全文获取类型
收费全文 | 1200篇 |
免费 | 101篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 62篇 |
妇产科学 | 18篇 |
基础医学 | 123篇 |
口腔科学 | 58篇 |
临床医学 | 131篇 |
内科学 | 265篇 |
皮肤病学 | 42篇 |
神经病学 | 38篇 |
特种医学 | 230篇 |
外科学 | 93篇 |
综合类 | 103篇 |
预防医学 | 54篇 |
眼科学 | 11篇 |
药学 | 51篇 |
中国医学 | 6篇 |
肿瘤学 | 31篇 |
出版年
2023年 | 4篇 |
2022年 | 6篇 |
2021年 | 21篇 |
2020年 | 19篇 |
2019年 | 23篇 |
2018年 | 27篇 |
2017年 | 29篇 |
2016年 | 28篇 |
2015年 | 39篇 |
2014年 | 44篇 |
2013年 | 60篇 |
2012年 | 35篇 |
2011年 | 30篇 |
2010年 | 88篇 |
2009年 | 63篇 |
2008年 | 32篇 |
2007年 | 42篇 |
2006年 | 36篇 |
2005年 | 25篇 |
2004年 | 16篇 |
2003年 | 19篇 |
2002年 | 12篇 |
2001年 | 11篇 |
2000年 | 22篇 |
1999年 | 15篇 |
1998年 | 59篇 |
1997年 | 55篇 |
1996年 | 53篇 |
1995年 | 38篇 |
1994年 | 48篇 |
1993年 | 44篇 |
1992年 | 9篇 |
1991年 | 10篇 |
1990年 | 10篇 |
1989年 | 29篇 |
1988年 | 24篇 |
1987年 | 22篇 |
1986年 | 15篇 |
1985年 | 19篇 |
1984年 | 9篇 |
1983年 | 14篇 |
1982年 | 15篇 |
1981年 | 17篇 |
1980年 | 18篇 |
1979年 | 4篇 |
1978年 | 7篇 |
1977年 | 18篇 |
1976年 | 12篇 |
1975年 | 12篇 |
1956年 | 3篇 |
排序方式: 共有1322条查询结果,搜索用时 15 毫秒
1.
Needle-localized breast biopsy: why do we fail? 总被引:10,自引:0,他引:10
2.
J. Duteil FA Rambert AM Pointeau P. Mangiameli and E. Assous 《Fundamental & clinical pharmacology》1991,5(8):695-708
The potential antidepressant effect of flerobuterol (dl-(fluoro-2 phenyl)-1 t-butylamino-2 ethanol), a new drug related to beta-adrenoceptor agonists, was evaluated and compared with imipramine and salbutamol using classical psychopharmacological tests in mice. Like imipramine and salbutamol, flerobuterol (0.5-32 mg kg-1, ip) fully prevented apomorphine (16 mg kg-1, sc)- and partly reversed reserpine- and oxotremorine-induced hypothermia. At higher doses (16-32 mg kg-1), flerobuterol enhanced the toxic effects of yohimbine. Unlike imipramine, flerobuterol and salbutamol did not reduce immobility duration in the behavioural despair test. Salbutamol and flerobuterol decreased locomotor activity. Flerobuterol did not induce mydriasis, did not prevent oxotremorine-induced tremors or salivary and lacrimal gland secretion and did not reduce reserpine-induced palpebral ptosis. Propranolol (8 mg kg-1, ip) but not alpha-methyl-paratyrosine (75 mg kg-1, ip) prevented the flerobuterol-induced antagonism of apomorphine-induced hypothermia. Our results suggest that flerobuterol demonstrates potential antidepressant activity, which could be related to beta-adrenoceptor activation in mice. 相似文献
3.
Suppurative corneal ulceration in Bangladesh 总被引:8,自引:0,他引:8
AAS Dunlop MB BS ED Wright MRCPath † SA Howlader‡ I Nazrul‡ R Husain‡ K McClellan FRACO § FA Billson FRACO § 《Clinical & experimental ophthalmology》1994,22(2):105-110
Suppurative keratitis is an important preventable cause of blindness, particularly in the developing world. This study analyses 142 cases of suppurative keratitis referred to Chittagong Eye Infirmary, Bangladesh. Some 53.5% of cases were bacterial and 35.9% were fungal. The five most common pathogens were: Pseudomonas sp. 24%, Streptococcus pneumoniae 17%, Aspergillus sp. 13%, Fusarium sp. 7% and Curvularia sp. 6%. Gram stain and culture results were consistent in 62.6% of cases. Previous antibiotic treatment was a significant factor for failure of culture isolation and less so for Gram stain failure. On Gram stain, 55.9% of pseudomonal cases were missed, but only 2% of fungal cases were missed. Over all, Gram stain had a sensitivity of 62% and positive predictive value of 84% for bacterial cases, and 98% and 94% for fungal cases, respectively. Fungal ulcers were typically filamentous, but an antecedent history of trauma was not common. The most frequent injury was due to rice grains, but the inoculum appeared to be introduced during eye washing with contaminated water. Pseudomonal ulcers occurred most frequently in the monsoon season, and Fusarium cases were seen only in the hot, dry season. 相似文献
4.
5.
科室主任管理职能与基本素质探讨 总被引:11,自引:3,他引:8
人力资源在管理中发挥着重要作用,其中,科室主任作为医院人力资源的重要组成部分,在医院惯性运行和可持续发展中扮演着重要角色。因此,科室主任因其技术和管理双重职责所具备的管理职能、基本素质和领导艺术在日常工作中显得尤为关键。 相似文献
6.
GP SCHWAB AL BLUM E BODNER B DALLEMAGNE K GLASER H KOOP F PACE W RÖSCH JR SIEWERT G WETSCHER 《Journal of gastroenterology and hepatology》1997,12(12):785-789
Gastroesophageal reflux disease (GERD) is the most common disease of the upper gastrointestinal tract. With the introduction of proton pump inhibitors medical treatment of GERD has been significantly improved. However, the development of laparoscopic antireflux surgery resulted in an increasing interest of surgeons in this disease. An interactive meeting was organized in order to develop an agreement between gastoenterologists and surgeons regarding therapeutic decisions and this is the main topic of this paper. 相似文献
7.
8.
9.
10.
Edward?J?HolloxEmail author Jane?Davies Uta?Griesenbach Juliana?Burgess Eric?WFW?Alton John?AL?Armour 《Journal of negative results in biomedicine》2005,4(1):9
Human beta-defensin 2 (DEFB4, also known as DEFB2 or hBD-2) is a salt-sensitive antimicrobial protein that is expressed in
lung epithelia. Previous work has shown that it is encoded in a cluster of beta-defensin genes at 8p23.1, which varies in
copy number between 2 and 12 in different individuals. We determined the copy number of this locus in 355 patients with cystic
fibrosis (CF), and tested for correlation between beta-defensin cluster genomic copy number and lung disease associated with
CF. No significant association was found. 相似文献