相似文献
5.
SUGURU MATSUOKA EMMANUEL EH ANTONIOU KAZUHIRO MORI YASUNOBU HAYABUCHI YASUHIRO KURODA 《Pediatrics international》1995,37(4):514-517
The first case of a patient with interrupted inferior vena cava, four post-renal veins and an azygoshemiazygos continuation is presented. The complicated anomalies were omphalocele and atrial septal defect. Cine-magnetic resonance imaging and cardiac catheterization showed an anomalous retroaortic left innominate vein, azygos-hemiazygos continuation in the prerenal portion, arch formed renal vein in the renal portion and four embryonic vessels in the post-renal portion. Combination of these anomalies in the major venous system suggested that the inferior vena cava had failed to form and that the bilateral embryonic venous system, postcardinal and supracardinal veins persisted to be the systemic venous channels. 相似文献
6.
SUGURU MATSUOKA HIROSHI AKITA YOSHIO TAKAHASHI ATSUKO NISHIOKA YASUHIRO KURODA 《Pediatrics international》1993,35(1):27-31
The present study examined chronotropic dysfunction and the role of vagotony in congenital long QT syndrome, sinus node function and the effects of parasympathetic blockade. Six patients with congenital long QT syndrome were studied. The four males and two females, aged 1–15 years, had episodes of syncope and malignant ventricular arrhythmias. Congenital long QT syndrome was defined as a corrected QT interval greater than 0.45 s, T wave alternans and the age at diagnosis. The sinus heart rate measured from a 24 h electrocardiograph was abnormally low (< 50 min) in three patients (1, 4 and 5 years old) and did not increase sufficiently with the administration of atropine in five of the six patients with congenital long QT syndrome. From intracardiac electrophysiological studies, the corrected sinus node recovery time was prolonged in three patients and the total sinoatrial conduction time was prolonged in two patients. In most patients who had an abnormally long sinoatrial conduction time and corrected sinus node recovery time, these values returned to normal following atropine administration. In one patient, the corrected sinus node recovery time was prolonged paradoxically by atropine. Sinus node dysfunction in congenital long QT syndrome was affected by vagotony associated with a right sympathetic nerve system abnormality. 相似文献
7.
SUGURU MATSUOKA KATSUNORI TATARA YURI USIROGUCHI MASAHIRO KUBO HIROSHI AKITA YASUHIRO KURODA 《Pediatrics international》1993,35(6):508-512
The purpose of this study was to determine whether pulmonary hemodynamic abnormalities relate to manifestations of allergic asthma. In 448 patients with congenital heart disease the relationships between asthma and age or pulmonary arterial blood (PA) flow were studied. Asthma (allergic and non-allergic) was more common in 39 (19%) of 201 patients with high PA flow, compared with the incidence in those with normal PA flow (6/117, 5%; P < 0.001) and reduced PA flow (1/130, 1%; P < 0.05). In the high PA flow group, the frequency of asthma declined significantly (P < 0.01) with age, from 25–26% in the 6 month-5 year patient group to 5% in the 6–12 year old patients. The frequency of asthma, including allergic type, was significantly (P < 0.01) greater in patients with pulmonary hypertension (15/24, 63%) than in those without (10/77, 13%) at the age of 6 months to 1 year. Asthma in the high PA flow group was associated with other allergic diseases in 30 (77%) of 39 patients, including food allergy in nine (23%), atopic dermatitis in 14 (36%), allergic rhinitis in seven (18%) and abnormally high total IgE levels in 14 (36%). These findings suggest that high pulmonary flow or pulmonary hypertension enhances the manifestation of allergic disease, particularly asthma. 相似文献
8.
Spectral analysis of changes in electroencephalographic activity after the chewing of gum 总被引:2,自引:1,他引:1
YASUHIRO MASUMOTO DDS TAKANOBU MORINUSHI DDS PhD HIROTOKI KAWASAKI BSC MORIKUNI TAKIGAWA MD 《Psychiatry and clinical neurosciences》1998,52(6):587-592
Abstract The present study aimed to examine the psychosomatic effect in the chewing of marketed gum using eletroencephalogram (EEG) as an index. The EEG were taken in two sets: (i) a resting period before chewing (control recording) and a resting record (post-resting recording) for examining reproducibility; and (ii) a control recording and resting period after gum-chewing for 3 min (post-chewing recording). The ratio of each frequency band to the total frequency power, the mean frequency of the alpha band and laterality of the frequency power was calculated. In the examination of the reproducibility, no statistically significant differences were observed between control recording and post-resting recording in all indices. In the reflection of EEG after gum-chewing, there were no significant differences between control recording and the post-chewing recording. However, a significant interaction was observed among these indices by analysis of variance. In addition, the alpha power in the post-chewing recording was significantly higher than that in the control recording at almost all the positions. In conclusion, the intra-individual reproducibility of EEG was confirmed in the recording method. Furthermore, it was suggested that a significant interaction and a rising trend of the mean frequency of the alpha band after gum-chewing reflected 'arousal' psychosomatic responses by the chewing of marketed gum. 相似文献
9.
