全文获取类型
收费全文 | 1249篇 |
免费 | 70篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 40篇 |
妇产科学 | 23篇 |
基础医学 | 132篇 |
口腔科学 | 18篇 |
临床医学 | 94篇 |
内科学 | 295篇 |
皮肤病学 | 20篇 |
神经病学 | 61篇 |
特种医学 | 179篇 |
外科学 | 129篇 |
综合类 | 39篇 |
预防医学 | 50篇 |
眼科学 | 20篇 |
药学 | 112篇 |
中国医学 | 17篇 |
肿瘤学 | 97篇 |
出版年
2023年 | 10篇 |
2022年 | 11篇 |
2021年 | 25篇 |
2020年 | 13篇 |
2019年 | 23篇 |
2018年 | 31篇 |
2017年 | 22篇 |
2016年 | 36篇 |
2015年 | 67篇 |
2014年 | 44篇 |
2013年 | 59篇 |
2012年 | 62篇 |
2011年 | 72篇 |
2010年 | 56篇 |
2009年 | 62篇 |
2008年 | 60篇 |
2007年 | 55篇 |
2006年 | 43篇 |
2005年 | 53篇 |
2004年 | 32篇 |
2003年 | 24篇 |
2002年 | 40篇 |
2001年 | 30篇 |
2000年 | 17篇 |
1999年 | 21篇 |
1998年 | 25篇 |
1997年 | 46篇 |
1996年 | 37篇 |
1995年 | 27篇 |
1994年 | 22篇 |
1993年 | 20篇 |
1992年 | 3篇 |
1991年 | 8篇 |
1990年 | 14篇 |
1989年 | 25篇 |
1988年 | 20篇 |
1987年 | 15篇 |
1986年 | 16篇 |
1985年 | 9篇 |
1984年 | 9篇 |
1983年 | 7篇 |
1982年 | 10篇 |
1981年 | 7篇 |
1980年 | 8篇 |
1978年 | 3篇 |
1977年 | 4篇 |
1976年 | 8篇 |
1973年 | 4篇 |
1968年 | 4篇 |
1961年 | 2篇 |
排序方式: 共有1333条查询结果,搜索用时 171 毫秒
1.
2.
3.
4.
Hausegger KA; Cragg AH; Lammer J; Lafer M; Fluckiger F; Klein GE; Sternthal MH; Pilger E 《Radiology》1994,190(1):199
5.
P Hercz P Siklos L Ungár R G Farquharson K Mohári L Kocsár 《European journal of obstetrics, gynecology, and reproductive biology》1987,24(3):189-193
The authors examined the possible role of HPL in the onset of labour. The HPL level of the maternal vein, the umbilical cord vein and artery was compared in vaginal mature (n = 16) and premature (n = 52) deliveries. The HPL concentration was also examined in mature (n = 18) and premature (n = 18) deliveries performed by caesarean section prior to the onset of labour. The results showed that: the serum HPL level in the maternal vein, the umbilical cord vein and artery was lower during the 33rd-36th and the 40th weeks in cases of vaginal delivery compared to elective caesarean section; The artery/vein ratio decreases during labour (A/V X 100 value), indicating that HPL metabolism in the fetus decreases during regular labour pains; The onset of premature labour and delivery was associated with lower HPL levels compared to normal pregnancy. The authors assume that the lower HPL level found in cases of vaginal delivery may be due to reduced placental perfusion, but they do not exclude the possible association of lower HPL concentrations in cases of premature delivery. 相似文献
6.
7.
8.
9.
10.
Detection of YMDD motif mutants by oligonucleotide chips in lamivudine-untreated patients with chronic hepatitis B virus infection 总被引:9,自引:0,他引:9
Heo J Cho M Kim HH Shin YM Jang HJ Park HK Kim CM Kim GH Kang DH Song GA Yang US 《Journal of Korean medical science》2004,19(4):541-546
Lamivudine, a nucleoside analogue, has been used widely as an effective antiviral agent for the treatment of patients with chronic hepatitis B virus (HBV) infection. However, the YMDD motif mutation of HBV polymerase resistant to lamivudine occurs very frequently after long term therapy. We developed an oligonucleotide chip for the detection of YMDD motif mutants resistant to lamivudine and investigated the prevalence of the mutants in patients with chronic HBV infection who had not been treated by lamivudine before. Forty patients who had not been treated with lamivudine were included in this study. Serum samples were tested by the oligonucleotide chips designed for detection of wild-type YMDD motif, M552V and M552I. Samples were confirmed by restriction fragment length polymorphism (RFLP) and direct sequencing. M552I mutants were detected by the oligonucleotide chips in 7.5% (3/40) of chronic HBV infected patients (2 chronic hepatitis and 1 cirrhosis). The results were in accordance with those of RFLP. YMDD motif mutants occur as natural genome variabilities in patients with chronic HBV infection who had not been treated with lamivudine before. Oligonucleotide chip technology is a reliable and useful diagnostic tool for the detection of mutants resistant to antiviral therapy in chronic HBV infection. 相似文献