全文获取类型
收费全文 | 414篇 |
免费 | 21篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 43篇 |
妇产科学 | 4篇 |
基础医学 | 46篇 |
口腔科学 | 4篇 |
临床医学 | 34篇 |
内科学 | 41篇 |
皮肤病学 | 2篇 |
神经病学 | 175篇 |
特种医学 | 34篇 |
外科学 | 5篇 |
综合类 | 6篇 |
预防医学 | 14篇 |
眼科学 | 3篇 |
药学 | 20篇 |
中国医学 | 1篇 |
肿瘤学 | 11篇 |
出版年
2022年 | 4篇 |
2021年 | 4篇 |
2020年 | 6篇 |
2018年 | 9篇 |
2016年 | 10篇 |
2015年 | 4篇 |
2014年 | 12篇 |
2013年 | 19篇 |
2012年 | 12篇 |
2011年 | 11篇 |
2010年 | 9篇 |
2009年 | 15篇 |
2008年 | 12篇 |
2007年 | 15篇 |
2006年 | 12篇 |
2005年 | 16篇 |
2004年 | 12篇 |
2002年 | 12篇 |
2001年 | 16篇 |
2000年 | 10篇 |
1999年 | 9篇 |
1998年 | 15篇 |
1997年 | 8篇 |
1996年 | 9篇 |
1995年 | 9篇 |
1994年 | 12篇 |
1993年 | 11篇 |
1992年 | 8篇 |
1989年 | 9篇 |
1988年 | 9篇 |
1987年 | 4篇 |
1986年 | 7篇 |
1985年 | 5篇 |
1984年 | 6篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1978年 | 5篇 |
1977年 | 5篇 |
1976年 | 8篇 |
1975年 | 7篇 |
1974年 | 6篇 |
1973年 | 3篇 |
1970年 | 6篇 |
1969年 | 5篇 |
1968年 | 5篇 |
1967年 | 3篇 |
1966年 | 5篇 |
1965年 | 3篇 |
排序方式: 共有445条查询结果,搜索用时 15 毫秒
1.
Clinical characteristics of rapidly progressive leuko-araiosis 总被引:1,自引:0,他引:1
S. Tarvonen-Schröder I. Räihä T. Kurki T. Rajala L. Sourander 《Acta neurologica Scandinavica》1995,91(5):399-404
Introduction – 38 patients found to have either pure leuko-araiosis (LA) or LA combined with infarction(s) on computer tomography (CT) in 1989 were re-examined in 1992 in order to evaluate the progression of LA. The follow-up period averaged 3.2 years. Material and methods - The clinical and radiological data on patients in 1989 were collected from hospital records and re-evaluated. The patients were re-examined clinically (including 24 hour ambulatory blood pressure measurement), and neuroradiologically (CT) in 1992 for this study. Results – 11 (29%) patients were found to have significant (rapid) progression of the extent of LA on CT during the follow-up. At baseline, there was no significant difference in the mean number of brain infarctions between the groups with progressing (prLA) and non-progressing LA (nprLA) or between the number of cortical and central infarctions within these groups. At follow-up, the total number of infarctions had increased significantly in both groups, but it was mostly because of the increase in cortical infarctions in the prLA group (p = 0.043) and, conversely, the central ones in the nprLA group (p = 0.011). prLA was found to be related to heart failure (82% vs 37%, p = 0.029) and atrial fibrillation (55% vs 19%, p = 0.047), whereas nprLA was strongly associated with a sudden onset of symptoms (78% vs prLA 18%, p = 0.001) like a-true brain infarction. Other clinical factors, including mean blood pressure and heart rate, did not clearly differentiate between the groups. Conclusion - The results suggest that there are different subgroups of patients with LA associated with various vascular factors. The occurrence of LA is not related to the distribution of infarctions. The progression of LA is not related to the number of brain infarctions or to the simultaneous increase of infarctions on CT. 相似文献
2.
Magnetic resonance (MR) imaging has been used in the temporomandibular joint (TMJ) primarily to define the disk position. This report examines altered morphology and signal intensity characteristics of the TMJ disk as they relate to the severity of internal derangement. Two hundred sixteen joints in 133 patients with a history of such derangement. were imaged with MR. Disk position, signal intensity, morphology, and the presence of osteoarthritis were determined for each joint. The normal disk was not anteriorly displaced and had a normal "bow-tie" shape. A grade 1 disk was anteriorly displaced and had a normal shape; a grade 2 disk was anteriorly displaced and had an abnormal shape. Forty (19%) joints were considered normal; none of these exhibited osteoarthritis. One hundred thirty-nine (64%) joints were grade 1; osteoarthritis was found in 17%. Thirty-seven (17%) were grade 2; osteoarthritis was found in 95%. All forty normal joints had high or intermediate signal intensity in the disk. Osteoarthritic joints had a higher percentage of disks with diminished intensity (P less than .0001). Severe or untreated osteoarthritis is known to be a complication of TMJ internal derangements; hence this grading system seems to correlate with the severity of internal derangement. 相似文献
3.
