全文获取类型
收费全文 | 257篇 |
免费 | 12篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 2篇 |
妇产科学 | 7篇 |
基础医学 | 48篇 |
临床医学 | 15篇 |
内科学 | 34篇 |
皮肤病学 | 37篇 |
神经病学 | 5篇 |
外科学 | 17篇 |
预防医学 | 66篇 |
眼科学 | 7篇 |
药学 | 20篇 |
肿瘤学 | 9篇 |
出版年
2023年 | 1篇 |
2022年 | 9篇 |
2021年 | 19篇 |
2020年 | 2篇 |
2019年 | 10篇 |
2018年 | 10篇 |
2017年 | 2篇 |
2016年 | 5篇 |
2015年 | 10篇 |
2014年 | 12篇 |
2013年 | 14篇 |
2012年 | 30篇 |
2011年 | 23篇 |
2010年 | 13篇 |
2009年 | 12篇 |
2008年 | 20篇 |
2007年 | 22篇 |
2006年 | 13篇 |
2005年 | 21篇 |
2004年 | 8篇 |
2003年 | 7篇 |
2002年 | 5篇 |
2000年 | 1篇 |
排序方式: 共有269条查询结果,搜索用时 15 毫秒
1.
Rym Afiouni Josiane Helou Stephanie Matar Roland Tomb 《The Journal of clinical and aesthetic dermatology》2021,14(2):22
Rosacea and cutaneous lupus erythematosus (CLE) are chronic inflammatory dermatoses. To our knowledge, no cases of granulomatous rosacea (GR) associated with CLE have been previously reported in the literature. We describe the case of a 38-year-old female patient who presented to our clinic with a diffuse scaly facial erythema, with the codiagnoses of GR and CLE later confirmed with clinicopathological correlation. 相似文献
2.
Mejri Nesrine Rym Sellami Raoudha Doghri Hela Rifi Henda Raies Amel Mezlini 《中国肿瘤临床(英文版)》2012,(4):274-276
This paper reports a case of testicular synovial sarcoma with molecular genetic analysis.A 24-year-old male presented with painless scrotal mass.Ultrasonography showed a heterogeneous mass of 66 mm×34 mm in size involving the inguinal region.Histological examination of a surgical biopsy showed a gradeⅢmonophasic growth pattern of spindle cell proliferation.Immunohistochemical analyses indicated positive staining for pancytokeratine and epithelial membrane antigen.Cytogenetic analysis showed the presence of CYT-SSX1 mutation,and CT scan showed non-specific pleural micro-nodules with a size of 7.5 mm.The patient had an extended left orchidectomy but was lost to follow-up for 1 year.A local recurrent scrotal mass of 32 mm×25 mm,multiple inguinal lymph nodes,and increased pleural nodules,which were confirmed by histological examination,were treated with three cycles of adriamycine and ifosfamide chemotherapy,surgical resection,and radiotherapy with complete response.After 3 months,the patient developed local recurrence and pulmonary metastases that did not respond to second-line chemotherapy based on gemcitabine and paclitaxel.The patient had dyspnea at the time of this writing and chest pain,and is under third-line chemotherapy based on Deticene after 30 months of following up.This patient died on November 16,2012 after a resperatory failure and malignant plural effusion. Synovial sarcoma should be considered in the differential diagnosis of soft tissue tumor and it should be aggressively treated to improve prognosis.Although our patient has shown numerous factors of bad prognosis,he has had a relatively long survival time. 相似文献
3.
4.
Ouali S Ben Salem H Gribaa R Kacem S Hammas S Fradi S Neffeti E Remedi F Boughzela E 《Annales de cardiologie et d'angeiologie》2012,61(1):42-48
Despite clinical importance of ventricular repolarisation, it remains difficult to analyse. Conventionally, quantification of the electrocardiographic ventricular repolarization is usually performed with reference to axis of the T wave and QT interval duration. A variety of factors can prolong the QT interval, such as drug effects, electrolyte imbalances, and myocardial ischemia. The biggest risk with prolongation of the QT interval is the development of torsades de pointes. Commonly accepted reference ranges for the electrocardiogram (ECG) have been in use, with little change, for many years. Populations throughout the world present several differences: age, ethnic compositions, and are exposed to different environmental factors. Recent studies have reported reference data for QT interval in healthy population and have evaluated the influence of age, gender, QRS duration and heart rate on this interval. In this review, we address several issues relative to the measurement, and interpretation of QT interval and its adjustment for rate, age, gender and QRS duration. 相似文献
5.
