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排序方式: 共有449条查询结果,搜索用时 15 毫秒
1.
SB Miranda† O Lupi‡ E Lucas† 《Journal of the European Academy of Dermatology and Venereology》2004,18(5):622-625
Pityriasis rosea (PR) is a relatively common disease although its aetiology has not yet been identified. It occurs worldwide and there is no racial susceptibility factor. It usually affects teenagers and young adults between 10 and 35 years of age. Typical PR is much easier to diagnose than the rare atypical forms. We report a rare case of vesicular PR in a black woman who had vesicular lesions limited to her palms and soles in addition to regular typical lesions. We devised an efficient oral erythromycin treatment for this patient. 相似文献
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进一步研究了抗三尖杉酯碱的HL-60细胞(HR20)抗细胞凋亡的机制及该抗性和抗药性的关系。结果表明,环孢菌素A(CsA)20,10μg·ml ̄(-1)诱导HL-60细胞发生凋亡,而阻断HR20细胞于G_1期,就不能诱导细胞发生凋亡。低浓度的CsA明显增加柔红霉素在HR20细胞内的积聚,其逆转抗药性作用与阻断细胞周期运行无关。CsA10μg·ml ̄(-1)处理HR20细胞,可引起50kDa的蛋白质高度磷酸化。结果提示:环孢菌素A阻断抗三尖杉酯碱的HL-60细胞于G_1期,而诱导敏感的HL-60细胞发生凋亡,其阻断作用与抗药性无关 相似文献
6.
Histopathological grading of soft tissue tumours. Prognostic significance in a prospective study of 278 consecutive cases 总被引:1,自引:0,他引:1
Olaf Myhre Jensen Jrgen Hgh Svend E.
stgaard Axel Munck Nordentoft Otto Sneppen 《The Journal of pathology》1991,163(1):19-24
A consecutive 10-year series of 278 soft tissue sarcomas was prospectively graded, using a system based on the number of mitoses and taking into account parameters such as cellularity, anaplasia, necrosis, and histogenetic type and subtype of tumour. Prognostic factors in relation to metastasis-free survival were studied by uni- and multivariate analysis. Fifty-seven (20.5 per cent) were low-grade tumours, 43 (15.5 per cent) were intermediate, and 178 (64 per cent) were high grade. High-grade tumours were divided into two groups; 80 (29 per cent) grade 3A (= 5-20 mitoses per 10 high power fields (HPF)) and 78 grade 3B (28 per cent) (= more than 20 mitoses/10 HPF); 10 HPF corresponds to 2.5 mm2. Twenty (7.2 per cent) high-grade tumours could not be further subdivided. Grading was found to be the prognostic factor associated with the strongest predictive value. Five-year survival in low-grade and intermediate tumours (95 and 86 percent, respectively) differed significantly (P less than 0.0001) from high grade (50 per cent) and (p = 0.0018) between grade 3A (64 per cent) and grade 3B (41 per cent). Other prognostic indicators of importance in high-grade tumours were age, local recurrence at presentation (primary operation outside the Centre), and localization (superficial vs. deep). 相似文献
7.
Needle biopsy of renal allografts: comparison of two techniques 总被引:2,自引:0,他引:2
Bogan ML; Kopecky KK; Kraft JL; Holladay AO; Filo RS; Leapman SB; Thomalla JV 《Radiology》1990,174(1):273-275
Two techniques for renal allograft biopsy were retrospectively evaluated to compare relative safety and efficacy. After ultrasound (US) localization of the kidney and biopsy with a hand-held 14-gauge cutting needle, an adequate specimen was obtained in 74 of 77 cases (96%). Major complications occurred in six of these 77 cases (8%). One hundred four biopsies were performed by using a smaller 18-gauge cutting needle with a spring-loaded biopsy "gun" and real-time US guidance. With this newer technique, specimens adequate for diagnosis were obtained in 99 biopsies (95%). There was a single major complication with this technique (1%). The 18-gauge needle with real-time US guidance yields comparably adequate specimens with a lower frequency of complications. 相似文献
8.
Madsen F Søjbjerg JO Sneppen O 《Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.]》1994,3(1):17-23
Twenty-three consecutive patients with rheumatoid arthritis who had 26 Pritchord Mark II elbow prostheses were followed prospectively with a mean follow-up of 75 months (range 52 to 101 months). Two patients with three elbow prostheses have died, leaving 21 patients with 23 elbow prostheses for review. At the latest follow-up all the nonrevised elbows had achieved good or excellent results concerning pain relief and elbow motion. According to the data analyzed by a survivorship function-a Kaplan-Meier curve-the early results were promising with 92% of the prostheses surviving the first 5 years; however, only 43% of the prostheses have survived 8 years. Seven prostheses have been revised; the reasons for revision include one infection, one humeral fracture, one loosening of the humeral component, and four disconnections of the hinge. The number with disconnection of the hinge is increasing. Of 16 prostheses still not revised, the x-ray film reveals migration of the pin axle in six. Radiographic signs of component loosening or migration of the axle are not reflected in pain, function, or total score of the elbow. 相似文献
9.
分娩期连续电子胎心监护用于胎儿评估 总被引:1,自引:0,他引:1
1背景 在美国,每4例孕妇中有3例在产群中及分娩时使用电子胎儿监护(EFM)(NCHS1993)。1989年,美国妇产科学院(ACOG1989)发表了一项声明,对于低危妊娠既可使用EFM,也可使用间断性胎心听诊;但是,美国预防保健委员会(USPSTF1989)和加拿大的定期健康检查委员会(CTFPHE1994)对高危妊娠仍保留使用EFM。尽管有人对EFM的效果和安全性表示担忧(Thacker 1987:Thacker 1995), 相似文献
10.
SB Grover N Midha M Gupta U Sharma VH Talib 《Journal of Medical Imaging and Radiation Oncology》2005,49(2):175-178
The clinical manifestations of chronic disseminated histoplasmosis are non-specific and resemble those of other chronic infections and malignancies. We report the radiographic, sonographic and contrast-enhanced CT appearances of histoplasmosis in an adult male with non-insulin dependent diabetes mellitus, who was HIV negative and presented with weight loss and pyrexia. Imaging studies simulated tuberculosis with mediastinal lymphadenopathy, bilateral fibrotic lung lesions, hepatomegaly and bilateral hypoattenuating adrenal enlargement, without clinical or laboratory evidence of hypoadrenalism. Computed tomography-guided fine-needle aspiration biopsy of adrenal glands revealed Histoplasma capsulatum. We report our experience to increase awareness of the imaging spectrum of disseminated histoplasmosis and its similarity to tuberculosis as, with increasing incidence of AIDS, the chances of these infections are likely to increase. Moreover, awareness of this entity is important because it is known that untreated disseminated histoplasmosis is fatal. 相似文献