全文获取类型
收费全文 | 529篇 |
免费 | 16篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 15篇 |
妇产科学 | 4篇 |
基础医学 | 116篇 |
口腔科学 | 7篇 |
临床医学 | 79篇 |
内科学 | 63篇 |
皮肤病学 | 3篇 |
神经病学 | 14篇 |
特种医学 | 24篇 |
外科学 | 28篇 |
综合类 | 29篇 |
预防医学 | 43篇 |
眼科学 | 24篇 |
药学 | 103篇 |
肿瘤学 | 27篇 |
出版年
2021年 | 6篇 |
2018年 | 6篇 |
2017年 | 6篇 |
2016年 | 4篇 |
2015年 | 15篇 |
2014年 | 14篇 |
2013年 | 14篇 |
2012年 | 9篇 |
2011年 | 14篇 |
2010年 | 17篇 |
2009年 | 15篇 |
2008年 | 11篇 |
2007年 | 40篇 |
2006年 | 19篇 |
2005年 | 21篇 |
2004年 | 12篇 |
2003年 | 14篇 |
2002年 | 21篇 |
2001年 | 21篇 |
2000年 | 18篇 |
1999年 | 12篇 |
1998年 | 24篇 |
1997年 | 22篇 |
1996年 | 9篇 |
1995年 | 12篇 |
1994年 | 11篇 |
1993年 | 10篇 |
1992年 | 13篇 |
1991年 | 26篇 |
1990年 | 17篇 |
1989年 | 19篇 |
1988年 | 12篇 |
1987年 | 10篇 |
1986年 | 5篇 |
1985年 | 7篇 |
1983年 | 5篇 |
1981年 | 4篇 |
1978年 | 3篇 |
1977年 | 3篇 |
1976年 | 9篇 |
1975年 | 8篇 |
1974年 | 5篇 |
1973年 | 4篇 |
1972年 | 7篇 |
1971年 | 5篇 |
1970年 | 3篇 |
1969年 | 4篇 |
1968年 | 3篇 |
1967年 | 4篇 |
1966年 | 3篇 |
排序方式: 共有595条查询结果,搜索用时 15 毫秒
1.
2.
YS Nagar S Singh V Sawlani L Pal K Dimri P Lal 《Journal of Medical Imaging and Radiation Oncology》2005,49(2):160-162
A rare case of an advanced primary broad ligament carcinoma is discussed, with a review of the literature regarding its incidence, presentation and management. This patient showed a complete response to adjuvant cisplatin-based chemotherapy following panhysterectomy and is presently without any evidence of disease, 15 months after completion of her treatment. 相似文献
3.
The activity of lyophilized Soviet reference plasma Factor VIII was measured by a single-stage Papayan and Khrolova's method. This factor is referent in respect of the prothrombin complex factors, stored for 18-43.5 months. Factor VIII activity was found to be within 55-135 percent. Differences in the values of antihemophilic globulin activities obtained in parallel studies in different days may be explained by the fact that the native control was not standard. The results are promising as regards the possibility of using lyophilized donor reference plasma as a reference reagent for estimation of Factor VIII activity. 相似文献
4.
5.
LEE JS IM HH JUNG Y JUNG IS JANG JY CHUN YK CHO YD KIM JO CHO JY KIM YS SHIM CS & KIM BS 《Neurogastroenterology and motility》2006,18(6):493-494
Background: Recent development of extracorporeal magnetic stimulation (ECMS) which uses current‐changing magnetic fields allows the induction of electrical stimulation in the desired deep tissue. Recent study showed the sacral nerve stimulation reduces corticoanal excitability that may play a functional role in anal continence mechanisms. Preliminary study shows that ECMS of sacral nerve can modify pelvic floor function and expel rectal balloon in patients with pelvic floor dyssynergia (PFD). Aims: To evaluate the effect of ECMS compared with biofeedback therapy (BF) in patients with PFD. Methods and Materials: Thirty‐eight patients who fulfilled Rome II criteria for PFD by colon transit time and anorectal function tests, were randomly treated with 8 sessions of ECMS (2/weeks; n = 19) at prone position or BF (2/weeks; n = 19) at sitting position. Stimulation parameters were set at 50–80% of maximum intensity, 10 and 50 Hz frequency, 3 s burst length with 3 and 6 s off using arm‐typed stimulator (BioCom‐1000, Mcube Co., Korea). Symptom scores for constipation with/without anorectal function test were repeatedly measured after each treatment. Response was defined as 50% or more decreased symptom score after treatment (partial response: 30–50%, poor: <30%). Results: Fifteen patients (age 49.1 ± 13.4 years, mean ± SD; 4 men) completed 8 session of BF and 14 patients (54.5 ± 17.6 years, 3 men) completed 8 session of ECMS. Four patients of BF group discontinued treatment due to unsatisfactory therapeutic effect (n = 1) and withdrew consent (n = 3) and 5 patients of ECMS group discontinued treatment because of same reasons (n = 1, 4). Total symptom scores were significantly decreased after treatment of 8 session in both treatment groups (13.4 ± 6.6 vs. 4.3 ± 4.0 for BF, p = 0.009; 14.9 ± 5.6 vs. 3.4 ± 4.0 for ECMS, p < 0.001). Bowel movements per week were also significantly increased after treatment in both groups (median 2 vs. 7 for BF, p = 0.035; median 2 vs. 7 for ECMS, p = 0.008). Thirteen out of 15 patients showed response in BF group and 12 out of 14 showed good response in ECMS group. No adverse effects in both groups. Conclusions: ECMS is as effective as BF for the treatment of PFD. Long‐term effect of ECMS for the patients with pelvic floor dyssynergia need to be evaluated in the near future. 相似文献
6.
In urethane-anaesthetized rats the effects of alpha-adrenoceptor antagonists and desensitization of P2-purinoceptors with alpha,beta-methylene ATP on the pressor reflex responses were investigated. Pressor responses were elicited by electrical stimulation of the central end of the sciatic nerve, by asphyxia and by occlusion of the common carotid artery. Responses to sciatic nerve stimulation and to asphyxia, but not those to carotid artery occlusion were entirely suppressed by dihydroergotamine and phentolamine. Under the action of dihydroergotamine the sinocarotid reflex decreased by over 70% in 40% of the experiments. In 60% of experiments the response was only slightly reduced or even augmented, but it was entirely inhibited by subsequent desensitization with alpha,beta-methylene ATP. The magnitude of response to sciatic nerve stimulation was almost unaffected by alpha,beta-methylene ATP, while the response to carotid occlusion was decreased by 40-50%. The recovery of purinoceptor sensitivity to alpha,beta-methylene ATP was accompanied by restoration of the sinocarotid reflex. It is suggested that purinergic neurotransmission plays a considerable role in the pressor sinocarotid reflex, while in the pressor response to stimulation of somatic afferents its role is negligible. 相似文献
7.
8.
对10名男性受试者单剂量po240mgVer缓释片药代动力学及心电图变化进行研究。血药浓度—时间数据用零级吸收过程的一室模型拟合,其药代动力学参数:Tmax5.9±1.6h;Cmax118.9±37.2μg·L-1;T1 5.4±1.5h;k030.5±17.5μg·L-1·h-1;T1/210.8±4.9h。PR间期延长有显著意义,血药浓度与PR间期变化满足S 型模型,其药效学参数:EC50 64.6±16.9μg·L-1; Emax54±11ms;s 1.68±0.66。 相似文献
9.
10.
Hydrolysis of peptides within lumen of small intestine 总被引:2,自引:0,他引:2