全文获取类型
收费全文 | 23646篇 |
免费 | 1078篇 |
国内免费 | 133篇 |
专业分类
耳鼻咽喉 | 184篇 |
儿科学 | 359篇 |
妇产科学 | 179篇 |
基础医学 | 2998篇 |
口腔科学 | 517篇 |
临床医学 | 1673篇 |
内科学 | 6512篇 |
皮肤病学 | 373篇 |
神经病学 | 1743篇 |
特种医学 | 1144篇 |
外科学 | 4081篇 |
综合类 | 102篇 |
一般理论 | 2篇 |
预防医学 | 476篇 |
眼科学 | 423篇 |
药学 | 1395篇 |
中国医学 | 36篇 |
肿瘤学 | 2660篇 |
出版年
2023年 | 147篇 |
2022年 | 316篇 |
2021年 | 520篇 |
2020年 | 268篇 |
2019年 | 350篇 |
2018年 | 454篇 |
2017年 | 366篇 |
2016年 | 417篇 |
2015年 | 459篇 |
2014年 | 579篇 |
2013年 | 711篇 |
2012年 | 1130篇 |
2011年 | 1321篇 |
2010年 | 745篇 |
2009年 | 619篇 |
2008年 | 1083篇 |
2007年 | 1177篇 |
2006年 | 1131篇 |
2005年 | 1121篇 |
2004年 | 1088篇 |
2003年 | 1129篇 |
2002年 | 1092篇 |
2001年 | 672篇 |
2000年 | 693篇 |
1999年 | 647篇 |
1998年 | 303篇 |
1997年 | 244篇 |
1996年 | 176篇 |
1995年 | 193篇 |
1994年 | 188篇 |
1993年 | 144篇 |
1992年 | 516篇 |
1991年 | 403篇 |
1990年 | 427篇 |
1989年 | 424篇 |
1988年 | 401篇 |
1987年 | 352篇 |
1986年 | 345篇 |
1985年 | 375篇 |
1984年 | 225篇 |
1983年 | 208篇 |
1982年 | 100篇 |
1979年 | 180篇 |
1978年 | 106篇 |
1977年 | 117篇 |
1975年 | 95篇 |
1973年 | 99篇 |
1971年 | 93篇 |
1969年 | 101篇 |
1968年 | 108篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis
下载免费PDF全文
![点击此处可从《Journal of the European Academy of Dermatology and Venereology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
2.
3.
4.
5.
6.
7.
Yoshiki Imamura Takahiro Shinozaki Akiko Okada‐Ogawa Noboru Noma Masahiro Shinoda Koichi Iwata Akihiko Wada Osamu Abe Kelun Wang Peter Svensson 《Journal of oral rehabilitation》2019,46(6):574-587
Burning mouth syndrome (BMS) is a chronic oro‐facial pain disorder of unknown cause. It is more common in peri‐ and post‐menopausal women, and sex hormone dysregulation is believed to be an important causative factor. Psychosocial events often trigger or exacerbate symptoms, and persons with BMS appear to be predisposed towards anxiety and depression. Atrophy of small nerve fibres in the tongue epithelium has been reported, and potential neuropathic mechanisms for BMS are now widely investigated. Historically, BMS was thought to comprise endocrinological, psychosocial and neuropathic components. Neuroprotective steroids and glial cell line–derived neurotrophic factor family ligands may have pivotal roles in the peripheral mechanisms associated with atrophy of small nerve fibres. Denervation of chorda tympani nerve fibres that innervate fungiform buds leads to alternative trigeminal innervation, which results in dysgeusia and burning pain when eating hot foods. With regard to the central mechanism of BMS, depletion of neuroprotective steroids alters the brain network–related mood and pain modulation. Peripheral mechanistic studies support the use of topical clonazepam and capsaicin for the management of BMS, and some evidence supports the use of cognitive behavioural therapy. Hormone replacement therapy may address the causes of BMS, although adverse effects prevent its use as a first‐line treatment. Selective serotonin reuptake inhibitors (SSRIs) and serotonin and noradrenaline reuptake inhibitors (SNRIs) may have important benefits, and well‐designed controlled studies are expected. Other treatment options to be investigated include brain stimulation and TSPO (translocator protein 18 kDa) ligands. 相似文献
8.
Yamaoka Mai Yoshida Mahoko Nakashima Ayumu Doi Shigehiro Naito Takayuki Masaki Takao 《Clinical and experimental nephrology》2022,26(11):1111-1118
Clinical and Experimental Nephrology - The association between N-terminal pro-brain natriuretic peptide (NT-proBNP) and stroke in Japanese hemodialysis (HD) outpatients is unclear. Therefore, in... 相似文献
9.
Kazuhiko Abe 《The world journal of biological psychiatry》2006,7(2):70-74
Antipsychotics have been found to induce recurrent psychotic episodes lasting minutes to hours, mostly accompanied by oculogyric crisis (OGC). To characterize this side effect, antipsychotic-induced and postencephalitic OGCs that were reported in the literature were compared to find out common characteristics of OGCs and their associated symptoms. Both postencephalitic and antipsychotic-induced OGCs were found to occur late in the day and at regular intervals, and were associated with autonomic symptoms such as profuse sweating, facial flushing, transitory hypertension and difficulty in micturition. They were often associated also with transient psychiatric episodes: visual hallucinations and illusions, auditory hallucinations, delusions, catatonic phenomena, obsessive thoughts and panic attacks. These (OGC) characteristics will be useful in recognizing antipsychotic-induced psychiatric episodes. The associated psychiatric episodes were noted to recur occasionally also without OGC in a few postencephalic cases, and during gradual dose reduction or after a switch to a novel or low-potency antipsychotic in drug-induced cases. These findings suggest that episodes with the OGC characteristics but without OGC per se, may be less severe reactions to antipsychotic medication than those with OGC, and may represent manifestations of subclinical OGC. 相似文献
10.