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排序方式: 共有125条查询结果,搜索用时 968 毫秒
1.
Karaosmanoglu Ali Devrim Onur Mehmet Ruhi Salman Mehmet Coskun Usubutun Alp Karcaaltincaba Musturay Ozmen Mustafa Nasuh Akata Deniz 《Abdominal imaging》2019,44(4):1493-1505
Abdominal Radiology - Metastatic involvement of the ovaries is not rare. The most common tumor types metastasizing to the ovaries, from non-gynecological organs, are breast, colorectal, gastric,... 相似文献
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Nazir Ahmad Tahmina Ruhi 《Indian journal of otolaryngology and head and neck surgery》1994,46(2):96-100
BAEPS are coming up as an important investigatory tool in the hands of present clinicians and have a diagnostic and prognostic significance. The present study was carried on 25 patients. BAEPS were recorded at the time of admission and analysed. Absent BAEPS were associated with high mortality. Abnormal BAEPS were seen in infective and CVA group. Followup BAEPS showed no change in those patients who died. 相似文献
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Ali Devrim Karaosmano?lu Mehmet Ruhi Onur Ali Shirkhoda Mustafa Ozmen Peter F. Hahn 《Korean journal of radiology》2015,16(4):853-859
Malignant kidney neoplasms are the most frequently encountered solid kidney masses. Although renal cell carcinoma is the major renal malignancy, other solid malignant renal masses should be considered in the differential diagnosis of solid renal masses that do not contain a macroscopic fatty component. In this pictorial essay, we present the imaging findings of a primitive neuroectodermal tumor, primary liposarcoma of the kidney, primary neuroendocrine tumor, leiomyosarcoma, synovial sarcoma, malignant fibrous histiocytoma, sclerosing fibrosarcoma and renal metastasis of osteosarcoma. 相似文献
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TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children 总被引:7,自引:0,他引:7
Berdeli A Celik HA Ozyürek R Dogrusoz B Aydin HH 《Journal of molecular medicine (Berlin, Germany)》2005,83(7):535-541
The recently described family of toll-like receptors (TLRs) is a key player in host immunity by mediating inflammatory reactions against a wide range of pathogens. Mutations and polymorphisms in TLRs have revealed the importance of TLRs in human defence against diseases. TLR-2 is reported to interact with different bacterial structures, including lipoproteins, peptidoglycan and lipoteichoic acid. To assess the role of TLR-2 gene polymorphism in acute rheumatic fever (ARF) etiopathology, 61 independent Caucasian Turkish patients and 91 child and 116 adult controls were studied. Antistreptolycin O, C-reactive protein, sedimentation and white blood cell counts were studied to evaluate the clinical characteristics of the patients. Genomic DNA was extracted from peripheral blood using a standard column extraction technique. The Arg753Gln and Arg677Trp polymorphisms were genotyped by polymerase chain reaction (PCR) restriction fragment length polymorphism. The PCR products for the TLR-2 gene were analysed on 1.5% agarose gel pre-stained with ethidium bromide. Compared with healthy adult controls, the Arg753Arg genotype was significantly decreased in the entire group of ARF cases [odds ratio (OR) 0.01, 95% confidence interval (95% CI) 0.0034–0.031, p<0.0001]. Significantly, ARF patients were just 16 times more frequent with Gln allele (OR 15.6, 95% CI 7.87–30.8, p<0.0001). Moreover, evidence for an intensifying effect of the Gln allele was noteworthy when patients with Arg753Gln genotype were compared with healthy controls (OR 97.1, 95% CI 32.5–290, p<0.0001). However, no Arg677Trp polymorphism was detected in either patients or controls. Our data suggest that there is strong evidence for the biological role of TLR-2 in ARF. The common TLR-2 Arg to Gln polymorphism at position 753 significantly contributes to the pathogenesis of ARF. These results will allow the construction of a profile of individuals prone to ARF and may assist in developing new therapies. 相似文献
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OBJECTIVE: Angiotensin-converting enzyme inhibitors are an effective therapy for all stages of heart failure due to reduced systolic left ventricular function. Because sufficient data on intravenous angiotensin-converting enzyme inhibitors following coronary artery bypass surgery complicated by postoperative left ventricular dysfunction are unavailable, the efficacy and safety of intravenously administered enalaprilat were evaluated. DESIGN: A placebo-controlled, randomized, double-blind protocol. SETTING: Postoperative intensive care unit at the German Heart Institute Berlin. PATIENTS: Forty patients with a left ventricular ejection fraction <35% following coronary artery bypass surgery on the second postoperative day or after weaning from intra-aortic balloon counterpulsation. INTERVENTIONS: A loading dose of enalaprilat 0.625 mg infused over 1 hr was followed by 5 mg/24 hrs administered continuously for up to 72 hrs. MEASUREMENTS AND MAIN RESULTS: Systemic and pulmonary hemodynamic variables, blood gases, hormonal variables, renal function, and electrolytes were measured before and repeatedly during therapy. Acute effects were as follows: At 1 hr, enalaprilat increased the cardiac index (p <.001), stroke volume index (p <.001), and right ventricular stroke work index (p <.03) compared with placebo, whereas mean arterial pressure (p <.008) and both systemic (p <.001) and pulmonary (p <.02) vascular resistance decreased. Continuous effects were as follows: Over 72 hrs, enalaprilat decreased diastolic pulmonary artery pressure (p <.019), pulmonary artery occlusion pressure (p <.02), and central venous pressure (p <.02). The cardiac and stroke volume indexes were consistently higher in the enalaprilat group, whereas systemic and pulmonary vascular resistances were lower. The arterial blood-pressure lowering effect was blunted and heart rate remained unchanged. Mixed venous oxygenation (p <.02) was higher and arterial oxygenation was not modified. Finally, enalaprilat increased creatinine clearance (p <.002) and decreased creatinine (p <.02) and urea (p <.03). CONCLUSIONS: Intravenous enalaprilat safely and effectively improves cardiac and renal function following coronary artery bypass surgery complicated by postoperative left ventricular dysfunction. 相似文献
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Shear Wave Elastography Is a Reliable and Repeatable Method for Measuring the Elastic Modulus of the Rectus Femoris Muscle and Patellar Tendon
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Asthma is an important health problem in children. Substantial evidence has demonstrated that asthma is a chronic inflammatory disease with activation of the inflammatory cells within the airways. Recent studies have reported that systemic inflammation is related to disease progression in asthma.1 The pro-inflammatory cytokines such as tumour necrosis factor alpha (TNFα), interleukin 6 (IL-6) and C-reactive protein (CRP) are elevated in patients with asthma.1-3Atherosclerosis and asthma are both chronic inflammatory conditions. Inflammation leads to impairment of endothelial cell function, and chronic inflammation accelarates atherosclerosis.4 Elevated arterial stiffness, a marker of subclinical atherosclerosis, is associated with myocardial infarction, heart failure, stroke, renal disease and elevated total mortality rates.5Much research has revealed that patients with asthma are at increased risk of pulmonary embolism, hypertension, coronary heart disease and heart failure.6-9 Reduction in arterial distensibility leads to increased pulse pressure, and impedance of arterial flow and pulsatile cardiac work load. Arterial stiffness is a mechanical property related to vascular impedance and the afterload that is presented to the left ventricle. Abdominal aortic stiffness increases with age, and in many studies, its usefulness has been demonstrated.10-15In the literaure, changes in abdominal aortic stiffness in childhood-onset asthma have not been clearly determined. The purpose of our study was to evaluate abdominal aortic stiffness in patients with childhood-onset asthma. 相似文献
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