全文获取类型
收费全文 | 1918篇 |
免费 | 103篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 77篇 |
妇产科学 | 35篇 |
基础医学 | 218篇 |
口腔科学 | 47篇 |
临床医学 | 141篇 |
内科学 | 363篇 |
皮肤病学 | 25篇 |
神经病学 | 271篇 |
特种医学 | 455篇 |
外科学 | 174篇 |
综合类 | 43篇 |
预防医学 | 33篇 |
眼科学 | 8篇 |
药学 | 52篇 |
1篇 | |
肿瘤学 | 66篇 |
出版年
2023年 | 8篇 |
2022年 | 8篇 |
2021年 | 19篇 |
2020年 | 12篇 |
2019年 | 16篇 |
2018年 | 28篇 |
2017年 | 27篇 |
2016年 | 23篇 |
2015年 | 32篇 |
2014年 | 45篇 |
2013年 | 75篇 |
2012年 | 54篇 |
2011年 | 70篇 |
2010年 | 67篇 |
2009年 | 72篇 |
2008年 | 56篇 |
2007年 | 71篇 |
2006年 | 58篇 |
2005年 | 47篇 |
2004年 | 43篇 |
2003年 | 32篇 |
2002年 | 31篇 |
2001年 | 32篇 |
2000年 | 30篇 |
1999年 | 33篇 |
1998年 | 87篇 |
1997年 | 86篇 |
1996年 | 85篇 |
1995年 | 65篇 |
1994年 | 41篇 |
1993年 | 59篇 |
1992年 | 18篇 |
1991年 | 21篇 |
1990年 | 34篇 |
1989年 | 55篇 |
1988年 | 46篇 |
1987年 | 49篇 |
1986年 | 57篇 |
1985年 | 67篇 |
1984年 | 35篇 |
1983年 | 32篇 |
1982年 | 28篇 |
1981年 | 31篇 |
1980年 | 39篇 |
1979年 | 5篇 |
1978年 | 18篇 |
1977年 | 23篇 |
1976年 | 22篇 |
1975年 | 21篇 |
1963年 | 2篇 |
排序方式: 共有2025条查询结果,搜索用时 15 毫秒
1.
Isolated patellofemoral arthritis is an increasingly recognized entity, and is usually associated with previous patellofemoral dysplasia or instability. Patellofemoral arthroplasty (PFA) has evolved significantly in recent years, both in terms of implant design and importantly in the understanding of appropriate patient selection. This review outlines the indications and investigations for PFA, provides a brief history of the development of contemporary implants, and presents the clinical outcomes for the prostheses most commonly used in the UK. In addition, it provides a detailed surgical technique for implantation of an onlay implant, with tips on how to optimize patellofemoral biomechanics and thus achieve a consistently good outcome. 相似文献
2.
Here we report how the different types of regional muscle involvement, i.e. bulbar, ocular or generalized, in patients with myasthenia gravis (MG) influence the mental aspects of quality of life. Clinical examination according to Osserman was performed in 48 MG patients (45 women, three men; mean age 54, SD 12 years). Each patient was at the time for clinical evaluation asked to fill out the disease-specific Myasthenia Gravis Questionnaire (MGQ) and the Short-Form 36-item questionnaire for health survey (SF-36) as patient-oriented tools. We related the regional domains (generalized domain, bulbar domain and ocular domain) of the MGQ and the clinical findings, respectively, with mental quality of life as assessed by SF-36. Bulbar and generalized involvement results in impairment of mental aspects of quality of life, whereas ocular involvement does not. 相似文献
3.
Early micromotion of implant components and periprosthetic bone loss in patients undergoing total knee arthroplasty are thought
to contribute to late aseptic loosening. In the pursuit of longer implant survival, the administration of bisphosphonates
may be advocated as a means to buffer implants against microinstability and periprosthetic bone loss. A bibliographic search
identified one metaanalysis and two randomised controlled trials dealing with this topic. Current evidence supports the hypothesis
that the inhibiting effects of bisphosphonates on bone resorption reduce implant micromotion and periprosthetic bone loss
at the one-year follow-up. Tested bisphosphonates include clodronate, pamidronate and alendronate. However, a decline in periprosthetic
BMD is observed at the three-year follow-up following a sixmonth course of bisphosphonate administration. Length of follow-up
in available studies is currently too short to determine whether bisphosphonates increase the longevity of implants. Furthermore,
the optimal dose, modality and length of bisphosphonate administration have yet to be determined. 相似文献
4.
