全文获取类型
收费全文 | 1026篇 |
免费 | 68篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 46篇 |
妇产科学 | 7篇 |
基础医学 | 132篇 |
口腔科学 | 20篇 |
临床医学 | 195篇 |
内科学 | 164篇 |
皮肤病学 | 18篇 |
神经病学 | 32篇 |
特种医学 | 195篇 |
外科学 | 104篇 |
综合类 | 43篇 |
预防医学 | 35篇 |
眼科学 | 3篇 |
药学 | 50篇 |
肿瘤学 | 29篇 |
出版年
2019年 | 9篇 |
2017年 | 8篇 |
2016年 | 15篇 |
2015年 | 12篇 |
2014年 | 28篇 |
2013年 | 27篇 |
2012年 | 19篇 |
2011年 | 22篇 |
2010年 | 20篇 |
2009年 | 26篇 |
2008年 | 23篇 |
2007年 | 32篇 |
2006年 | 22篇 |
2005年 | 25篇 |
2004年 | 29篇 |
2003年 | 31篇 |
2002年 | 18篇 |
2001年 | 25篇 |
2000年 | 12篇 |
1999年 | 33篇 |
1998年 | 44篇 |
1997年 | 52篇 |
1996年 | 41篇 |
1995年 | 42篇 |
1994年 | 28篇 |
1993年 | 31篇 |
1992年 | 19篇 |
1991年 | 26篇 |
1990年 | 20篇 |
1989年 | 22篇 |
1988年 | 29篇 |
1987年 | 26篇 |
1986年 | 24篇 |
1985年 | 25篇 |
1984年 | 11篇 |
1983年 | 15篇 |
1982年 | 22篇 |
1981年 | 19篇 |
1980年 | 26篇 |
1979年 | 9篇 |
1978年 | 18篇 |
1977年 | 28篇 |
1976年 | 16篇 |
1975年 | 14篇 |
1974年 | 6篇 |
1973年 | 5篇 |
1972年 | 7篇 |
1971年 | 6篇 |
1969年 | 6篇 |
1965年 | 5篇 |
排序方式: 共有1111条查询结果,搜索用时 31 毫秒
1.
2.
Anti-estradiol immunoperoxidase labeling of nuclei, not cytoplasm, in paraffin sections, determines estrogen receptor status of breast cancer 总被引:1,自引:0,他引:1
J C O'Keane E Okon K Moroz B Burke K Sheahan M J O'Brien 《The American journal of surgical pathology》1990,14(2):121-127
We evaluated a commercially available polyclonal antibody to 17 beta-estradiol as the basis for an estrogen receptor (ER) assay of breast carcinoma in formalin-fixed paraffin tissues and then compared it with both the ER-ICA antibody in serial paraffin sections and the biochemical assay of corresponding fresh tissue. Using the estradiol antibody, 49 of 50 cases showed some cytoplasmic staining; 38 cases had nuclear staining. Sensitivity and specificity for different proportions of positive nuclear and cytoplasmic staining were calculated using receiver-operator characteristic curves. The optimum correlation with the biochemical assay was obtained with nuclear staining alone. Greater than 30% nuclear positivity as a cut-off point yielded a sensitivity of 76% and a specificity of 82%. The corresponding ER-ICA values in 38 cases yielded a sensitivity of 93% and a specificity of 56%. The methodology for the ER-ICA assay was more technically demanding in paraffin sections than that of the estradiol antibody and considerably more expensive. This study is the first to show that with nuclear staining only, and not cytoplasmic staining, as the parameter of positivity, the immunocytochemical assay of ER with anti-17 beta-estradiol antibody in routinely processed, formalin-fixed, archival material is an accurate and specific method for the determination of the ER status of breast carcinoma. 相似文献
3.
4.
Prior studies have shown that pneumothorax is one of the more difficult entities to diagnose with digitized radiography. This study was designed to test whether increasing resolution from 1.25 to 2.5 line pairs per millimeter (lp/mm) and image processing (edge enhancement from unsharp masking) would increase accuracy and confidence in the diagnosis of pneumothorax, as well as normal cases and other forms of lung disease. Conventional radiographs were digitized with use of a laser reader and then reformatted as film hard copy. Eleven observers read 35 cases reformatted in three different ways (1.25 lp/mm, 2.5 lp/mm, 1.25 lp/mm unsharp mask). The images with finer resolution (2.5 lp/mm) and unsharp mask images were superior to those with coarser resolution (1.25 lp/mm) for the diagnosis of pneumothorax. There was no difference in diagnostic accuracy for normal patients. For abnormalities other than pneumothorax, the unsharp mask images were significantly worse. Confidence in the diagnosis of pneumothorax and other abnormalities was highest with the finest resolution (2.5 lp/mm). 相似文献
5.
6.
导数光谱系数倍率法测定多组分体系感冒清胶囊中盐酸吗啉胍的含量 总被引:1,自引:0,他引:1
This paper provides a basic principle and experimental technique of derivative signal multiplier spectrophotometry in multicomponent mixture. A microcomputer was used to process the spectral data measured on a manual spectrophotometer (UV-7520) for the determination of moroxydine hydrochloride in Gan Mao Qing capsules. Quantitative analysis of multicomponent mixture can be done without sample separation. The selection of optimal wavelength pairs is performed through the program with a computer. The method needs no special spectrophotometer and is simple, rapid and easy to operate. The mean recovery was 99.98 +/- 0.53% (n = 12). 相似文献
7.
Primary Prevention of Sudden Cardiac Death in Heart Failure: Will the Solution Be Shocking? 总被引:10,自引:0,他引:10
Barry F Uretsky MD Richard G Sheahan MD 《Journal of the American College of Cardiology》1997,30(7):1589-1597
Sudden cardiac death (SCD) may occur in as many as 40% of all patients who suffer from heart failure. This review describes the scope of the problem, risk factors for SCD, the effect of medications used in heart failure on SCD and the potential effect of the implantable cardioverter-defibrillator in primary prevention. 相似文献
8.
9.
Application of reflectance spectroscopy to the estimation of uric acid, urea and glucose: an evaluation of the Ames Seralyzer
下载免费PDF全文
![点击此处可从《Journal of clinical pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
An original approach to the measurement of analytes in clinical chemistry has now become available, in which dry reagent strip technology is linked to measurement by reflectance spectroscopy. The present studies have evaluated the performance of the first of these test systems—for uric acid, urea and glucose, in serum—by comparison with conventional liquid chemistry methods. Satisfactory performance in terms of both precision and accuracy was obtained for all three test systems, the current “state-of-the-art” performance criteria being met; the Seralyzer system proved reliable and easy to use in the hands of trained operators. It should find a place as a “Stat” analyser in the laboratory, in specified wards and in Health Centres. 相似文献
10.
Pathogenesis of Escherichia coli diarrhea 总被引:56,自引:0,他引:56