全文获取类型
收费全文 | 1374篇 |
免费 | 91篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 75篇 |
妇产科学 | 15篇 |
基础医学 | 150篇 |
口腔科学 | 31篇 |
临床医学 | 139篇 |
内科学 | 271篇 |
皮肤病学 | 203篇 |
神经病学 | 39篇 |
特种医学 | 164篇 |
外科学 | 95篇 |
综合类 | 39篇 |
预防医学 | 75篇 |
眼科学 | 93篇 |
药学 | 50篇 |
中国医学 | 4篇 |
肿瘤学 | 30篇 |
出版年
2023年 | 5篇 |
2022年 | 4篇 |
2021年 | 17篇 |
2020年 | 23篇 |
2019年 | 24篇 |
2018年 | 19篇 |
2017年 | 27篇 |
2016年 | 25篇 |
2015年 | 29篇 |
2014年 | 32篇 |
2013年 | 45篇 |
2012年 | 35篇 |
2011年 | 35篇 |
2010年 | 53篇 |
2009年 | 47篇 |
2008年 | 36篇 |
2007年 | 46篇 |
2006年 | 37篇 |
2005年 | 43篇 |
2004年 | 33篇 |
2003年 | 37篇 |
2002年 | 35篇 |
2001年 | 28篇 |
2000年 | 50篇 |
1999年 | 39篇 |
1998年 | 54篇 |
1997年 | 49篇 |
1996年 | 38篇 |
1995年 | 26篇 |
1994年 | 41篇 |
1993年 | 35篇 |
1992年 | 30篇 |
1991年 | 44篇 |
1990年 | 37篇 |
1989年 | 36篇 |
1988年 | 32篇 |
1987年 | 39篇 |
1986年 | 24篇 |
1985年 | 29篇 |
1984年 | 20篇 |
1983年 | 25篇 |
1982年 | 15篇 |
1981年 | 11篇 |
1980年 | 16篇 |
1979年 | 10篇 |
1978年 | 7篇 |
1977年 | 14篇 |
1976年 | 9篇 |
1975年 | 8篇 |
1971年 | 4篇 |
排序方式: 共有1480条查询结果,搜索用时 31 毫秒
1.
The incidence of eye infections in a community is generally accepted as an indicator of the adequacy of water supply for their needs. However, discrepancies in the published results from various studies seem to challenge this view. We have reanalysed the published data on trachoma in relation to the most relevant indicators of water accessibility, using prevalence ratios as the single parameter for risk assessment. A definite trend emerges from this review: the incidence of infectious conjunctivitis is not sensitive to differences in water accessibility; on the other hand, a reduction in the risk of trachoma is consistently associated with better access to water. This conclusion may support the efforts of WHO and other multilateral and bilateral agencies to sustain the commitment towards the water supply sector beyond the International Drinking Water Supply and Sanitation Decade. 相似文献
2.
3.
The effect of chemical shift on magnetic resonance (MR) imaging of the pituitary fossa was studied. Healthy volunteers underwent conventional MR imaging of the pituitary fossa and then imaging with the frequency-encoding gradient reversed or with the phase- and frequency-encoding gradients interchanged. Comparison of the image pairs in each subject showed that the thin, black stripe evident at the water-fat interface within the pituitary fossa was altered when the gradients were changed. Therefore, the low-intensity signal within the pituitary fossa is a chemical shift misregistration effect. 相似文献
4.
GP SCHWAB AL BLUM E BODNER B DALLEMAGNE K GLASER H KOOP F PACE W RÖSCH JR SIEWERT G WETSCHER 《Journal of gastroenterology and hepatology》1997,12(12):785-789
Gastroesophageal reflux disease (GERD) is the most common disease of the upper gastrointestinal tract. With the introduction of proton pump inhibitors medical treatment of GERD has been significantly improved. However, the development of laparoscopic antireflux surgery resulted in an increasing interest of surgeons in this disease. An interactive meeting was organized in order to develop an agreement between gastoenterologists and surgeons regarding therapeutic decisions and this is the main topic of this paper. 相似文献
5.
6.
M. Prost 《The British journal of ophthalmology》1988,72(5):363-367
The angiogenic activity of various parts of the retina in kittens with oxygen-induced retinopathy has been studied by the use of a corneal micropocket technique and chorioallantoic assay. The results indicate that in retinopathy of prematurity the most important role in the pathogenesis of fibrovascular proliferation is played by the so-called primary avascular retina, that is, that part of the retina which has not yet been vascularised during ontogenesis. 相似文献
7.
8.
P Bernard C Prost N Durepaire N Basset-Seguin L Didierjean J H Saurat 《The Journal of investigative dermatology》1992,99(2):174-179
Recent studies have shown that sera from patients with cicatricial pemphigoid (CP) contained autoantibodies against epidermal antigens of molecular weight 230 kD and/or 180 kD by immunoblotting, similar to those recognized by bullous pemphigoid (BP) sera. Previous immunoprecipitation studies have shown that BP sera only precipitated the 230-kD antigen. To characterize the CP antigen(s) we tested 10 CP sera, 10 BP sera, and four controls by both immunoprecipitation of radiolabeled cells and immunoblotting of epidermal extracts. For immunoprecipitation, we used 0.5% NP-40 extracts of both normal human keratinocytes and Pam cells. All CP sera precipitated a 180-kD protein that co-migrated with the BP180 antigen precipitated by some individual BP sera. Two of these CP sera also faintly bound a 230-kD protein of similar molecular weight as the major BP230 antigen. CP and BP sera with an immunoblotting pattern of 180 kD immunoprecipitated a co-migrating 180-kD protein. CP sera reacting by immunoblotting with the 230-kD antigen precipitated the 180-kD and/or the 230-kD antigen. In contrast, BP sera reacting with the 230-kD antigen only precipitated this antigen. In further experiments, labeled 0.5% NP-40 extracts from Pam cells were first preabsorbed with a reference BP serum and then immunoprecipitated with CP sera. Under these conditions, CP sera that immunoprecipitated both 180-kD and 230-kD proteins with the standard procedure no longer precipitated these proteins. Our results suggest that a 180-kD protein is the major CP target-antigen that demonstrated immunologic cross-reactivities with the BP180 and the BP230 antigens. 相似文献
9.
10.
Edward?J?HolloxEmail author Jane?Davies Uta?Griesenbach Juliana?Burgess Eric?WFW?Alton John?AL?Armour 《Journal of negative results in biomedicine》2005,4(1):9
Human beta-defensin 2 (DEFB4, also known as DEFB2 or hBD-2) is a salt-sensitive antimicrobial protein that is expressed in
lung epithelia. Previous work has shown that it is encoded in a cluster of beta-defensin genes at 8p23.1, which varies in
copy number between 2 and 12 in different individuals. We determined the copy number of this locus in 355 patients with cystic
fibrosis (CF), and tested for correlation between beta-defensin cluster genomic copy number and lung disease associated with
CF. No significant association was found. 相似文献