全文获取类型
收费全文 | 668篇 |
免费 | 64篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 33篇 |
妇产科学 | 31篇 |
基础医学 | 201篇 |
口腔科学 | 15篇 |
临床医学 | 53篇 |
内科学 | 119篇 |
皮肤病学 | 18篇 |
神经病学 | 29篇 |
特种医学 | 8篇 |
外科学 | 68篇 |
综合类 | 37篇 |
预防医学 | 45篇 |
眼科学 | 10篇 |
药学 | 36篇 |
中国医学 | 1篇 |
肿瘤学 | 39篇 |
出版年
2022年 | 5篇 |
2021年 | 21篇 |
2020年 | 12篇 |
2019年 | 11篇 |
2018年 | 12篇 |
2017年 | 12篇 |
2016年 | 11篇 |
2015年 | 14篇 |
2014年 | 25篇 |
2013年 | 32篇 |
2012年 | 33篇 |
2011年 | 41篇 |
2010年 | 18篇 |
2009年 | 26篇 |
2008年 | 22篇 |
2007年 | 55篇 |
2006年 | 16篇 |
2005年 | 27篇 |
2004年 | 26篇 |
2003年 | 25篇 |
2002年 | 22篇 |
2001年 | 10篇 |
2000年 | 14篇 |
1999年 | 8篇 |
1998年 | 6篇 |
1997年 | 8篇 |
1996年 | 13篇 |
1995年 | 11篇 |
1994年 | 6篇 |
1993年 | 10篇 |
1992年 | 17篇 |
1991年 | 13篇 |
1990年 | 20篇 |
1989年 | 17篇 |
1988年 | 17篇 |
1987年 | 16篇 |
1986年 | 10篇 |
1985年 | 11篇 |
1984年 | 6篇 |
1982年 | 7篇 |
1981年 | 4篇 |
1980年 | 16篇 |
1979年 | 13篇 |
1978年 | 13篇 |
1977年 | 4篇 |
1976年 | 4篇 |
1975年 | 7篇 |
1973年 | 2篇 |
1969年 | 2篇 |
1966年 | 2篇 |
排序方式: 共有760条查询结果,搜索用时 15 毫秒
1.
2.
肩、肘关节外科新进展 总被引:1,自引:0,他引:1
肩关节(Shoulder)
旋转袖(Rotator Cuff)
基础研究(Basic Science)
Zuckerman讨论了软骨诱导形态发生蛋白-2(cartilagederived morphogenetic protein-2,CDMP-2)的早期工作。在鼠肌腱修复中,4周时CDMP-2治疗组的修复强度高于未治疗组。Dines讨论了关于血小板衍生生长因子(platelet—derived growth factor,PDGF)和胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)最初的研究观察。 相似文献
3.
Serum immunoglobulins including IgG subclasses were measured in 73 unselected children with asthma. The results showed that 22 (30%) had partial IgA and/or IgG4 subclass deficiency. Clinical assessment showed that 21 children were infection-prone, and 52 were not. Further analysis showed that infection-prone children were significantly different from non-infection-prone children with regard to familial history of allergy (29% vs 60%, p = 0.015), elevated IgE (62% vs 33%, p = 0.021), IgA deficiency (38% vs 15%, p = 0.38) and IgG subclass deficiency (24% vs 4%, p = 0.018). These results suggest that there may be subgroups of children with asthma who are also immunodeficient. 相似文献
4.
7-甲氧基-4′-羟基-3′-二乙胺甲基异黄酮(MHDF)对大鼠血流动力学和主动脉的作用 总被引:2,自引:0,他引:2
本实验观察了MHDF对整体大鼠血流动力学和离体大鼠胸主动脉的作用。结果表明iv MHDF(3~12.8 mg/kg)能降低大鼠左心室±dp/dtmax,Vmax,Vpm和LVSP,延长T-dp/dtmax,减慢心率。MHDF还能舒张大鼠胸主动脉,ED50为6.5×10-6mol/L;非竞争拮抗NA和CaCl2致主脉收缩,pD2′为3.11±0.21和3.73±0.07;抑制高K+致主动脉收缩,IC50为1.76×10-5mol/L。提示MHDF对血管的作用与α受体阻断剂不同,而可能与钙拮抗有关。 相似文献
5.