ALEC VAHANIAN M.D. BERNARD IUNG M.D. BERTRAND CORMIER M.D. YASUHIRO MAKITA M.D. PHILIPPE LUXEREAU M.D. 《Journal of interventional cardiology》2000,13(4):281-285
We are now able to analyze follow-up data up to 10 years after percutaneous mitral commissurotomy (PMC). In clinical terms, several large single-center series confirm the late efficacy of the procedure in a large population, comprising a variety of patient subsets. When the immediate results are unsatisfactory, prognosis is poor and surgery should be carried out when the clinical conditions allow it. Conversely, if PMC is initially successful, the clinical results are excellent and late deterioration is mainly related to restenosis. Preliminary series have shown that repeat balloon commissurotomy may be performed successfully in such patients. The prediction of late results after balloon commissurotomy is multifactorial and based on clinical parameters, valve anatomy, and the immediate results of the procedure. Randomized studies have shown that the long-term results of balloon commissurotomy are as good as those of surgery in patients with favorable characteristics. In the others, there has been no comparative study and patient selection should take into account the multifactorial nature of the prediction of late results. Overall, these good long-term results have led to an increased use of balloon commissurotomy in the treatment of patients with mitral stenosis. 相似文献
10.
YOSHIAKI KANEKO M.D. Ph .D. TADASHI NAKAJIMA M.D. Ph .D. AKIHIRO SAITO M.D. TADANOBU IRIE M.D. MASAKI OTA M.D. TOSHIMITSU KATO M.D. TAKAFUMI IIJIMA M.D. MAMORU MANITA M.D. Ph .D. TOSHIO ITO M.D. MASAHIRO AKIYAMA M.D. Ph .D. YASUHIRO TANIGUCHI M.D. MASAHIKO KURABAYASHI M.D. Ph .D. 《Pacing and clinical electrophysiology : PACE》2009,32(S1):S72-S75
Background: The purpose of this study was to identify the His-bundle (HB) versus right bundle branch (RBB) during electrophysiologic studies, using the V3 phenomenon, and to compare the timing of HB versus RBB potentials of sinus cycles (His-ventricular [H-V] interval).
Methods: The study enrolled 16 patients without structural heart disease, who underwent electrophysiologic studies during which the H-V interval was within normal limits and the V3 phenomenon was induced during recordings of the HB and the RBB potentials by a multi-electrode catheter. The recording site of the earliest HB potential just before the V3 phenomenon was defined as the branching portion of His bundle (HBBP), the site immediately proximal to the HBBP as the HB, and the site immediately distal to the HBBP as the RBB.
Results: The HBBP was identified in all patients. In all cases but one patient, the H-V interval measured at the HB adjacent to the HBBP was ≥35 ms. However, in 12 patients, the H-V interval measured at the RBB adjacent to the HBBP was also ≥35 ms.
Conclusions: The electrophysiologic identification of HB versus RBB by simultaneous recordings of HB and RBB potentials during induction of the V3 phenomenon was feasible. When the discrimination between HB and RBB was based on the measurement of the H-V interval, the proximal portion of the RBB was frequently misidentified as the HB. 相似文献
Methods: The study enrolled 16 patients without structural heart disease, who underwent electrophysiologic studies during which the H-V interval was within normal limits and the V3 phenomenon was induced during recordings of the HB and the RBB potentials by a multi-electrode catheter. The recording site of the earliest HB potential just before the V3 phenomenon was defined as the branching portion of His bundle (HBBP), the site immediately proximal to the HBBP as the HB, and the site immediately distal to the HBBP as the RBB.
Results: The HBBP was identified in all patients. In all cases but one patient, the H-V interval measured at the HB adjacent to the HBBP was ≥35 ms. However, in 12 patients, the H-V interval measured at the RBB adjacent to the HBBP was also ≥35 ms.
Conclusions: The electrophysiologic identification of HB versus RBB by simultaneous recordings of HB and RBB potentials during induction of the V3 phenomenon was feasible. When the discrimination between HB and RBB was based on the measurement of the H-V interval, the proximal portion of the RBB was frequently misidentified as the HB. 相似文献