全文获取类型
收费全文 | 3390篇 |
免费 | 228篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 62篇 |
儿科学 | 129篇 |
妇产科学 | 37篇 |
基础医学 | 498篇 |
口腔科学 | 64篇 |
临床医学 | 320篇 |
内科学 | 664篇 |
皮肤病学 | 100篇 |
神经病学 | 274篇 |
特种医学 | 70篇 |
外科学 | 611篇 |
综合类 | 18篇 |
一般理论 | 31篇 |
预防医学 | 296篇 |
眼科学 | 32篇 |
药学 | 149篇 |
中国医学 | 2篇 |
肿瘤学 | 270篇 |
出版年
2022年 | 20篇 |
2021年 | 37篇 |
2020年 | 33篇 |
2019年 | 38篇 |
2018年 | 64篇 |
2017年 | 54篇 |
2016年 | 65篇 |
2015年 | 71篇 |
2014年 | 78篇 |
2013年 | 125篇 |
2012年 | 162篇 |
2011年 | 152篇 |
2010年 | 105篇 |
2009年 | 100篇 |
2008年 | 172篇 |
2007年 | 172篇 |
2006年 | 168篇 |
2005年 | 167篇 |
2004年 | 152篇 |
2003年 | 151篇 |
2002年 | 146篇 |
2001年 | 66篇 |
2000年 | 55篇 |
1999年 | 73篇 |
1998年 | 52篇 |
1997年 | 49篇 |
1996年 | 47篇 |
1995年 | 49篇 |
1994年 | 32篇 |
1993年 | 30篇 |
1992年 | 50篇 |
1991年 | 62篇 |
1990年 | 49篇 |
1989年 | 50篇 |
1988年 | 59篇 |
1987年 | 40篇 |
1986年 | 41篇 |
1985年 | 35篇 |
1984年 | 34篇 |
1983年 | 45篇 |
1982年 | 34篇 |
1981年 | 33篇 |
1979年 | 33篇 |
1978年 | 23篇 |
1977年 | 22篇 |
1976年 | 27篇 |
1974年 | 22篇 |
1971年 | 21篇 |
1970年 | 21篇 |
1967年 | 23篇 |
排序方式: 共有3627条查询结果,搜索用时 15 毫秒
1.
Michael W. Manning Yi-Ju Li Dean Linder John C. Haney Yi-Hung Wu Mihai V. Podgoreanu Madhav Swaminathan Jacob N. Schroder Carmelo A. Milano Ian J. Welsby Mark Stafford-Smith Kamrouz Ghadimi 《Journal of cardiothoracic and vascular anesthesia》2021,35(5):1310-1318
- Download : Download high-res image (215KB)
- Download : Download full-size image
2.
L. Misery E. Weisshaar E. Brenaut A.W.M. Evers F. Huet S. Ständer A. Reich E. Berardesca E. Serra-Baldrich J. Wallengren D. Linder J.W. Fluhr J.C. Szepietowski H. Maibach for the Special Interest Group on sensitive skin of the International Forum for the Study of Itch 《Journal of the European Academy of Dermatology and Venereology》2020,34(2):222-229
The special interest group on sensitive skin of the International Forum for the Study of Itch previously defined sensitive skin as a syndrome defined by the occurrence of unpleasant sensations (stinging, burning, pain, pruritus and tingling sensations) in response to stimuli that normally should not provoke such sensations. This additional paper focuses on the pathophysiology and the management of sensitive skin. Sensitive skin is not an immunological disorder but is related to alterations of the skin nervous system. Skin barrier abnormalities are frequently associated, but there is no cause and direct relationship. Further studies are needed to better understand the pathophysiology of sensitive skin – as well as the inducing factors. Avoidance of possible triggering factors and the use of well-tolerated cosmetics, especially those containing inhibitors of unpleasant sensations, might be suggested for patients with sensitive skin. The role of psychosocial factors, such as stress or negative expectations, might be relevant for subgroups of patients. To date, there is no clinical trial supporting the use of topical or systemic drugs in sensitive skin. The published data are not sufficient to reach a consensus on sensitive skin management. In general, patients with sensitive skin require a personalized approach, taking into account various biomedical, neural and psychosocial factors affecting sensitive skin. 相似文献
3.