4.
5.
Sourander A Helstelä L Helenius H 《Social psychiatry and psychiatric epidemiology》1999,34(12):657-663
Background: The aim of the study is to report parent/youth self-report agreement on emotional and behavioral symptoms among 15- to 16-year-old
adolescents. Methods: A completed Child Behavior Checklist and Youth Self-Report were obtained from 580 subjects. Results: Adolescents reported significantly more problem behaviors than their parents. Adolescent girls reported a significantly
higher level of distress than boys in most symptom domains. The discrepancies between parent reports and youth self-reports
were greater, especially for internalizing symptoms, for girls than for boys. Conclusions: Many adolescents in need of psychiatric assessment do not receive appropriate help because their problems remain unnoticed
by adults. Internalizing problems among girls seem especially likely to remain unrecognized by adults.
Accepted: 21 October 1999 相似文献
6.
This register study includes all patients under 18 years in Finland discharged from psychiatric inpatient treatment in 1990
(n = 818) and 1993 (n = 958). The prevalence of children and adolescents in the population who had previously been treated was about 7–8 per 10,000.
The incidence of new cases of children and adolescents who had previously been inpatients within the last year was about 5–6
per 10,000 in this age group. The prevalence was lowest in the preschool group (about 1:10,000) and highest in the adolescent
group (about 12–14:10,000). About two-thirds of inpatients were boys. Adjustment disorders (DSM-III-R) were the most common
diagnosis both in 1990 and 1993 (about 30%). Mood and anxiety disorders were the second most frequent (19–23%) and disruptive
behaviour disorders the third most frequent (13–15%) diagnostic category. The diagnostic profiles differed largely according
to sex and age.
Accepted: 18 May 1998 相似文献
7.
Summary The internal vascularization of the brain was studied in foetuses of normal and protein-deprived rats from embryonic day (E) 12 to 15. The position of vascular branches showed distinct relations to the various zones of the neuroepithelium. The possibility that various parts of the vascular system may differ in function, maturation, and morphogenetic relations to the neuroepithelium must be considered. The distinct vascular layers were therefore given names relating them to the respective wall zone. The ingrowth of straight stem vessels from the epiparenchymal vascular plexus into the neuroepithelium and the formation of vascular branches close to the ventricular system were referred to as stage I of the internal vascularization. The resulting plexus was called the deep vascular plexus of the ventricular zone. Its formation followed the same temporospatial gradients as the formation of the marginal zone. Following the formation of the intermediate zone, more stem vessels entered the neuroepithelium and a superficial vascular plexus of the ventricular zone was formed (stage II). This plexus was positioned close to the border between the ventricular zone and the intermediate zone. Subsequently, vascular branches also formed plexuses of the intermediate and subventricular zones (stage III). No intraepithelial vessels were seen on E 12. The temporospatial gradients in the telencephalic vesicles were caudal to rostral and lateral to medial, starting in the parts corresponding to the ganglionic eminence in the floor of the lateral ventricle on E 13. Only the dorsomedial angles of the hemispheres showed no vessels on E 15.No obvious differences were seen between the normal and the protein-deprived foetuses regarding the timing and extent of vascularization or the size and appearance of wall zones in the immature central nervous (I-CNS). 相似文献
8.
Katja M. Lampi Susanna Hinkka-Yli-Salomäki Venla Lehti Hans Helenius Mika Gissler Alan S. Brown Andre Sourander 《Journal of autism and developmental disorders》2013,43(11):2526-2535
Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132), Asperger’s syndrome (n = 1,785) or other pervasive developmental disorder (PDD) (n = 1,796), which were ascertained from the Finnish Hospital Discharge Register. Controls were selected from the Finnish Medical Birth Register. Conditional logistic regression models were used for statistical analyses. Advanced paternal age (35–49 years) was associated with childhood autism in offspring, whereas advanced maternal age was associated with both Asperger’s syndrome and PDD in offspring (35 years or more and 40 years or more, respectively). Teenage motherhood (19 years or less) was associated with PDD in offspring. The main finding was that maternal and paternal ages were differentially associated with ASD subtypes. In addition to advanced parental age, teenage pregnancy seems to incur a risk for PDD in offspring. 相似文献
9.
10.