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Shirwadkar CG Samant R Sankhe M Deshpande R Yagi S Schuster FL Sriram R Visvesvara GS 《Emerging infectious diseases》2006,12(6):984-986
We report a fatal case of encephalitis caused by Acanthamoeba in a 24-year-old woman from India with systemic lupus erythematosus. Diagnosis was made by identification of amebas in brain sections by immunofluorescence analysis and confirmed by demonstrating Acanthamoeba mitochondrial 16S rRNA gene DNA in brain tissue sections. 相似文献
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It is well known that giant cell tumours of the bone rarely occur below the age of 20 years. Many radiologists and orthopaedicians do not even consider giant cell tumours as a differential diagnosis from a lytic lesion before epiphyseal closure. This is a rare case report of a 14-year-old girl with proven giant cell tumour of the epiphysis of the distal femur. 相似文献
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Abhijeet Botre Vrajesh Udani Neelu Desai Spoorthy Jagadish Milind Sankhe 《Indian pediatrics》2017,54(8):678-680
Background
Management of refractory status epilepticus in children is extremely challenging.Case characteristics
Two children with medically refractory status epilepticus, both of whom had lesional pathology on MRI and concordant data on EEG and PET scan.Intervention
Emergency hemispherotomy performed in both patients. A complete, sustained seizure freedom obtained postoperatively.Message
Emergency surgery is a treatment option in selected cases of drug refractory status epilepticus with lesional pathology and concordant data.8.
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Jagtap VS Acharya SV Sarathi V Lila AR Budyal SR Kasaliwal R Sankhe SS Bandgar TR Menon PS Shah NS 《Pituitary》2012,15(2):243-250
Certain pituitary imaging abnormalities are a specific indicator of hypopituitarism. The objective of this study is to compare phenotypical features with radiological findings in patients with congenital growth hormone deficiency (GHD). Magnetic Resonance imaging (MRI) was performed in 103 patients [72 with Isolated GHD (IGHD) and 31 with Combined Pituitary Hormone Deficiency (CPHD)]. Images were assessed for the following abnormalities: (1) small/absent anterior pituitary, (2) thin or interrupted pituitary stalk (PSA), and (3) Ectopic posterior pituitary (EPP), and (4) others. Radiological findings were correlated with the clinical and biochemical parameters. MRI abnormalities were observed in 48.6% patients with IGHD, 93.5% with CPHD. Jaundice, hypoxia, hypoglycemia and breech deliveries were more common in EPP/PSA group. EPP/PSA was observed in 87.1% patients with severe GHD (peak GH?<?3???g/L) as compared to 12.9% with mild to moderate GHD (peak GH: 3?C10???g/L). Amongst CPHD, EPP/PSA was present in 80% of subjects with associated hypocortisolism?±?hypothyroidism as compared to 18.2% of subjects with hypogonadism. Over a mean follow up period of 4.5?years, 5.4% of subjects with IGHD and abnormal MRI progressed to CPHD while none of those with normal MRI progressed. This study emphasizes a significant clinico-radiological correlation in Asian Indian GHD patients. MRI abnormalities in the hypothalamic pituitary area, especially EPP/PSA are more common in patients with CPHD and severe GHD. Among CPHD, EPP/PSA predicts association with hypothyroidism or hypocortisolism. IGHD with MRI abnormality may evolve into CPHD. 相似文献
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