全文获取类型
收费全文 | 752篇 |
免费 | 48篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 22篇 |
妇产科学 | 13篇 |
基础医学 | 123篇 |
口腔科学 | 5篇 |
临床医学 | 66篇 |
内科学 | 185篇 |
皮肤病学 | 9篇 |
神经病学 | 52篇 |
特种医学 | 45篇 |
外科学 | 81篇 |
综合类 | 6篇 |
一般理论 | 2篇 |
预防医学 | 97篇 |
眼科学 | 24篇 |
药学 | 33篇 |
肿瘤学 | 34篇 |
出版年
2023年 | 5篇 |
2022年 | 19篇 |
2021年 | 29篇 |
2020年 | 18篇 |
2019年 | 27篇 |
2018年 | 22篇 |
2017年 | 21篇 |
2016年 | 16篇 |
2015年 | 28篇 |
2014年 | 33篇 |
2013年 | 33篇 |
2012年 | 46篇 |
2011年 | 62篇 |
2010年 | 38篇 |
2009年 | 36篇 |
2008年 | 51篇 |
2007年 | 52篇 |
2006年 | 51篇 |
2005年 | 50篇 |
2004年 | 34篇 |
2003年 | 27篇 |
2002年 | 30篇 |
2001年 | 9篇 |
2000年 | 17篇 |
1999年 | 11篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1995年 | 2篇 |
1994年 | 1篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1991年 | 6篇 |
1990年 | 4篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 4篇 |
1986年 | 3篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1972年 | 3篇 |
排序方式: 共有804条查询结果,搜索用时 16 毫秒
1.
2.
3.
H. Triki D. Rezig O. Bahri N. Ben Ayed A. Ben Yahia A. Sadraoui S. Ayed 《Clinical microbiology and infection》2007,13(2):176-182
This study reports the genetic characteristics of coxsackievirus A24 isolates from Tunisia, including a coxsackievirus A24 variant (CVA24v) that caused an outbreak of acute haemorrhagic conjunctivitis (AHC) between September and November 2003. The virus genome was detected by PCR from conjunctival swabs obtained from patients with AHC. Four virus isolates were obtained from PCR-positive samples and were serotyped by sequence analysis of the VP1 and VP4 genomic region and by seroneutralisation. Phylogenetic analysis of the VP1, VP4 and 3C genomic regions was performed. Other Tunisian CVA24 isolates from paralytic cases and healthy individuals were also amplified, sequenced and included in the phylogenetic analysis. The epidemic strain belonged to the CVA24 serotype. Phylogenetic analysis of the 3C region of the genome revealed a strong relationship between the Tunisian epidemic strain and strains that caused outbreaks in Korea (2002) and Guadeloupe and French Guiana (2003). Phylogenetic analysis of the VP1 and VP4 regions showed a clear distinction between serotype CVA24 isolates from conjunctivitis and non-conjunctivitis cases. This is the first study to report an outbreak of AHC caused by CVA24v in the North African region. 相似文献
4.
Seema Irfan Mohammad Zeeshan Salima Rattani Joveria Farooqi Sadia Shakoor Rumina Hasan Afia Zafar 《Emerging infectious diseases》2021,27(3):936
We evaluated Salmonella enterica serotype Typhi strains isolated from all body sites in Pakistan during 2013–2018. Despite an increase in overall number of localized, extensively drug-resistant Salmonella Typhi in organ infections during 2018, there was no increase in the proportion of such isolates in comparison with non–extensively drug-resistant isolates. 相似文献
5.
BackgroundTo perform the citation and content analysis of 100 articles on Hallux valgus from the most cited to the least.Materials and methodsArticles published on Hallux valgus between 1980 and 2020 were analyzed by making use of the Web of Science database. Articles were ranked from most cited to the least. Content analysis of all articles was also carried out. Original research articles, reviews, and clinical trials were included in the study whereas case reports were excluded from the study.ResultsThe total number of citations of the 100 most-cited articles was 7,697. The most-cited article was ‘Prevalence of hallux valgus in the general population; systematic review and meta-analysis’ published by Sheere Nix in Journal of Foot and Ankle Research in 2010. The country where the articles were mostly produced was USA (n = 46). The most interesting issue was the osteotomy techniques and changes in Hallux valgus surgery.ConclusionThe treatment of the Hallux valgus disease is still discussed today. Citation analyses have shown that surgical developments related to HV surgery still attract attention, and this information will be updated continuously in line with the increasing number of articles. 相似文献
6.
