全文获取类型
收费全文 | 2403篇 |
免费 | 91篇 |
国内免费 | 27篇 |
专业分类
耳鼻咽喉 | 56篇 |
儿科学 | 142篇 |
妇产科学 | 101篇 |
基础医学 | 201篇 |
口腔科学 | 84篇 |
临床医学 | 183篇 |
内科学 | 469篇 |
皮肤病学 | 46篇 |
神经病学 | 178篇 |
特种医学 | 128篇 |
外科学 | 581篇 |
综合类 | 22篇 |
预防医学 | 55篇 |
眼科学 | 98篇 |
药学 | 91篇 |
肿瘤学 | 86篇 |
出版年
2024年 | 1篇 |
2023年 | 20篇 |
2022年 | 27篇 |
2021年 | 63篇 |
2020年 | 35篇 |
2019年 | 45篇 |
2018年 | 64篇 |
2017年 | 44篇 |
2016年 | 86篇 |
2015年 | 89篇 |
2014年 | 95篇 |
2013年 | 146篇 |
2012年 | 182篇 |
2011年 | 182篇 |
2010年 | 104篇 |
2009年 | 86篇 |
2008年 | 194篇 |
2007年 | 220篇 |
2006年 | 188篇 |
2005年 | 186篇 |
2004年 | 144篇 |
2003年 | 93篇 |
2002年 | 75篇 |
2001年 | 32篇 |
2000年 | 24篇 |
1999年 | 22篇 |
1998年 | 13篇 |
1997年 | 9篇 |
1996年 | 5篇 |
1995年 | 3篇 |
1994年 | 5篇 |
1993年 | 3篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1989年 | 6篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1985年 | 10篇 |
1983年 | 2篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1973年 | 2篇 |
1970年 | 1篇 |
1966年 | 2篇 |
排序方式: 共有2521条查询结果,搜索用时 31 毫秒
1.
2.
Mehmet Oguz Yenidunya Mustafa Erol Demirseren Serdar Gorkem Bulent Adil Tasbas Candemir Ceran 《European journal of plastic surgery》2007,29(7):327-330
Nonunion in the forearm following a radioulnar fracture is one of the nightmares of the orthopedic surgeon. Fortunately, it
is rare. We treated a large bone defect of the forearm, using a vascularized fibular graft after excision of the unhealed
bone segment in a 10-year-old boy with neurofibromatosis. This situation followed a double fracture that had been operated
on several times using conventional methods. Following the debridement of the unhealthy tissues in the pseudoarthrotic region,
the vascularized fibula was placed on the dorsal surface of the proximal radius fragment. The distal fragment of the radius
was inserted into the fibular cavity and fixation was established with a Kirschner wire distally and with a plate proximally.
Only two screws were used to fix the plate. The peroneal artery was anastomosed with the radial artery; one of its venae comitantes
was anastomosed with the cephalic vein in an end-to-end fashion. After surgery, the elbow was immobilized at 90 degrees of
flexion with a splint for 6 weeks. One year after surgery, forearm stabilization and elbow and hand functions were very satisfactory.
However, because the distal epiphyses of the bones were destroyed following the repeated surgery and the original trauma itself,
a very prominent difference between the two forearms occurred, suggesting the need for bone lengthening in the future. By
presenting this case we would like to conclude that one can expect good bone healing with a vascularized bone transfer in
these cases when there is not enough space to place screws, but support can be provided by an external splint and K wire. 相似文献
3.
OBJECTIVE: The study goal was to evaluate whether quantitative analysis of neck drainage contents is an important parameter of objective and early diagnosis of chylous fistula (CF) in the postoperative period. STUDY DESIGN AND SETTING: We prospectively evaluated 103 consecutive neck dissections during a 2-year period at a tertiary academic referral center. Six of the patients (5.8%) had CF. The data obtained from the patients with CF were matched with normal data obtained from patients without CF. RESULTS: A statistically significant difference was found between total drainage volumes of the patients with and those without CF (P < 0.05). In almost all patients with CF, drainage levels of triglycerides and cholesterol on postoperative day 1 were higher than serum levels. The difference between the drainage levels of triglycerides and cholesterol of the patients with and without CF was highly significant (P < 0.001). CONCLUSIONS: Serum and drainage levels of triglycerides and cholesterol on postoperative day 1 can be used as objective and early predictive parameters of CF. 相似文献
4.
Background
The combination therapies recommended by the World Health Organization for treatment of brucellosis are doxycycline plus rifampicin or doxycycline plus streptomycin. Although highly successful results have been obtained with these two regimens, relapse rates as high as 14.4%. The most effective and the least toxic chemotherapy for human brucellosis is still undetermined. The aim of the present study was to investigate the efficacy, adverse effects and cost of ofloxacin plus rifampicin therapy, and doxycycline plus rifampicin therapy and evaluate in the treatment of brucellosis. 相似文献5.