6.
The effects of the bisbenzylisoquinoline alkaloids tetrandrine and berbamine on the action of IL-1, TNF and PAF were investigated in the rat subcutaneous air pouch model of inflammation. Both compounds were equipotent in the suppression of leukocyte infiltration into air pouches induced by IL-1 and TNF, with ED50 values in the range 20–30 mg/kg/3 days. Both were also equiptent in suppression of PMN infiltration induced by PAF with ED50 values in the same range as that for IL-1 and TNF. However, tetrandrine was more potent than berbamine as a suppressant of PAF-induced MNC infiltration, but much less potent than berbamine in carageenen-induced PMN infiltration. These results suggest that these bisbenzylisoquinolines may have value in the therapy of chronic inflammatory diseases where IL-1, TNF and PAF have a role in pathogenesis. 相似文献
7.
8.
Four species of Naegleria were tested for their ability to migrate under agarose. Pathogenic N. fowleri strains exhibited rapid locomotion at 37 degrees C. Environmental isolates of N. fowleri moved faster than clinical isolates which had been kept in axenic culture for longer periods, and this result was confirmed by using the 84-2205-7 strain kept in axenic culture for 1 or 5 months. Nonpathogenic N. gruberi strains migrated actively at 28 degrees C but not at 37 degrees C; moreover, even at 28 degrees C, active amoebae constituted only a small proportion of the whole. The temperature-tolerant, nonpathogenic species N. lovaniensis moved more slowly than N. fowleri at 37 degrees C. In contrast, N. australiensis, which is temperature tolerant as well as pathogenic for mice, migrated at a rate comparable to that of N. fowleri. There appears to be a direct correlation between the locomotive ability of free-living amoebae and their pathogenic potential. 相似文献
9.
Effect of twenty-three chemotherapeutic agents on the adherence and growth of Giardia lamblia in vitro 总被引:3,自引:0,他引:3
A A Crouch W K Seow Y H Thong 《Transactions of the Royal Society of Tropical Medicine and Hygiene》1986,80(6):893-896
The sensitivity of Giardia lamblia to 23 chemotherapeutic agents was evaluated in vitro with a Growth Inhibition Assay and a recently developed Adherence Inhibition Assay. Of the four established anti-giardia drugs, tinidazole, metronidazole, and furazolidone were found to have strong inhibitory effects on both growth and adherence, while mepacrine had a strong effect on growth only. Three drugs (mefloquine, doxycycline and rifampin) not previously used in giardiasis were found to have significant activity in vitro and may deserve consideration for clinical evaluation of efficacy. Also, the concurrent use of these two in vitro methods provided significant insights into the modes of action of some of these drugs on G. lamblia. 相似文献
10.
Eva Maria Cutiongco‐de la Paz Brian Hon‐Yin Chung Sultana M. H. Faradz Meow‐Keong Thong Carmencita David‐Padilla Poh San Lai Shuan‐Pei Lin Yin‐Hsiu Chen Thanyachai Sura Mercy Laurino 《American journal of medical genetics. Part C, Seminars in medical genetics》2019,181(2):177-186
The status of training in clinical genetics and genetic counseling in Asia is at diverse stages of development and maturity. Most of the training programs are in academic training centers where exposure to patients in the clinics or in the hospital is a major component. This setting provides trainees with knowledge and skills to be competent geneticists and genetic counselors in a variety of patient care interactions. Majority of the training programs combine clinical and research training which provide trainees a broad and integrated approach in the diagnosis and management of patients while providing opportunities for research discoveries that can be translated to better patient care. The background on how the training programs in clinical genetics and genetic counseling in Asia evolved to their current status are described. Each of these countries can learn from each other through sharing of best practices and resources. 相似文献