6.
Sellami-Dhouib R Mrad K Sassi S Driss M Abbes I Mounir H Noureddine L Ammar B Ben Romdhane K 《Annales de pathologie》2007,27(3):247-250
Inflammatory pseudotumor (IPT) of the spleen is an uncommon entity with debated etiology, characterized by a mixture of inflammatory cells and a component of myofibroblastic spindle cells. This lesion needs to be distinguished from the follicular dendritic cell tumor and the inflammatory myofibroblastic tumor. We report two cases of splenic PTI in a 69-year old and a 62-year old women. The tumors measured respectively 80 and 30 mn in greatest dimension. An inflammatory pseudotumor was histopathologically diagnosed following a splenectomy. 相似文献
7.
Imen Chaabani Jed Bouguila Rym Kammoun Raja Chebbi Badreddine Sriha Habib Khochteli Touhami Ben Alaya 《Clinical Case Reports》2022,10(1)
We present two cases of AOT, the first case concerns a 23‐year‐old patient with an AOT located in the maxilla and the second case involves a 37‐year‐old patient presenting an AOT with mandibular localization. 相似文献
8.
Uveal effusion syndrome describes serous detachments of the choroid and ciliary body with exudative retinal detachment. It is a complication following glaucoma filtering surgeries such as trabeculectomy especially in nanophthalmic eyes.We report a rare case of a 42-year-old-woman, with nanophtalmos, who developed posterior serous retinal detachment and uveal effusions after trabeculectomy for chronic angle closure glaucoma.The patient was put on oral steroids with good clinical outcome. Anterior Segment OCT allowed monitoring of iridocorneal angle and anterior chamber depth, Swept Source OCT was useful for monitoring retinal reattachment and choroidal thickness. 相似文献
9.
Anissa Chouikha Wasfi Fares Asma Laamari Sondes Haddad-Boubaker Zeineb Belaiba Kais Ghedira Wafa Kammoun Rebai Kaouther Ayouni Marwa Khedhiri Samar Ben Halima Henda Krichen Henda Touzi Imen Ben Dhifallah Fatma Z. Guerfali Chiraz Atri Saifeddine Azouz Oussema Khamessi Monia Ardhaoui Mouna Safer Nissaf Ben Alaya Ikram Guizani Rym Kefi Mariem Gdoura Henda Triki 《Viruses》2022,14(3)
Documenting the circulation dynamics of SARS-CoV-2 variants in different regions of the world is crucial for monitoring virus transmission worldwide and contributing to global efforts towards combating the pandemic. Tunisia has experienced several waves of COVID-19 with a significant number of infections and deaths. The present study provides genetic information on the different lineages of SARS-CoV-2 that circulated in Tunisia over 17 months. Lineages were assigned for 1359 samples using whole-genome sequencing, partial S gene sequencing and variant-specific real-time RT-PCR tests. Forty-eight different lineages of SARS-CoV-2 were identified, including variants of concern (VOCs), variants of interest (VOIs) and variants under monitoring (VUMs), particularly Alpha, Beta, Delta, A.27, Zeta and Eta. The first wave, limited to imported and import-related cases, was characterized by a small number of positive samples and lineages. During the second wave, a large number of lineages were detected; the third wave was marked by the predominance of the Alpha VOC, and the fourth wave was characterized by the predominance of the Delta VOC. This study adds new genomic data to the global context of COVID-19, particularly from the North African region, and highlights the importance of the timely molecular characterization of circulating strains. 相似文献
10.