Synthesis,structure, and biological activity of derivatives of [2,2]-para-cyclophane. 1. Quaternary salts based on 4-bromoacetyl[2,2]-para-cyclophane and substituted pyridines and their fungicidal activity

Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 28, No. 3, pp. 48–51, March, 1994.     

Conversions of the antitumor drug spirobromine in solutions. I. Aqueous and hydrochloric acid solutions

Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 23, No. 6, pp. 659–664, June, 1989.     

Effects of fibrinogen on lipid peroxidation in patients with coronary heart disease and in vitro

In patients with coronary heart disease oxidizability of lipids during Cu²⁺-induced oxidation of blood plasma inversely correlated with fibrinogen content. A positive correlation was found between the amount of lipid peroxidation products in the plasma from these patients and fibrinogen content. The increase in fibrinogen content was associated with high levels of total lipids and triglycerides and low concentration of high-density lipoprotein cholesterol. In vitro experiments demonstrated that fibrinogen reduces oxidizability of blood plasma. Our results suggest that the decrease in lipid oxidizability at high concentration of fibrinogen in patients with coronary heart disease is related to predominant oxidation of fibrinogen and its competition with plasma lipids during Cu²⁺-induced oxidation.     

Physicochemical properties of membranes and functional status of liver mitochondria in rats with an inherited capacity for increased radical formation

Liver mitochondria of inbred W/SSM rats with inherited increased radical formation reveal the following anomalies: inhibition of oxidative phosphorylation, a lowered transmembrane potential, and alterations in protein-lipid interaction. The membrane viscosity and osmotic stability of mitochondria are unaffected. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N ^o 6, pp. 628–631, June, 1995