全文获取类型
收费全文 | 33篇 |
免费 | 1篇 |
专业分类
妇产科学 | 2篇 |
基础医学 | 4篇 |
口腔科学 | 1篇 |
临床医学 | 2篇 |
内科学 | 13篇 |
皮肤病学 | 2篇 |
外科学 | 1篇 |
预防医学 | 3篇 |
眼科学 | 2篇 |
药学 | 1篇 |
肿瘤学 | 3篇 |
出版年
2012年 | 1篇 |
2011年 | 1篇 |
2008年 | 2篇 |
2005年 | 3篇 |
2004年 | 5篇 |
2003年 | 5篇 |
2002年 | 2篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1999年 | 1篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1992年 | 1篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1967年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有34条查询结果,搜索用时 15 毫秒
1.
Yamazaki H Nakatogawa N Ota Y Karakida K Otsuru M Kaneko A Shirasugi Y Kajiwara H 《Oral surgery, oral medicine, oral pathology and oral radiology》2012,113(6):e35-e39
Patients with head and neck squamous cell carcinoma are at an increased risk of developing second malignancies. Most commonly, these second primary malignancies are squamous cell carcinoma of the head and neck region, but also noted are esophageal cancer or lung cancer. Hematologic malignancies are uncommon second malignancies. Diagnosis can be challenging, particularly when a patient suffers metastases of squamous cell carcinoma to the cervical lymph nodes in addition to synchronous or metachronous malignant lymphoma that originates in the cervical lymph nodes. This article describes a case of primary follicular lymphoma in the cervical region that was discovered during a postoperative follow-up after partial glossectomy and neck dissection for tongue cancer. 相似文献
2.
Hirotaka Kurabayashi Akihiro Kaneko Ryo Sekiya Kazunari Karakida Masashi Sasaki Noriko Nakatogawa Takayuki Aoki Yoshihide Ota Haruo Sakamoto 《Journal of infection and chemotherapy》2011,17(1):40-44
After incubation of saliva from 58 semi-bedridden elderly persons, the cultures were identified based on the 16S rRNA gene
base sequence to compare the identification by the conventional culture method. As a result, the 16S rRNA gene base sequence
of 198 strains identified by the culture method showed 98.5% or more homology in some of the Human Oral Microbiome database,
and the identification of bacterial species and genus was possible. When an organism identified by the 16S rRNA gene sequencing
method was compared with that by the culture method, the concordance rates were 54.5% at the genus level and 35.9% at the
species level. Streptococcus mitis strains most frequently isolated from saliva that were identified by the culture method were identified as the same species
by the 16S rRNA gene sequencing method (32/35), and all the 11 Streptococcus salivarius strains identified by the culture method were identified as the same species by the 16S rRNA gene sequencing method. All
the strains identified as Streptococcus anginosus group by the culture method and 8 of the 9 strains identified as Prevotella species by the culture method were identified as the same group and genus by the 16S rRNA gene sequencing method. When an
oral microbial flora test with saliva samples from elderly persons is performed, the 16S rRNA gene sequence identification
enables us to identify major indigenous bacteria and pathogenic bacteria and is considered useful as a means of supplementing
the conventional culture method. 相似文献
3.
There are conflicting reports regarding the effect of dietary cholesterol-oxidation products (oxysterols) on the development of atherosclerosis in experimental animals. To address this issue, apolipoprotein (Apo) E-deficient mice were fed a purified diet (AIN-93) or the same purified diet containing 0.2 g cholesterol or 0.2 g oxysterols/kg. The dietary oxysterols had no significant effect on the serum lipid levels. Although all of the diet-derived oxysterols (cholest-5-en-3beta,7alpha-diol, cholest-5-en-3beta,7beta-diol, cholestan-5alpha,6alpha-epoxy-3beta-ol, cholestan-5beta,6beta-epoxy-3beta-ol, cholestan-3beta, 5alpha, 6beta-triol, cholest-5-en-3beta-ol-7-one and cholest-5-en-3beta, 25-diol) accumulated in the serum and liver, only cholest-5-en-3beta-ol-7-one and cholestan-3beta, 5alpha, 6beta-triol accumulated significantly (P<0.05) in the aorta. The oxysterol diet did not result in elevation of the aortic cholesterol level or the lesion volume in the aortic valve. These present results indicate that exogenous oxysterols do not promote the development of atherosclerosis in ApoE-deficient mice. 相似文献
4.
