全文获取类型
收费全文 | 11040篇 |
免费 | 876篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 87篇 |
儿科学 | 385篇 |
妇产科学 | 375篇 |
基础医学 | 1599篇 |
口腔科学 | 162篇 |
临床医学 | 1375篇 |
内科学 | 2151篇 |
皮肤病学 | 171篇 |
神经病学 | 1424篇 |
特种医学 | 146篇 |
外科学 | 911篇 |
综合类 | 113篇 |
一般理论 | 18篇 |
预防医学 | 1403篇 |
眼科学 | 76篇 |
药学 | 890篇 |
中国医学 | 18篇 |
肿瘤学 | 635篇 |
出版年
2023年 | 62篇 |
2022年 | 107篇 |
2021年 | 258篇 |
2020年 | 168篇 |
2019年 | 268篇 |
2018年 | 265篇 |
2017年 | 191篇 |
2016年 | 221篇 |
2015年 | 267篇 |
2014年 | 352篇 |
2013年 | 546篇 |
2012年 | 774篇 |
2011年 | 761篇 |
2010年 | 431篇 |
2009年 | 353篇 |
2008年 | 591篇 |
2007年 | 688篇 |
2006年 | 627篇 |
2005年 | 611篇 |
2004年 | 599篇 |
2003年 | 569篇 |
2002年 | 514篇 |
2001年 | 201篇 |
2000年 | 150篇 |
1999年 | 157篇 |
1998年 | 140篇 |
1997年 | 112篇 |
1996年 | 115篇 |
1995年 | 97篇 |
1994年 | 69篇 |
1993年 | 89篇 |
1992年 | 110篇 |
1991年 | 104篇 |
1990年 | 113篇 |
1989年 | 93篇 |
1988年 | 89篇 |
1987年 | 77篇 |
1986年 | 71篇 |
1985年 | 66篇 |
1984年 | 83篇 |
1983年 | 46篇 |
1982年 | 64篇 |
1981年 | 73篇 |
1980年 | 38篇 |
1979年 | 52篇 |
1978年 | 44篇 |
1977年 | 47篇 |
1976年 | 44篇 |
1975年 | 35篇 |
1974年 | 37篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Rizzo Manglio Miguel Bluthgen Mara Virginia Recondo Gonzalo Naveira Martin Perfetti Aldo Rizzi Florencia Kuzminin Alejandro Faura Victoria Cerini Matas Videla Alejandro Silva Carlos Lupinacci Lorena Minatta Nicols 《International journal of clinical oncology / Japan Society of Clinical Oncology》2021,26(6):1057-1064
International Journal of Clinical Oncology - Immune-checkpoint inhibitors (ICIs) are standard treatments for metastatic non-small cell lung cancer (NSCLC). Patients with poor performance status... 相似文献
2.
Caroline E. Sloan Judy Zhong Dinushika Mohottige Rasheeda Hall Clarissa J. Diamantidis Leight E. Boulware Virginia Wang 《Seminars in dialysis》2020,33(6):440-448
Caring for patients with end-stage kidney disease (ESKD) in the United States is challenging, due in part to the complex epidemiology of the disease's progression as well as the ways in which care is delivered. As CKD progresses toward ESKD, the number of comorbidities increases and care involves multiple healthcare providers from multiple subspecialties. This occurs in the context of a fragmented US healthcare delivery system that is traditionally siloed by provider specialty, organization, as well as systems of payment and administration. This article describes the role of care fragmentation in the delivery of optimal ESKD care and identifies research gaps in the evidence across the continuum of care. We then consider the impact of care fragmentation on ESKD care from the patient and health system perspectives and explore opportunities for system-level interventions aimed at improving care for patients with ESKD. 相似文献
3.
4.
5.
6.
7.
Confounders contributing to the reported associations of coffee or caffeine with disease 总被引:2,自引:0,他引:2
G B Schreiber M Robins C E Maffeo M N Masters A P Bond D Morganstein 《Preventive medicine》1988,17(3):295-309
The role of caffeine or coffee in causing or promoting the incidence of serious disease is equivocal. Two design factors may account for the discrepancies in reported findings on the effects of coffee drinking: (a) imprecision of measurement and (b) confounding variables. A study of 2,714 white U.S. adults disclosed that, of 32 risk factors analyzed by linear and logistic regression, only sex and cigarette smoking were found to be important potential confounders of caffeine and coffee intake. Partial R2 values of the other 30 risk factors were relatively small and were inconsistent for each sex. It is unlikely that any of these factors could explain any of the reported associations between caffeine or coffee consumption and certain diseases. However, certain weak associations with caffeine or coffee intake should be included in the study design when they are known to be risk factors of a disease under investigation. These factors for men are dietary fat intake, vitamin C intake, and body mass index; and for women are vitamin use, alcohol intake, stress, and perceived health status. 相似文献
8.
M Parry-Billings B Leighton G D Dimitriadis J Bond E A Newsholme 《Biochemical pharmacology》1990,40(5):1145-1148
The effects of physiological and pathological concentrations of glucocorticoids were investigated using the glucocorticoid antagonist RU486 and the synthetic glucocorticoid dexamethasone, respectively. The effects of these treatments on the concentrations of glutamine and other amino acids in skeletal muscle and plasma and on the rates of release of glutamine and alanine from incubated preparations of skeletal muscle of the rat were investigated. Dexamethasone treatment increased the concentration of glutamine and the rate of release of this amino acid from incubated soleus muscle preparations. This treatment decreased the concentration of glutamine in both gastrocnemius and EDL muscles, but was without effect on the rate of glutamine release from EDL muscles. In contrast, administration of the glucocorticoid antagonist RU486 decreased the rate of glutamine release from muscle. It is concluded that glucocorticoids have marked effects on the metabolism of glutamine by skeletal muscle per se and that these hormones may be important in the control of the rate of glutamine release from muscle in both physiological and pathological conditions. 相似文献
9.
Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group 总被引:10,自引:0,他引:10
D H O'Leary J F Polak S K Wolfson M G Bond W Bommer S Sheth B M Psaty A R Sharrett T A Manolio 《Stroke; a journal of cerebral circulation》1991,22(9):1155-1163
Carotid sonography is being performed on more than 5,000 participants in the Cardiovascular Health Study, a prospective, multicenter study of cardiovascular disease in men and women aged 65 years and older. The sonographic methods used to examine and measure the extracranial carotid arteries are described. Initial validation studies were performed on 61 subjects with a mean age of 68.6 years. Analysis of within- and between-sonographer differences and between-reader differences were performed for selected variables. In general, the mean absolute differences for within- and between-sonographer comparisons were small, with even less variability between readers. Variability was less for the common carotid artery than for the internal carotid artery. These data suggest that carotid sonography is a reliable and reproducible method for use in the study of carotid atherosclerosis in population studies. 相似文献
10.
G R Bond 《New directions for mental health services》1991,(52):65-80
The author reviews recent research findings examining variations in an assertive outreach model. Mental health system and client characteristics that have influenced program implementation are discussed. 相似文献