全文获取类型
收费全文 | 30738篇 |
免费 | 1887篇 |
国内免费 | 354篇 |
专业分类
耳鼻咽喉 | 141篇 |
儿科学 | 1259篇 |
妇产科学 | 498篇 |
基础医学 | 2837篇 |
口腔科学 | 378篇 |
临床医学 | 3282篇 |
内科学 | 8162篇 |
皮肤病学 | 363篇 |
神经病学 | 2044篇 |
特种医学 | 589篇 |
外科学 | 2895篇 |
综合类 | 2909篇 |
一般理论 | 4篇 |
预防医学 | 2786篇 |
眼科学 | 855篇 |
药学 | 1600篇 |
中国医学 | 716篇 |
肿瘤学 | 1661篇 |
出版年
2024年 | 32篇 |
2023年 | 208篇 |
2022年 | 173篇 |
2021年 | 282篇 |
2020年 | 244篇 |
2019年 | 113篇 |
2018年 | 446篇 |
2017年 | 424篇 |
2016年 | 529篇 |
2015年 | 544篇 |
2014年 | 611篇 |
2013年 | 945篇 |
2012年 | 1777篇 |
2011年 | 2272篇 |
2010年 | 964篇 |
2009年 | 856篇 |
2008年 | 2013篇 |
2007年 | 1892篇 |
2006年 | 1674篇 |
2005年 | 1981篇 |
2004年 | 2750篇 |
2003年 | 2834篇 |
2002年 | 2204篇 |
2001年 | 1802篇 |
2000年 | 900篇 |
1999年 | 808篇 |
1998年 | 660篇 |
1997年 | 485篇 |
1996年 | 305篇 |
1995年 | 241篇 |
1994年 | 265篇 |
1993年 | 376篇 |
1992年 | 261篇 |
1991年 | 207篇 |
1990年 | 172篇 |
1989年 | 111篇 |
1988年 | 92篇 |
1987年 | 100篇 |
1986年 | 83篇 |
1985年 | 67篇 |
1984年 | 43篇 |
1983年 | 28篇 |
1982年 | 15篇 |
1981年 | 22篇 |
1980年 | 15篇 |
1979年 | 15篇 |
1978年 | 23篇 |
1977年 | 16篇 |
1976年 | 10篇 |
1974年 | 13篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
New Zealand Emergency Medicine Network: A collaboration for acute care research in New Zealand
下载免费PDF全文
![点击此处可从《Emergency medicine Australasia : EMA》网站下载免费的PDF全文](/ch/ext_images/free.gif)
The specialty of emergency medicine in Australasia is coming of age. As part of this maturation there is a need for high‐quality evidence to inform practice. This article describes the development of the New Zealand Emergency Medicine Network, a collaboration of committed emergency care researchers who share the vision that New Zealand/Aotearoa will have a world‐leading, patient‐centred emergency care research network, which will improve emergency care for all, so that people coming to any ED in the country will have access to the same world‐class emergency care. 相似文献
2.
3.
L. Misery E. Weisshaar E. Brenaut A.W.M. Evers F. Huet S. Ständer A. Reich E. Berardesca E. Serra-Baldrich J. Wallengren D. Linder J.W. Fluhr J.C. Szepietowski H. Maibach for the Special Interest Group on sensitive skin of the International Forum for the Study of Itch 《Journal of the European Academy of Dermatology and Venereology》2020,34(2):222-229
The special interest group on sensitive skin of the International Forum for the Study of Itch previously defined sensitive skin as a syndrome defined by the occurrence of unpleasant sensations (stinging, burning, pain, pruritus and tingling sensations) in response to stimuli that normally should not provoke such sensations. This additional paper focuses on the pathophysiology and the management of sensitive skin. Sensitive skin is not an immunological disorder but is related to alterations of the skin nervous system. Skin barrier abnormalities are frequently associated, but there is no cause and direct relationship. Further studies are needed to better understand the pathophysiology of sensitive skin – as well as the inducing factors. Avoidance of possible triggering factors and the use of well-tolerated cosmetics, especially those containing inhibitors of unpleasant sensations, might be suggested for patients with sensitive skin. The role of psychosocial factors, such as stress or negative expectations, might be relevant for subgroups of patients. To date, there is no clinical trial supporting the use of topical or systemic drugs in sensitive skin. The published data are not sufficient to reach a consensus on sensitive skin management. In general, patients with sensitive skin require a personalized approach, taking into account various biomedical, neural and psychosocial factors affecting sensitive skin. 相似文献
4.