Tea catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by delaying lymphatic transport of dietary fat in rats 总被引:6,自引:0,他引:6
Ikeda I Tsuda K Suzuki Y Kobayashi M Unno T Tomoyori H Goto H Kawata Y Imaizumi K Nozawa A Kakuda T 《The Journal of nutrition》2005,135(2):155-159
Tea catechins, (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin gallate (ECG), and (-)-epigallocatechin gallate (EGCG), have been shown to be epimerized to (-)-catechin (C), (-)-gallocatechin (GC), (-)-catechin gallate (CG), and (-)-gallocatechin gallate (GCG), respectively, during heat treatment. In this study, we examined the effect of tea catechins rich in ECG and EGCG and heat-treated tea catechins rich in CG and GCG on postprandial hypertriacylglycerolemia in rats. Both tea catechins and heat-treated tea catechins suppressed postprandial hypertriacylglycerolemia. Lymphatic recovery of (14)C-trioleoylglycerol in rats cannulated in the thoracic duct was delayed by the administration of tea catechins and heat-treated tea catechins. Tea catechins and heat-treated tea catechins had the same effect on all variables tested. These catechin preparations dose-dependently inhibited the activity of pancreatic lipase in vitro. When purified catechins were used, only those with a galloyl moiety inhibited the activity of pancreatic lipase. These results suggest that catechins with a galloyl moiety suppress postprandial hypertriacylglycerolemia by slowing down triacylglycerol absorption through the inhibition of pancreatic lipase. Because postprandial hypertriacylglycerolemia is a risk factor for coronary heart disease, our results suggest that catechins with a galloyl moiety may prevent this disease. 相似文献
5.
Tomoyori H Kawata Y Higuchi T Ichi I Sato H Sato M Ikeda I Imaizumi K 《The Journal of nutrition》2004,134(7):1690-1696
Phytosterol oxidation products (oxyphytosterols) are formed during the processing and storage of foods. However, it is unknown whether oxyphytosterols affect human health. To address these issues, we prepared beta-sitosterol and campesterol oxides, evaluated their lymphatic absorption in rats, and examined the effect of an oxyphytosterol diet on atherosclerosis in apolipoprotein (apo) E-deficient mice. The lymphatic absorption of cholesterol and 6 oxyphytosterols (7alpha-hydroxy, 7beta-hydroxy, beta-epoxy, alpha-epoxy, dihydroxy, and 7-keto) of beta-sitosterol or campesterol was assessed in thoracic duct-cannulated rats fed an AIN-93G-based diet containing 2.5 g of cholesterol, oxyphytosterols, or intact phytosterols per kg. Lymphatic recoveries (on a mass basis) of oxycampesterols (15.9 +/- 2.8%, n = 10) and oxysitosterols (9.12 +/- 1.77%, n = 10) were higher than for campesterol (5.47 +/- 1.02%, n = 12, P < 0.05) and beta-sitosterol (2.16 +/- 0.37%, n = 12, P < 0.05), but lower than for cholesterol (37.3 +/- 8.3%, n = 6, P < 0.05). Apo E-deficient mice were fed an AIN-93G-based diet containing 0.2 g oxyphytosterols or intact phytosterols per kg for 9 wk. Diet-derived oxyphytosterols accumulated in the serum, liver, and aorta. Furthermore, the oxyphytosterol diet increased oxycholesterol in the serum compared to the phytosterol diet. However, there was no significant difference between the 2 groups in the serum and aortic cholesterol concentration, the lesion area in the aortic root, or 8-iso-prostaglandin F2alpha concentration in the urine. These results indicate that exogenous oxyphytosterols are well-absorbed and accumulate in the body, but do not promote the development of atherosclerosis in apo E-deficient mice. 相似文献
6.
N. Watada Y. Ikeda K. Kanzaki S. Fujiwara H. Tomoyori 《Digestive diseases and sciences》1999,44(1):217-228
Abstract List
Abstracts of Presentations from the Meeting on Infectious Pathogens in Gastrointestinal and Hepatic Disorders: Molecular Biology, Pathogenesis, and Therapeutic Implications Vall de Nuria, Spain September 15-19, 1998 相似文献7.
8.
9.
An 11-year-old Japanese female having acanthosis nigricans associated with Crouzon syndrome is reported. Crouzon syndrome is a craniostenotic craniofacial malformation associated with premature closure of selective calvarial sutures, exophthalmos, maxillary hypoplasia, and a beak-shaped nose. It is an autosomal dominant inherited disorder. Crouzon syndrome is one of the syndromes which may be associated with acanthosis nigricans. The association of acanthosis nigricans with Crouzon syndrome is assumed to be a rare abnormality, although the true frequency is uncertain. We have reviewed the reported cases of acanthosis nigricans associated with Crouzon syndrome and characteristics were discussed. 相似文献
10.
Nakatogawa T Hibi K Furukawa E Sugano T Kosuge M Takamura T Toda N Tsukahara K Okuda J Kimura K Umemura S 《The American journal of cardiology》2004,94(6):769-771
Fifty stented lesions in 50 patients with acute myocardial infarction were studied by intravascular ultrasound (IVUS) before and just after stent implantation and at follow-up. Volumetric IVUS analyses revealed that greater peristent positive remodeling after stent implantation was associated with less neointimal proliferation and greater luminal gain at follow-up. 相似文献