全文获取类型
收费全文 | 3075篇 |
免费 | 256篇 |
国内免费 | 20篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 152篇 |
妇产科学 | 71篇 |
基础医学 | 356篇 |
口腔科学 | 96篇 |
临床医学 | 278篇 |
内科学 | 658篇 |
皮肤病学 | 166篇 |
神经病学 | 281篇 |
特种医学 | 293篇 |
外科学 | 334篇 |
综合类 | 44篇 |
一般理论 | 1篇 |
预防医学 | 169篇 |
眼科学 | 77篇 |
药学 | 153篇 |
1篇 | |
中国医学 | 1篇 |
肿瘤学 | 206篇 |
出版年
2023年 | 12篇 |
2022年 | 22篇 |
2021年 | 62篇 |
2020年 | 45篇 |
2019年 | 87篇 |
2018年 | 90篇 |
2017年 | 52篇 |
2016年 | 66篇 |
2015年 | 69篇 |
2014年 | 87篇 |
2013年 | 110篇 |
2012年 | 119篇 |
2011年 | 128篇 |
2010年 | 120篇 |
2009年 | 111篇 |
2008年 | 138篇 |
2007年 | 124篇 |
2006年 | 132篇 |
2005年 | 119篇 |
2004年 | 96篇 |
2003年 | 99篇 |
2002年 | 96篇 |
2001年 | 71篇 |
2000年 | 100篇 |
1999年 | 76篇 |
1998年 | 102篇 |
1997年 | 98篇 |
1996年 | 78篇 |
1995年 | 70篇 |
1994年 | 46篇 |
1993年 | 58篇 |
1992年 | 41篇 |
1991年 | 55篇 |
1990年 | 35篇 |
1989年 | 71篇 |
1988年 | 53篇 |
1987年 | 44篇 |
1986年 | 43篇 |
1985年 | 37篇 |
1984年 | 28篇 |
1983年 | 22篇 |
1982年 | 23篇 |
1981年 | 22篇 |
1980年 | 27篇 |
1979年 | 12篇 |
1978年 | 21篇 |
1977年 | 16篇 |
1976年 | 19篇 |
1975年 | 21篇 |
1973年 | 17篇 |
排序方式: 共有3351条查询结果,搜索用时 15 毫秒
1.
2.
3.
Luisa Rocha Manola Cuellar-Herrera Marcos Velasco Francisco Velasco Ana-Luisa Velasco Fiacro Jiménez Sandra Orozco-Suarez Anna Borsodi 《Seizure》2007,16(7):645-652
Opioid receptor binding was evaluated in parahippocampal cortex (PHC) obtained from patients with intractable mesial temporal lobe epilepsy (MTLE) with and without subacute high frequency electrical stimulation (HFS) in this brain area. Mu, delta and nociceptin receptor binding was determined by autoradiography in PHC of five patients (ESAE group) with MTLE history of 14.8 +/- 2.5 years and seizure frequency of 11 +/- 2.9 per month, two of them (40%) with mesial sclerosis. This group demonstrated antiepileptic effects following subacute HFS (130 Hz, 450 micros, 200-400 microA), applied continuously during 16-20 days in PHC. Values were compared with those obtained from patients with severe MTLE (history of 21.7 +/- 2.8 years and seizure frequency of 28.2 +/- 14 per month) in whom electrical stimulation did not induce antiepileptic effects (ESWAE group, n = 4), patients with MTLE in whom no electrical stimulation was applied (MTLE group, n = 4) and autopsy material acquired from subjects without epilepsy (n = 4 obtained from three subjects). Enhanced 3H-DAMGO (MTLE, 755%; ESAE, 375%; ESWAE, 693%), 3H-DPDPE (MTLE, 242%; ESAE, 80%; ESWAE, 346%) and 3H-nociceptin (MTLE, 424%; ESAE, 217%; ESWAE, 451%) binding was detected in the PHC of all epileptic groups. However, tissue obtained from ESAE group demonstrated lower opioid receptor binding (3H-DAMGO, 44.5%, p < 0.05; 3H-DPDPE, 47%, p < 0.05; 3H-nociceptin, 39.3%, p < 0.5) when compared with MTLE group. The present results indicate that a high effectiveness to the antiepileptic effects induced by HFS is associated with reduced opioid peptide binding. 相似文献
4.
5.
6.
Pyomyositis: characteristics at CT and MR imaging 总被引:9,自引:0,他引:9
7.
AJ Larner MRCP 《International journal of clinical practice》1994,48(5):272-274
SUMMARY A case is reported of pseudohyperphosphataemia in association with a monoclonal gammopathy of undetermined significance. 相似文献
8.
9.
Israel Lerman Liliana Lozano Antonio
R. Villa Sergio Hernndez-Jimnez Katie Weinger A. Enrique
Caballero Carlos Aguilar Salinas Maria Luisa Velasco Francisco Javier Gmez-Prez Juan
A. Rull 《Biomedicine & Pharmacotherapy》2004,58(10):566-570
To examine the relationship between demographic, clinical and psychosocial variables and diabetes self-care management in Mexican type 2 diabetic patients. Cross-sectional study of 176 consecutive patients with type 2 diabetes aged 30-75 years, attending a tertiary health-care center in Mexico City. A brief medical history and previously validated questionnaires were completed. The study group consisted of 64 males/112 females, aged 55 +/- 11 years, mean diabetes duration of 12 +/- 8 years and HbA1c of 9.0 +/- 2.0%, 78.4% reported following the correct dose of diabetes pills or insulin, 58% ate the recommended food portions, and 44.3% did exercise three or more times per week. A good adherence to these three recommendations was observed in only 26.1% of the patients. These patients considered as a group were characterized by a greater knowledge about the disease (P < 0.00001), regular home blood glucose monitoring (P < 0.01), an inner perception of better diabetes control (P = 0.007), good health (P = 0.004) and better communication with their physician (P < 0.02). A poor adherence to two or the three main diabetes care recommendations was associated with a depressive state (OR 2.38, 95% CI 1.1-4.9, P < 0.01) and a history of excessive alcohol intake (OR 4.03, 95% CI 1.1-21.0, P = 0.03). Poor adherence to standard diabetes care recommendations is frequently observed in patients with type 2 diabetes attending a specialized health care center in Mexico City. Depression must be identified and treated effectively. 相似文献
10.
D De AJ Kanwar S Handa 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):853-859
BACKGROUND: Diagnosis of atopic dermatitis (AD) depends on clinical features because no definitive diagnostic test exists. Criteria proposed by Hanifin and Rajka (Acta Derm Venereol (Stockh) 1980; Suppl 92: 44-47) were acceptable for hospital-based studies but were found not to be suitable for field studies. A UK working party formulated clinical diagnostic criteria that could be used in both hospital and epidemiological settings. Validation studies of the criteria showed widely variable results, probably due to different clinical settings and ethnicity. AIM AND OBJECTIVE: This study was undertaken to validate Hanifin and Rajka's criteria and to assess the comparative efficacy of their criteria and the UK working party's diagnostic criteria in the diagnosis of AD in a hospital setting in North India. SUBJECTS AND METHODS: This study serially included 101 patients with AD and 48 controls of paediatric age group. The study period was from July 2003 to December 2004. RESULTS: Hanifin and Rajka's criteria (sensitivity 96%, specificity 93.75%, positive predictive value 97% (PPV) and negative predictive value (NPV) 91.84%) had a statistical advantage over the UK working party's diagnostic criteria (sensitivity 86%, specificity 95.83%, PPV 97.75% and NPV 76.67%), with a P-value < 0.005. 相似文献