Jeon‐Hor Chen Wei‐Fan Pan Julian Kao Jocelyn Lu Li‐Kuang Chen Chih‐Chen Kuo Chih‐Kai Chang Wen‐Pin Chen Christine E. McLaren Shadfar Bahri Rita S. Mehta Min‐Ying Su 《NMR in biomedicine》2013,26(12):1705-1713
The aim of this study was to evaluate the change of breast density in the normal breast of patients receiving neoadjuvant chemotherapy (NAC). Forty‐four breast cancer patients were studied. MRI acquisition was performed before treatment (baseline), and 4 and 12 weeks after treatment. A computer‐algorithm‐based program was used to segment breast tissue and calculate breast volume (BV), fibroglandular tissue volume (FV), and percent density (PD) (the ratio of FV over BV × 100%). The reduction of FV and PD after treatment was compared with baseline using paired t‐tests with a Bonferroni–Holm correction. The association of density reduction with age was analyzed. FV and PD after NAC showed significant decreases compared with the baseline. FV was 110.0 ml (67.2, 189.8) (geometric mean (interquartile range)) at baseline, 104.3 ml (66.6, 164.4) after 4 weeks (p < 0.0001), and 94.7 ml (60.2, 144.4) after 12 weeks (comparison with baseline, p < 0.0001; comparison with 4 weeks, p = 0.016). PD was 11.2% (6.4, 22.4) at baseline, 10.6% (6.6, 20.3) after 4 weeks (p < 0.0001), and 9.7% (6.2, 17.9) after 12 weeks (comparison with baseline, p = 0.0001; comparison with 4 weeks, p = 0.018). Younger patients tended to show a higher density reduction, but overall correlation with age was only moderate (r = 0.28 for FV, p = 0.07, and r = 0.52 for PD, p = 0.0003). Our study showed that breast density measured from MR images acquired at 3T MR can be accurately quantified using a robust computer‐aided algorithm based on non‐parametric non‐uniformity normalization (N3) and an adaptive fuzzy C‐means algorithm. Similar to doxorubicin and cyclophosphamide regimens, the taxane‐based NAC regimen also caused density atrophy in the normal breast and showed reduction in FV and PD. The effect of breast density reduction was age related and duration related. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
7.
B. Trad H. Ben Hassine M. Khalifa N. Idriss F. Slama F. Bahri C. Laouani kechrid J. Boukadida R. Sghiri 《Pathologie-biologie》2013,61(3):113-116
ObjectivesThe presence of a wide variety of autoantibodies is a characteristic feature of systemic lupus erythematosus (SLE). Although non-specific, anti-complement C1q (anti-C1q) were shown to correlate with the occurrence of active nephritis. The present study aimed to investigate the prevalence of anti-C1q in Tunisian SLE patients and their association with clinical manifestations, especially renal involvement.Patients and methodsIgG anti-C1q antibodies were assessed by Elisa in 98 SLE patients, 55 patients with rheumatoid arthritis (RA) and 65 healthy individuals (HI).ResultsAnti-C1q were found in 53 (54.1%) patients with SLE, three (5%) patients with RA and six (9.3%) HI. Among the 65 patients with renal involvement, anti-C1q were present in 35 (53.8%) patients. There was no significant association between anti-C1q and renal or extrarenal manifestations. In addition, there was no correlation between anti-C1q titer and SLEDAI index. Anti-C1q were significantly associated with anti-nucleosome (P = 0.001), anti-Sm (P = 0.01) and a low C4 level (P = 0.046). Concomitant presence of anti-C1q and anti-dsDNA antibodies was not associated with renal manifestations.ConclusionOur study shows that prevalence of anti-C1q was comparable with that previously reported in Caucasian populations. These antibodies were associated with a low C4 level. However, there was no association between anti-C1q and renal involvement or severity of nephritis. 相似文献
8.
9.
Michael Bauer Uwe Kölsch Renate Krüger Nadine Unterwalder Karin Hameister Fabian Marc Kaiser Aglaia Vignoli Rainer Rossi Maria Pilar Botella Magdalena Budisteanu Monica Rosello Carmen Orellana Maria Isabel Tejada Sorina Mihaela Papuc Oliver Patat Sophie Julia Renaud Touraine Thusari Gomes Kirsten Wenner Xiu Xu Alexandra Afenjar Annick Toutain Nicole Philip Aleksandra Jezela-Stanek Ludwig Gortner Francisco Martinez Bernard Echenne Volker Wahn Christian Meisel Dagmar Wieczorek Salima El-Chehadeh Hilde Van Esch Horst von Bernuth 《Journal of clinical immunology》2015,35(2):168-181
10.
Burin Karsl Kamil nce Nevzat Gnder Bahri Bozgeyik Volkan Klnolu 《Indian Journal of Orthopaedics》2021,55(3):688
BackgroundThe coexistence of supracondylar humerus fracture and forearm fracture is a rare trauma (3–13%) and it is called floating elbow. The aim of this study is to clinically compare the treatment outcomes of the patients diagnosed with floating elbow who underwent surgical treatment and who were followed up forearm with immobilization with splint.Materials and MethodsWhen scanned retrospectively, 60 patients who were treated with the diagnosis of floating elbow due to traumatic causes and followed up for at least 1 year were included in our study. Surgical treatment was performed on 42 patients for forearm fracture. Eighteen patients followed up with immobilization with a long arm splint. The results were evaluated according to the criteria modified by Templeton and Graham, in comparison with the patient’s intact side.ResultsIn the patients whose forearms were followed up conservatively, the mean age was 5.67 ± 2.25 years, and the mean follow-up period was 62.17 ± 45.91 months. In the patients who underwent surgery for the forearm, the mean age was 8.79 ± 2.01 years, and the mean follow-up was 47.14 ± 34.25 months. Eighteen patients whose forearms followed up conservatively, 12 had excellent and good clinical results and 6 had poor and moderate clinical results. Excellent and good clinical results in 27 patients who underwent surgical treatment for their forearms, moderate and poor clinical results obtained in 15 of them. There was no significant difference between the two groups (p = 0.357).ConclusionsIn conclusion, satisfactory clinical and radiological outcomes can be obtained with immobilization of the forearm fracture with splint, if acceptable reduction can be provided for the forearm following fixation of the supracondylar humerus fracture with the K-wire for treatment of floating elbow injury. 相似文献