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排序方式: 共有437条查询结果,搜索用时 15 毫秒
1.
全层缝合在预防阑尾炎术后切口感染中的应用 总被引:4,自引:0,他引:4
目的:探讨全层缝合在预防阑尾炎术后切口感染的治疗效果。方法:将皮肤、皮下组织、腹外斜肌腱膜全层褥式缝合(腹膜不予缝合)。结果:56例患者无一例感染,也未发现近期并发症。结论:此方法对预防切口感染有较好疗效,且能缩短手术时间,操作简单,建议值得临床应用。 相似文献
2.
267株烧伤感染细菌的调查分析 总被引:1,自引:0,他引:1
目的:回顾性分析1995年1月至2003年12月间本院烧伤科细菌分布和菌种耐药情况,以指导临床合理用药。方法:收集烧伤病人创面分泌物、血液、痰液及静脉导管末端行普通细菌培养,统计细菌分布情况及常用药物的敏感性。结果:9年来共检出19种267株细菌.其中铜绿假单胞菌和金黄葡萄球菌占83.14%,并有逐渐增加的趋势。铜绿假单胞菌以亚胺培南、头孢哌酮/舒巴坦和多粘菌素B最敏感;氨曲南亦较敏感,且敏感性呈逐渐上升趋势。金黄色葡萄球菌以万古霉素最敏感.呋喃妥因、利福平次之,青霉素类和大部分头孢菌素则高度耐药。结论:目前烧伤感染仍以铜绿假单胞菌和金黄色葡萄球菌为主.防治该两种细菌感染是抗烧伤感染的主要任务。 相似文献
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Astrid LA. Kuijpers Rolph Pfundt Patrick LJM Zeeuwen Henri OF. Molhuizen Edwin CM. Mariman Peter CM. van de Kerkhof Joost Schalkwijk 《Clinical genetics》1998,54(1):96-101
Psoriasis is a multifactorial skin disease characterised by epidermal abnormalities and infiltration by lymphocytes and polymorphonuclear leukocytes (PMN). Skin-derived antileukoproteinase (SKALP), also known as elafin, is a potent inhibitor of human leukocyte elastase and proteinase 3, two PMN-derived proteinases implicated in tissue destruction and leukocyte migration. We have shown that, at least at the protein level, SKALP is significantly decreased in lesional skin of patients with pustular psoriasis compared with plaque-type psoriasis. This finding raised the possibility that SKALP could be one of the candidate genes for pustular forms of psoriasis. We therefore performed single strand conformation polymorphism (SSCP) analysis on the SKALP gene to screen for mutations/polymorphisms in the exons of 30 patients with plaque-type psoriasis, 15 patients with pustular psoriasis and 48 healthy controls. In exon 1 a polymorphism was detected at position + 43 relative to the translation start site, resulting in a substitution of threonine for alanine in the signal peptide. In the promoter region a dinucleotide repeat polymorphism was identified. Both polymorphisms were not associated with pustular psoriasis, or psoriasis in general. Our data indicate that the decrease in SKALP activity in pustular psoriasis is not caused by mutations in the coding region of the gene, and that there is no allelic association between pustular psoriasis and SKALP gene polymorphisms. 相似文献
5.
Wieslaw W. Pawlik Piotr Gustaw Eugene D. Jacobson Ryszard Sendur Krzysztof Czarnobilski 《Pflügers Archiv : European journal of physiology》1995,429(3):301-305
It has long been recognized that intestinal blood flow increases at mealtimes. Mesenteric hyperaemia is also evoked by activation of sensory peptidergic nerves. Our studies explored the possible role of endogenous nitric oxide (NO) in the rat intestinal vasodilator response to luminal instillation of an oleic acid plus bile mixture before and after acute intrajejunal instillation of capsaicin and after chronic pretreatment with capsaicin. In anaesthetized rats we measured jejunal blood flow (BF) with an ultrasonic Doppler flowmeter and systemic arterial pressure (AP) with a pressure transducer. Intestinal perfusion with 80 mM oleic acid in bile increased BF by 98±12%. Instillation of 4 mg of capsaicin into the jejunal lumen initially increased BF by 42±9% but was followed by vasoconstriction. Inhibition of NO synthase with 25 mg/kg i.v. N-nitro-L-arginine (L-NNA) decreased BF by 27±5% and increased AP by 37±11%. After treatment with L-NNA and after acute and chronic administration of capsaicin, the bile-oleate-induced maximal increases in BF above control levels were 42±7%, 65±12%, and 58±8%, respectively. The observed inhibitory effect of L-NNA on the intestinal hyperaemic response to the bile-oleate mixture was reversed by pretreatment with L-arginine (100 mg/kg i.V.). In capsaicin pretreated rats the subsequent bile-oleate-induced hyperaemia was reduced in magnitude but the inhibitory effects of L-NNA were proportionately the same as in animals not receiving capsaicin. These findings support the hypothesis that NO is involved with bile-oleate-induced mesenteric hyperaemia. 相似文献
6.
目的探讨经阴道、会阴超声诊断直肠肿瘤的临床价值。方法直肠灌水后经阴道、会阴超声检查直肠肿瘤病人28例,并与正常人20例,直肠腔内超声16例对照,同时5例肿瘤作了标本超声检查。结果 28例患者中,26例检出直肠肿瘤28个,其部位在距肛门口2.5~15cm范围内,2例经阴道、会阴超声未发现肿瘤。直肠灌水后经阴道会阴超声检查可直观显示肿瘤的形态,与标本超声显示一致;其病理分期的符合率分别为80.8%。发现淋巴结肿大5例。尤其对高位直肠肿瘤或肿瘤致直肠严重狭窄的病例或Miles手术后,更具有价值。结论经阴道、会阴超声可作为直肠肿瘤检查的补充方法。 相似文献
7.
WEINBERG JULIUS; GRIMAUD OLIVIER; NEWTON LISA; ON BEHALF OF THE CHARTER GROUP 《European journal of public health》1999,9(3):236-240
Background: Several collaborations in communicable disease surveillancehave developed between European Union member states. Involvementin these activities takes time and money. It is vital that collaborationsare established in areas most likely to be beneficial. An exercisewas undertaken to inform national surveillance centres and theEuropean Commission as to priority areas for the developmentof collaborations. Methods: A modified Delphi exercise was undertakenamongst the heads of centres with responsibilities for surveillanceat national level in the member states of the EU. Participantsdeveloped, agreed and ranked criteria for developing collaborations.A list of communicable diseases and syndromes was then rankedusing a Likert-type scale. Three rounds were undertaken. Betweenrounds, scores and a ranking were fed back showing where participantshad ranked items, compared to the overall mean and rank distribution.For the third round participants were asked to use a categoricalscale, nominating six or ten high priority disease areas. Results:Response rates were 87.5% for round 1, 44% round 2 and 87% round3. The low round 2 response rate appeared to be because respondentsdid not wish to alter their rankings. The six high priorityareas were outbreaks of gastroenteritis/food poisoning, CID/otherslow virus infections, serious imported diseases, legionellosis,antimicrobial resistance and tuberculosis. When participantsgave ten high priority areas meningococcal disease, travel advice,vaccination/immunization and influenza were also included. Thefinal lists were accepted at the meeting of participants. Conclusions:The process was successful in developing both a priority listand consensus. 相似文献
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