全文获取类型
收费全文 | 2155篇 |
免费 | 96篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 39篇 |
儿科学 | 44篇 |
妇产科学 | 66篇 |
基础医学 | 331篇 |
口腔科学 | 42篇 |
临床医学 | 129篇 |
内科学 | 562篇 |
皮肤病学 | 116篇 |
神经病学 | 120篇 |
特种医学 | 67篇 |
外科学 | 297篇 |
综合类 | 1篇 |
预防医学 | 31篇 |
眼科学 | 12篇 |
药学 | 109篇 |
中国医学 | 17篇 |
肿瘤学 | 282篇 |
出版年
2023年 | 12篇 |
2022年 | 16篇 |
2021年 | 27篇 |
2020年 | 30篇 |
2019年 | 19篇 |
2018年 | 33篇 |
2017年 | 33篇 |
2016年 | 38篇 |
2015年 | 34篇 |
2014年 | 43篇 |
2013年 | 61篇 |
2012年 | 65篇 |
2011年 | 97篇 |
2010年 | 53篇 |
2009年 | 54篇 |
2008年 | 75篇 |
2007年 | 127篇 |
2006年 | 119篇 |
2005年 | 131篇 |
2004年 | 99篇 |
2003年 | 118篇 |
2002年 | 129篇 |
2001年 | 34篇 |
2000年 | 45篇 |
1999年 | 54篇 |
1998年 | 36篇 |
1997年 | 25篇 |
1996年 | 37篇 |
1995年 | 38篇 |
1994年 | 24篇 |
1993年 | 33篇 |
1992年 | 33篇 |
1991年 | 32篇 |
1990年 | 45篇 |
1989年 | 43篇 |
1988年 | 49篇 |
1987年 | 43篇 |
1986年 | 30篇 |
1985年 | 38篇 |
1984年 | 33篇 |
1983年 | 19篇 |
1982年 | 14篇 |
1981年 | 16篇 |
1980年 | 13篇 |
1979年 | 15篇 |
1978年 | 17篇 |
1977年 | 13篇 |
1975年 | 8篇 |
1969年 | 8篇 |
1968年 | 7篇 |
排序方式: 共有2265条查询结果,搜索用时 46 毫秒
1.
2.
Hiroki Sato Atsushi Watanabe Tamotsu Yamaguchi Nobuhiro Harada Akihiko Yamauchi Satomi Inoue Tomio Abe 《Annals of thoracic and cardiovascular surgery》2005,11(1):41-43
Intralobar pulmonary sequestration associated with asymptomatic aspergillosis is a rare case. We describe the case of a 65-year-old woman with intrapulmonary sequestration, anomalous systemic arterial supply to the left lower lobe and aspergillosis who underwent left lower lobectomy and ligation of an anomalous artery by Video-Assisted Thoracoscopic surgery (VATS). Pathological examination showed the parenchymal distortion and chronic inflammation. Aspergillus were found in the cyst. VATS lobectomy for intralobar pulmonary sequestration is a safe and valid procedure. 相似文献
3.
4.
5.
Hiroshi Uno Yoshihiro Izawa Kiyoshi Sagara Tamotsu Koyama Tokutaro Makita Chia-Yuan Hsu-Chang Mitsugi Sugiyama 《Journal of bone and mineral metabolism》1990,8(1):10-16
The effect of 1α-hydroxyvitamin D3 (1α(OH)D3) on the metabolic bone disorders developed in gastrectomized rats were investigated biochemically and histomorphologically.
1α(OH)D3 was suspended in 0.2 % Triton-X-100 aqueous solution after dissolving in a very small amount of ethanol, was given orally
to the rats for 10 weeks. The sham operated animals and the gastrectomy control animals received the vehicle alone. Gastrectomy
was followed by the development of the metabolic bone disorders after 10 weeks of observation. This was characterized by reduction
in ash content of the femur and histologically by a disappearance of the trabecular bone in tibial metaphysis. Decrease Ca
absorption from the intestines was demonstrated by a radiotracer technique. Biochemical studies showed significant decreases
in serum 25(OH)D concentration in gastrectomized rats. These findings suggest that gastrectomy partially impairs intestinal
absorption of calcium and results in a negative calcium balance, which may contribute to the development of bone metabolic
disorders in rats. The administration of 1α(OH)D3 increased dose-dependently serum calcium and Ca absorption from the intestine and prevented the development of bone metabolic
disorders histomorphologically. 相似文献
6.
To examine whether prostacyclin has an attenuating effect on nonspecific bronchial responsiveness in asthma, we measured provocative concentration of methacholine producing a 20% fall in forced expiratory volume in 1 second (PC20-FEV1) before and after oral administration of a chemically stable prostacyclin analog (OP-41483) (200 μg 4 times a day for 4 days) in 8 patients with stable asthma. Neither baseline pulmonary function nor PC20-FEV1 significantly improved after the treatment. These results suggest that prostacyclin may have no direct effect on bronchial responsiveness in asthmatics. Further studies using more potent and long-lasting prostacyclin mimetic will be needed to confirm the conclusion. 相似文献
7.
8.
A Kitami K Suzuki G Hori T Akizawa M Narushima E Noguchi Y Iida F Sagawa 《Nihon Kyōbu Shikkan Gakkai zasshi》1991,29(11):1505-1508
A 66-year-old woman visited our hospital for further investigation of a coin-shaped lesion in the right lower lung field. After admission, CT-scan revealed an anterior mediastinal tumor. Thymoma and lung metastasis from thymoma were suspected. At thoracotomy, an invasive thymoma involving the left phrenic nerve, the left upper lobe, and the pericardium was found, and the diagnosis of lung metastasis was made. Postoperative pathological findings showed a predominantly lymphocytic thymoma with round and oval-shaped epithelial cells, and the metastatic lung lesion revealed the same findings. Postoperative radiotherapy (4000 rads) and chemotherapy with a combination of CDDP, VDS, and CPA were administered. The metastasis of thymoma is not rare, but most often it is found after operation. In this case the diagnosis of metastatic thymoma was made pre-operatively from a solitary lung lesion. 相似文献
9.
10.
Haruhiko Ogawa Masaki Fujimura Motoyasu Saito Tamotsu Matsuda Nobuaki Akao Kaoru Kondo 《Clinical autonomic research》1994,4(1-2):19-28
Eosinophilic bronchitis without asthma can cause a persistent non-productive cough which is resistant to bronchodilator therapy. To understand the mechanism of the cough in this disorder, an animal model of eosinophilic bronchitis was developed. Guinea-pigs were treated with transnasal administration of polymyxin B or saline twice a week for 3 weeks. The number of eosinophils in bronchoalveolar lavage fluid increased in polymyxin B-treated animals when compared with those treated with saline. In addition, histological examination showed that the number of eosinophils infiltrated into the tracheal epithelium increased; injury to the tracheal epithelium was greater in polymyxin B-treated animals. The numbers of coughs induced by saline and each concentration of capsaicin (10–18, 10–16, 10–14M) were greater in the polymyxin B-treated animals. FK-224 (a neurokinin receptor antagonist) decreased the heightened cough reflex in this animal model of eosinophilic bronchitis. These findings suggest that neuropeptides, and particularly neurokinins, are involved in the heightened cough receptor sensitivity in eosinophilic bronchitis without asthma. This has implications for better understanding of this disorder and its treatment. 相似文献