In this prospective study done between 1983 and 1989, of 109 children with acute renal failure in Sivas, Turkey, infectious disease was found in 94. This was related mainly to preventable disease such as acute gastro-enteritis, sepsis and post-streptococcal acute glomerulonephritis. Within this infectious disease group, the highest incidence rate was found in sepsis. 相似文献
6.
Polyester-crystic cast was observed to reach the peritubular capillary plexus following injection in sheep kidneys. Microvascular structures in this region are also reported in this study. Glomeruli were found to vary in size and shape. Diameters of afferent arterioles were larger than those of efferent arterioles. The glomerulus is supplied by more than one afferent arteriole, and in some regions, the blood in afferent arterioles joins collateral circulation via the intercapillary plexus. Morphological properties at the end of the peritubular capillary plexus were found to be remarkably significant. 相似文献
7.
8.
Sevcan A Bakkaloglu Necla Buyan Tohru Funahashi Hatice Pasaoglu Atilla H Elhan Enver Hasanoglu Oguz Soylemezoglu 《Peritoneal dialysis international》2005,25(4):357-361
BACKGROUND: Atherosclerotic vascular diseases are the major cause of mortality in patients with end-stage renal disease (ESRD) treated with chronic peritoneal dialysis (CPD), even in children. Adiponectin (ADPN) is a recently discovered adipocyte-derived plasma protein having anti-atherogenic properties. ADPN levels are elevated in ESRD but it has been reported that ESRD patients with low plasma ADPN levels have a high risk of cardiovascular death. OBJECTIVE: To clarify the atherosclerotic risk and especially the significance of ADPN levels in pediatric patients on CPD. DESIGN: Cross-sectional studyin the pediatric peritoneal dialysis unit of a university hospital. PATIENTS: 18 children, aged 12.6 +/- 5.6 years, being treated with CPD and 20 healthy age- and sex-matched control subjects were enrolled in this study. METHODS: Serum ADPN levels and other risk factors, including blood pressure, blood glucose, serum lipid/lipoprotein fractions, apolipoprotein B, C-reactive protein (CRP), lipoprotein(a), and homocysteine levels, were studied in CPD patients and compared to the controls. RESULTS: Serum ADPN levels were three times higher in the CPD group compared to the control subjects, as was previously reported. Apolipoprotein B and CRP levels were also high in the CPD group. No significant difference was found in other atherosclerotic parameters, including lipoprotein(a) and homocysteine levels. Interestingly, we found a negative correlation between log ADPN and creatinine levels among the CPD patients (r = -0.54, p < 0.05). There was no correlation between log ADPN and duration of CPD. Creatinine and low-density lipoprotein levels could account for 54% of the total variation in ADPN levels. CONCLUSION: Among pediatric CPD patients, serum levels of the anti-atherogenic protein, ADPN, were inversely associated with creatinine. ADPN level might be a novel marker to predict prognosis in pediatric CPD patients. 相似文献
9.
Gursel Dursun Ozan Bagis Ozgursoy Ozgur Kemal Isil Coruh 《European archives of oto-rhino-laryngology》2007,264(9):1027-1032
The purpose of this study was to present our experience with combined use of CO2 laser and cold instrumentation for Reinke’s edema surgery and to evaluate 1-year follow-up results of the technique in a
series of professional voice users. Fifteen patients with Reinke’s edema who underwent microlaryngoscopic surgery were included.
Videolaryngostroboscopy, perceptual and acoustic voice analyses were performed before and after surgery. During the 1-year
follow-up, no recurrence of Reinke’s edema was encountered. Significant postoperative improvement was obtained in the quality
of voice, in terms of GRBAS scores, Fo, jitter, shimmer and NHR. No evidence of laryngeal cancer was found on the histological
examinations. Combined use of CO2 laser and cold instrumentation provides a reliable and safe method for Reinke’s edema surgery, and cessation of smoking,
voice rest and control of the laryngopharyngeal reflux contribute to the success of surgery. We consider that the removal
of redundant mucosa of the vocal fold reduces the risk of the recurrence of Reinke’s edema and provides better quality of
voice. However, it does not imply that our method is superior to others’, but this procedure constitutes an effective treatment
of choice for Reinke’s edema patients, including professional voice users. 相似文献
10.
A 2-year-old boy with known sickle cell disease presented in acute coma. CT revealed bilateral thalamic infarcts and incomplete sinus thrombosis. Angiography confirmed thrombosis of the straight sinus and vein of Galen. 相似文献