4.
5.
Olle Zetterström Christer Andersson Leif Eriksson ers Fredriksson Johan Friskopp Gunnar Heden Bernt Jansson Tord Lundgren Rolf Nilveus ers Olsson Stefan Renvert Lars Salonen Lars Sjöström ers Winell ers Östgren Stina Gestrelius 《Journal of clinical periodontology》1997,24(9):697-704
Abstract The aim of the present clinical trial was to test tolerability during 2 treatments with EMDOGAIN® in a large number of patients. An open, controlled study design in 10 Swedish specialist clinics was chosen, with a test group of 107 patients treated with EMDOGAIN® in connection with periodontal surgery at 2 surgical test sites per patient. The procedures were performed 2 to 6 weeks apart on one-rooted teeth with at least 4 mm deep intraosseous lesions. A control group of 33 patients underwent flap surgery without EMDOGAIN® at I comparable site. In total 214 test and 33 control surgeries were performed. Serum samples were obtained from test patients for analysis of total and specific antibody levels. 10 of the patients had samples taken before and after the first surgery. 56 other samples were taken after one treatment with EMDOGAIN®, and 63 after 2 treatments. None of the samples, not even from allergy-prone patients after 2 treatments, indicated deviations from established baseline ranges. This indicates that the immunogenic potential of EMDOGAIN® is extremely low when applied in conjunction with periodontal surgery. Comparison between the test and control groups demonstrated the same type and frequency of post-surgical experiences, i.e., reactions caused by the surgical procedure itself. Clinical probing and radiographic evaluation was performed at baseline and 8 months postsurgery. About half of the patients (44 test and 21 control) were also evaluated after 3 years. There was a significant difference between the test and control results at 8 months post surgery. and this difference had increased further at the 3 year follow-up. The 2.5–3 mm increase in attachment and bone level after treatment with EMDOGAIN® was of the same magnitude as seen in the studies with split-mouth design aiming for lest of effectiveness of EMDOGAIN®. 相似文献
6.
7.
8.
9.
Per H. Morberg Olle G. P. Isaksson Carina B. Johansson Jonas Sandstedt Jan F. T rnell 《Acta orthopaedica》1997,68(4):344-348
Several recent studies have investigated the effects of growth hormone (GH) on the healing of fractures and bone ingrowth, but with conflicting results. The negative results may be due to antibody formation against injected GH or because some experimental models are able to prove only positive GH effects. In this study, we wanted to investigate the effect of GH on implant integration in bone. To avoid potential formation of antibodies against injected GH, we used a model with transgenic mice overexpressing bovine GH (bGH).
Titanium implants were inserted in the forehead of the mice. 4 months after insertion, the implants were cut out en bloc with the surrounding bone. The calcified specimens were cut and ground to a thickness of approximately 10m. Histomorphometry demonstrated significantly more direct bone-to-metal contact in the transgenic mice than in the nontransgenic littermates. Our findings indicate that systemic administration of GH in humans may improve implant integration in bone. 相似文献
Titanium implants were inserted in the forehead of the mice. 4 months after insertion, the implants were cut out en bloc with the surrounding bone. The calcified specimens were cut and ground to a thickness of approximately 10m. Histomorphometry demonstrated significantly more direct bone-to-metal contact in the transgenic mice than in the nontransgenic littermates. Our findings indicate that systemic administration of GH in humans may improve implant integration in bone. 相似文献
10.
Gsta Berlin Aril Frydn Rolf Maller Claes Malm Olle Vikrot 《European journal of haematology》1981,25(2):171-174
At our hospital 15 cases of leukaemic reticuloendotheliosis and 4 cases of Legionnaires' disease have been diagnosed. 3 patients had both diseases. The clinical findings are reported. It is probable that patients with leukaemic reticuloendotheliosis have an increased susceptibility to Legionnaires' disease. Possible reasons for the decreased resistance are discussed. 相似文献