首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2103篇
  免费   159篇
  国内免费   21篇
耳鼻咽喉   15篇
儿科学   45篇
妇产科学   15篇
基础医学   306篇
口腔科学   52篇
临床医学   174篇
内科学   496篇
皮肤病学   27篇
神经病学   109篇
特种医学   107篇
外科学   285篇
综合类   218篇
一般理论   3篇
预防医学   94篇
眼科学   37篇
药学   89篇
中国医学   3篇
肿瘤学   208篇
  2023年   18篇
  2022年   32篇
  2021年   119篇
  2020年   54篇
  2019年   53篇
  2018年   68篇
  2017年   48篇
  2016年   55篇
  2015年   77篇
  2014年   86篇
  2013年   94篇
  2012年   132篇
  2011年   158篇
  2010年   80篇
  2009年   85篇
  2008年   96篇
  2007年   104篇
  2006年   92篇
  2005年   94篇
  2004年   84篇
  2003年   73篇
  2002年   64篇
  2001年   47篇
  2000年   66篇
  1999年   54篇
  1998年   40篇
  1997年   33篇
  1996年   28篇
  1995年   12篇
  1994年   14篇
  1993年   12篇
  1992年   16篇
  1991年   31篇
  1990年   17篇
  1989年   30篇
  1988年   13篇
  1987年   15篇
  1986年   17篇
  1985年   16篇
  1984年   9篇
  1983年   12篇
  1982年   6篇
  1981年   4篇
  1980年   4篇
  1979年   4篇
  1978年   4篇
  1977年   5篇
  1976年   3篇
  1973年   2篇
  1971年   1篇
排序方式: 共有2283条查询结果,搜索用时 15 毫秒
1.
2.
Background  Stress gated myocardial perfusion single photon emission computed tomography (gSPECT) is increasingly used before and after intercurrent therapeutic intervention and is the basis for ongoing evaluation in the Department of Veterans Affairs clinical outcomes utilizing revascularization and aggressive drug evaluation (COURAGE) trial. Methods and Results  The COURAGE trial is a North American multicenter randomized clinical trial that enrolled 2287 patients to aggressive medical therapy vs percutaneous coronary intervention plus aggressive medical therapy. Three COURAGE nuclear substudies have been designed. The goals of substudy 0 are to examine the diagnostic accuracy of the extent and severity of inducible ischemia at baseline in COURAGE patients compared with patient symptoms and quantitative coronary angiography and to explore the relationship between inducible ischemia and the benefit from revascularization when added to medical therapy. Substudy 1 will correlate the extent and severity of provocative ischemia with the frequency, quality, and instability of recurrent symptoms in postcatheterization patients. Substudy 2 (n _ 300) will examine the usefulness of sequential gSPECT monitoring 6 to 18 months after therapeutic intervention. Together, these nuclear substudies will evaluate the role of gSPECT to determine the effectiveness of aggressive risk-factor modifications, lifestyle interventions, and anti-ischemic medical therapies with or without revascularization in reducing patients’ ischemic burdens. Conclusions  The unfolding of evidence on the application of gSPECT in trials such as COURAGE defines a new era for nuclear cardiology. We hope the evidence that emerges from the COURAGE trial will further establish the role of nuclear imaging in the evidence-based management of patients with stable coronary disease. The COURAGE trial was supported by the Cooperative Studies Program of the Department of Veterans Affairs Office of Research and Development in collaboration with the Canadian Institutes of Health Research. Unrestricted research grants were obtained from Merck & Co; Pfizer Pharmaceuticals; Bristol-Myers Squibb Medical Imaging; Astellas Pharma; Kos Pharmaceuticals; Data Scope; Astra Zeneca Pharmaceuticals; Astra-Zeneca-Canada; Schering-Plough Coorporation, Ltd; Sanofi-Aventis, Inc; First Horizon; and GE Healthcare. All industrial funding for this trial was directed through the Department of Veterans Affairs. Additional funding for this substudy was provided by grants to the Department of Veterans Affairs and Canadian Institutes of Health Research from Astellas Pharma and Bristol-Myers-Squibb Medical Imaging.  相似文献   
3.
4.
5.
Needle core biopsy guided with mammography: a study of cost- effectiveness   总被引:2,自引:0,他引:2  
Lindfors  KK; Rosenquist  CJ 《Radiology》1994,190(1):217
  相似文献   
6.
7.
CG Teo 《Oral diseases》2002,8(S2):88-90
Oral hairy leukoplakia (OHL) and Kaposi's sarcoma (KS) are commonly encountered in the HIV-infected patient. A unique feature of OHL is non-cytolytic high level of replication of Epstein–Barr virus (EBV) in the glossal epithelium. The expression of viral-encoded anti-apoptotic proteins concomitant to replicative proteins probably underlies this phenomenon. The question of whether OHL arises from activation of EBV latent in the tongue, or from superinfection by endogenous EBV shed via non-glossal sites or by exogenous EBV remains unresolved. Human herpesvirus 8 (HHV8) is now seen as necessary but not sufficient cause of KS. Expression of HHV8-encoded oncogenic proteins in endothelial cells probably explains the aberrant proliferation of these cells in KS lesions. Studies into why KS is so commonly observed at the palate in HIV-infected patients may provide important clues to its pathogenesis.  相似文献   
8.
9.
A sciatic nerve lesion is uncommon. We report the utility of the endoscope in an 18-year-old female with multiple lesions of her sciatic nerve. Somatosensory evoked potentials and MRI were indicative of a sciatic nerve lesion. We describe a simple technique of endoscopic exploration of the sciatic nerve to assist intraoperative decision making.  相似文献   
10.
Despite empirical evidence that cardiac rehabilitation programs can play a significant role in enhancing recovery following a primary cardiac event and in enacting secondary prevention measures, attendance rates remain remarkably low. Referral and attendance at cardiac rehabilitation programs are not one and the same. Recognizing this, issues related to the referral of eligible patients to cardiac rehabilitation and factors that affect patients' decisions regarding attendance must be identified and addressed. This article presents an overview of the potential benefits of cardiac rehabilitation programs, describes salient issues related to referral and attendance, and identifies directions for future research.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号