D. Caroline Blanchard Jon K. Shepherd Antonio De Padua Carobrez Robert J. Blanchard 《Neuroscience and biobehavioral reviews》1991,15(4):461-468
Female rats consistently show a pattern of differences in defensive behaviors compared to males which parallel the effects of exposure to a nonpainful threat stimulus (cat or cat odor) in the same tests and measures. These indications of greater defensiveness for females are particularly common in situations involving potential, as opposed to actual and present, threat, a factor which probably also reflects ceiling or floor effects in situations involving very intense defensiveness. In addition, pharmacological studies indicate sex differences in the effects of selective serotonin (5-HT) receptor agonists and antagonists on defensive responding. These findings indicate that sex effects must be considered in studies of the pharmacological control of defensive behaviors, and suggest that responsivity to sex effects may be an additional criterion for the suitability of animal models of anxiety. 相似文献
5.
RA O. Hempel 《Notfall & Rettungsmedizin》2007,10(5):367-371
Legal uncertainties for emergency vehicle drivers can be avoided when fundamental rules are established. In particular, differentiation of special rights and rights of way is essential. Inherent in both is the urgency necessary to save human lives. The right of way signaled by flashing blue lights and siren does not however justify traffic violations but signifies rather a request to other traffic participants. In contrast, special rights require no announcement and constitute a justifiable reason for traffic violations. Even so they do not allow that other traffic participants be endangered or harmed. Adherence to these basic principles can prevent legal misinterpretations as well as rigid adoption of inflexible standards of behavior. 相似文献
6.
RA Mag. Dr. C. Gepart 《Notfall & Rettungsmedizin》2007,10(4):289-292
Austria’s new Living Wills Act (Patientenverfügungsgesetz, or PatVG) that came into effect on 1st of June 2006, is the first law in Austria to regulate the controversial issue of living wills. The PatVG provides for a right to refuse future medical treatment by making an advance directive in the form of a living will that is either binding or “to be taken into consideration”. However, the establishment of a binding living will is governed by strict criteria as regards form and content, and both a medical doctor and a legal expert must be involved. Compliance with a living will is not allowed where there is a legal obligation to give medical treatment. There is also a legal obligation to give medical treatment in emergency situations where the time involved in looking for a living will could seriously endanger the health or the life of a patient. 相似文献
7.
R. Bondì R. Padua L. Bondì A. Battaglia E. Romanini A. Campi 《Journal of orthopaedics and traumatology》2007,8(1):36-41
Abstract Calcaneal fracture is the most common of the tarsal fractures and represents 1%–2% of all fractures. The fractures may be
divided into extra-articular (not affecting the joint) and intra-articular (involving the talo-calcaneal and calcaneal cuboid
joints) types. The management of heel fractures includes nonoperative and operative treatments, but no clear consensus has
been reached. The choice of operative treatment is still controversial with many factors influencing the final clinical outcome.
Many studies have assessed the outcome of treatment of calcaneal fractures, but there is a general disagreement on their management.
The objective of this study was to collect and evaluate the scientific evidence reported in the literature supporting the
different treatments for calcaneal fractures. 相似文献
8.
Ohne Zusammenfassung 相似文献
9.
Both cyproterone acetate (CPA) and the gonadotrophin-releasing hormone
agonist (GnRHa) have been shown to be effective for the treatment of
hirsutism. We wished to compare the effectiveness of CPA in two standard
doses with GnRHa and add-back therapy and to compare the length of
remission after these treatments. A total of 60 hirsute hyperandrogenic
women was assigned to the following treatment groups: CPA 2 mg with 35
microg of ethinylestradiol for 21 days each month (Diane group), CPA 50 mg,
days 5-15, and ethinylestradiol 50 microg, days 5-25, each month (CPA
group) or Decapeptyl 3.75 mg i.m. every 28 days with the addition of
conjugated oestrogen 0.625 mg, days 1-21, and medroxyprogesterone acetate
10 mg, days 12-21 (GnRHa group). Hirsutism was graded by the
Ferriman-Gallwey-Lorenzo (FGL) index and anagen hair shaft diameters and
serum luteinizing hormone (LH) and testosterone were assessed before and
every 3 months during and after treatment. All women were treated for 1
year with 1 year follow-up. At baseline hirsutism and endocrine patterns
were similar in all groups. After one year of treatment, hirsutism
decreased in all groups but the changes were greater (P <0.05) in the
CPA and GnRHa groups than in the Diane group. Serum LH and testosterone
were lowest in the GnRHa group. After withdrawal, hirsutism increased
rapidly in the Diane and CPA groups and after 6 months, FGL scores and hair
shaft diameters were similar to pretreatment values. In the GnRHa group,
hirsutism increased more gradually and after 1 year of withdrawal, FGL
scores and hair diameters were significantly (P <0.05) less than
pretreatment values. Serum LH and testosterone increased rapidly in all
three groups reaching pretreatment values by 6 months. These data suggest
equal efficacy of the GnRHa and the high dose CPA regimen for the treatment
of hirsutism in hyperandrogenic women. GnRHa with add-back treatment
appears to result in a longer remission of hirsutism in comparison with
CPA.
相似文献
10.