全文获取类型
收费全文 | 4499篇 |
免费 | 302篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 51篇 |
妇产科学 | 33篇 |
基础医学 | 618篇 |
口腔科学 | 130篇 |
临床医学 | 260篇 |
内科学 | 1506篇 |
皮肤病学 | 32篇 |
神经病学 | 244篇 |
特种医学 | 111篇 |
外科学 | 769篇 |
综合类 | 10篇 |
一般理论 | 1篇 |
预防医学 | 133篇 |
眼科学 | 51篇 |
药学 | 362篇 |
中国医学 | 13篇 |
肿瘤学 | 492篇 |
出版年
2023年 | 43篇 |
2022年 | 84篇 |
2021年 | 128篇 |
2020年 | 94篇 |
2019年 | 105篇 |
2018年 | 117篇 |
2017年 | 113篇 |
2016年 | 123篇 |
2015年 | 120篇 |
2014年 | 130篇 |
2013年 | 151篇 |
2012年 | 272篇 |
2011年 | 294篇 |
2010年 | 155篇 |
2009年 | 153篇 |
2008年 | 235篇 |
2007年 | 244篇 |
2006年 | 243篇 |
2005年 | 232篇 |
2004年 | 206篇 |
2003年 | 190篇 |
2002年 | 221篇 |
2001年 | 108篇 |
2000年 | 124篇 |
1999年 | 106篇 |
1998年 | 55篇 |
1997年 | 33篇 |
1996年 | 27篇 |
1995年 | 27篇 |
1994年 | 17篇 |
1993年 | 18篇 |
1992年 | 70篇 |
1991年 | 69篇 |
1990年 | 72篇 |
1989年 | 40篇 |
1988年 | 40篇 |
1987年 | 53篇 |
1986年 | 32篇 |
1985年 | 42篇 |
1984年 | 35篇 |
1983年 | 17篇 |
1981年 | 11篇 |
1979年 | 25篇 |
1977年 | 13篇 |
1976年 | 13篇 |
1975年 | 21篇 |
1974年 | 11篇 |
1973年 | 10篇 |
1971年 | 11篇 |
1969年 | 13篇 |
排序方式: 共有4826条查询结果,搜索用时 15 毫秒
1.
Masaru Sasaki Tsuyoshi Takahashi Soichiro Funaki Koji Tanaka Yasuhiro Miyazaki Naoko Ose Tomoki Makino Yukinori Kurokawa Makoto Yamasaki Kiyokazu Nakajima Yasushi Shintani Masaki Mori Yuichiro Doki 《Asian journal of endoscopic surgery》2021,14(1):116-119
We report a case of a diaphragmatic hernia after a heart transplant operation. A 43-year-old woman, who underwent orthotropic heart transplantation for hypertrophic cadiomyopathy two year earlier, presented with vomiting and epigastric pain. A computed tomography scan showed that the stomach and transverse colon were dislocated in the left thoracic cavity. We diagnosed left diaphragmatic hernia incarceration and performed laparoscopic repair of the diaphragmatic hernia. A 12 × 8 cm diaphragmatic defect was found intraoperatively on the ventrolateral aspect of the left diaphragm, and the stomach with volvulus had herniated into the thorax through the defect. The hernia was considered to be iatrogenic. The diaphragmatic defect was large, and the diaphragm was thinning. We closed the defect by mesh repair. Laparoscopic mesh repair of the diaphragmatic hernia could be performed safely and with minimal invasiveness. 相似文献
2.
3.