Parallel enzyme‐linked immunosorbent assay screening for human immunodeficiency virus among blood donors in five Chinese blood centres: a retrospective analysis
下载免费PDF全文
![点击此处可从《Transfusion medicine (Oxford, England)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
5.
6.
Comparative safety study on severe anemia by simeprevir versus telaprevir‐based triple therapy for chronic hepatitis C
下载免费PDF全文
![点击此处可从《Journal of gastroenterology and hepatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Eiichi Ogawa Norihiro Furusyo Eiji Kajiwara Hideyuki Nomura Akira Kawano Kazuhiro Takahashi Kazufumi Dohmen Takeaki Satoh Koichi Azuma Makoto Nakamuta Toshimasa Koyanagi Kazuhiro Kotoh Shinji Shimoda Jun Hayashi The Kyushu University Liver Disease Study Group 《Journal of gastroenterology and hepatology》2015,30(8):1309-1316
7.
M. Masson Regnault J. Castañeda-Sanabria M.H.T. Diep Tran M. Beylot-Barry H. Bachelez N. Beneton O. Chosidow A. Dupuy P. Joly D. Jullien E. Mahé M.-A. Richard M. Viguier F. Tubach E. Sbidian C. Paul The PsoBioTeq Study Group 《Journal of the European Academy of Dermatology and Venereology》2020,34(2):293-300
8.
9.
10.
Prevention of Bone Loss by Clodronate in Early Postmenopausal Women with Vertebral Osteopenia: A Dose-Finding Study 总被引:1,自引:0,他引:1
M. J. V?lim?ki K. Laitinen K. Laitinen A. Patronen H. Puolijoki H. Puolijoki J. Sepp?nen L. Pylkk?nenand the Probone Study Group 《Osteoporosis international》2002,13(12):937-947
This double-masked, placebo-controlled study was undertaken to determine the efficacy and safety of oral clodronate in the
prevention of bone loss in early postmenopausal women with vertebral osteopenia. Altogether 610 women with a mean age of 53
years were recruited for the study. They were 1–5 years postmenopausal and their lumbar spine bone mineral density (BMD) was
at least 1 standard deviation below the mean of premenopausal women (T-score ≤−1). The subjects were randomized into five study groups to receive either placebo, clodronate 65 mg, 400 mg or 800
mg daily, or intermittent clodronate in 3 month cycles with 400 mg daily for 15 days followed with no treatment for 75 days
for 3 years. One hundred and eighty-seven of 509 women who completed the primary study continued in the extension study of
2 years in which previous placebo users were switched to clodronate 800 mg daily, while previous users of 400 mg or 800 mg
of clodronate used either placebo or 800 mg of clodronate daily. In the primary study clodronate was administered in the evening,
and in the extension 1 h before breakfast on an empty stomach. In the primary study mean changes in lumbar spine BMD were
−3.4% in the placebo group and +0.4% in 800 mg clodronate group [difference between groups at 3 years 3.8% (95% CI 2.7% to
4.9%, p<0.0001)], and in the trochanter area BMD −1.1% in the placebo group, and + 0.4% in the 800 mg clodronate group [difference
between groups at 3 years 1.5% (95% CI 0.05% to 2.9%)]. During the extension study mean changes in lumbar spine BMD were +1.5%
in the clodronate group and −0.2 % in the placebo group [difference between groups 1.7% (CI 0.4% to 3.0%, p = 0.010)] and in trochanter BMD were +2.5% in the clodronate group and no change in the placebo group [difference between
groups 2.1% (CI 0.3% to 3.9%, p = 0.007)]. No statistically significant differences between the placebo and 800 mg clodronate groups were found in the femoral
neck BMD. In the primary study the urinary excretion of type I collagen aminoterminal telopeptide (NTX) decreased by 44% (p<0.0001 compared with placebo) and that of deoxypyridinoline by 18% (p<0.0001) in the clodronate 800 mg group. In the extension study urinary NTX decreased by 51% (p<0.0001) in those who were switched to 800 mg of clodronate and increased by 67% (p<0.0001) in those who stopped using that dose. There was no difference in the frequency of gastrointestinal complaints between
clodronate- and placebo-treated patients in the primary study, but they were more common among women who received clodronate
in the extension phase. Clodronate in daily doses of 400–800 mg caused a slight elevation of aminotransferase levels, usually
within the reference range. In bone biopsies no defect in mineralization was found. In conclusion, clodronate in a daily dose
of 800 mg prevents early postmenopausal bone loss at the sites of the skeleton in which cancellous bone predominates. It effectively
reduces bone resorption and bone turnover rate. Antifracture efficacy of clodronate remains to be established by prospective,
placebo-controlled trials.
Received: 4 March 2002 / Accepted: 9 July 2002 相似文献