Yutaka Senga Seiichiro Ozono Hayakazu Nakazawa Satoshi Nagamori Ken Marumo Shigeo Horie Tetsuro Onishi Noriomi Miyao Masahiro Nakao Tatsuo Igarashi Tomoyasu Tsushima Michihiko Hasegawa Masaru Murai the Japanese Society of Renal Cancer 《International journal of urology》2007,14(4):284-288
OBJECTIVE: A joint study was undertaken by the Japanese Society of Renal Cancer to investigate the present status of partial nephrectomy in Japan and to speculate about what may be the indications for partial nephrectomy in patients with renal cell carcinoma. METHODS: Data were tabulated for 469 patients from participating medical institutions and various clinical factors were investigated with regard to disease progression (local recurrence and distant metastasis). RESULTS: Disease progression was observed in 21 patients (4.5%). No significant relation to disease progression was observed for sex, laterality, tumor histology, grade and tumor size. Although patients with solitary tumors displayed excellent prognosis irrespective of tumor diameter, patients with multiple tumors displayed a high likelihood of disease progression. Patients older than 77 years old and patients with imperative indication were found to have a poorer prognosis. CONCLUSION: In patients with solitary tumors, partial nephrectomy can be actively performed, even if the patient displays elective indications and the tumor is >4 cm in diameter. In patients displaying multiple tumors with imperative indications, the decision whether to perform partial nephrectomy should be made by the patients and their physicians after considering the impact on curability and the quality of life. 相似文献
4.
Yuji Takeda Naoki Minato Yuji Katayama Tomoki Shimokawa 《General thoracic and cardiovascular surgery》2005,53(1):42-45
Two successful cases of the surgical treatment for coronary artery aneurysm (non-Kawasaki disease) were reported. The first
case had a saccular aneurysm on the left circumflex coronary artery (LCx) #14. Resection of the LCx aneurysm was performed
subsequent to single vessel coronary artery bypass grafting (CABG) to the distal portion of LCx#14 under the cardioplegic
cardiac arrest. The second case had aneurysms on both the left anterior descending artery (LAD) #7 (fusiform) and the LCx#11
(saccular). After double vessel CABG to LAD#7 and LCx#11, ligation or resection of two aneurysms was performed successfully.
Postoperative courses have been uneventful with good angiographic results achieved. Since these surgical procedures demonstrated
safety, the patients are expected to achieve a good long-term prognosis. 相似文献
5.
6.
Masayuki Mano Akira Sugawara Yasuo Nara Kazuwa Nakao Ryoichi Horie Jiro Endo Hiroo Imura Yukio Yamori 《Clinical and experimental pharmacology & physiology》1992,19(12):795-801
1. Effects of potassium (K) supplementation (100 mEq/day) on urinary sodium (Na) excretion and on the secretion of atrial natriuretic polypeptide (ANP) during salt loading (350 mEq/day) were studied in 12 healthy salt-resistant normotensives under strictly controlled metabolic ward conditions. 2. Urinary volume and Na excretion on the first day of the high salt period (HSP) were significantly greater in the K-supplemented group (KG) than in the control group (CG). 3. There was a significant gain in bodyweight after salt loading in both groups, with a significantly greater gain in CG on the second day of HSP. Haematocrit decreased significantly during salt loading in both groups, the degree of which was significantly greater in CG. 4. Plasma norepinephrine decreased significantly during salt loading in both groups, the degree of which was significantly less in KG than in CG. A significant increase in plasma ANP was observed in CG on and after the second day of HSP, while a significant increase in plasma ANP was observed on the fifth day of HSP in KG. 5. These findings indicate that K supplementation accelerates diuresis and natriuresis, resulting in moderate suppression of volume expansion induced by salt loading and that this accelerated diuresis and natriuresis is not a result of the action of ANP. 相似文献
7.
8.
The effects of 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS), an inhibitor of the Cl(-)-HCO3- exchanger, and amiloride, an inhibitor of the Na(+)-H+ exchanger, on gastric acid secretion under basal conditions and after stimulation with bethanechol or dibutyryl cyclic AMP were studied in rat gastric mucosa sheet preparation. DIDS inhibited bethanechol-induced acid secretion in a dose-dependent manner, but amiloride had no effect. The stimulation of acid secretion by dibutyryl cyclic AMP plus 3-isobutyl-1-methylxanthine was also inhibited by DIDs, but not by amiloride. DIDS did not reduce basal acid secretion, and neither did amiloride. These results suggest that the Cl(-)-HCO3-exchanger in the basolateral membrane of the parietal cell plays an important role in stimulated gastric acid secretion and that the Na(+)-H+ exchanger is less important. In addition, these data show that DIDS inhibits stimulated gastric acid secretion irrespective of the secretagogue, but not basal gastric acid secretion. 相似文献
9.
10.