全文获取类型
收费全文 | 1989篇 |
免费 | 134篇 |
国内免费 | 66篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 145篇 |
妇产科学 | 44篇 |
基础医学 | 268篇 |
口腔科学 | 86篇 |
临床医学 | 241篇 |
内科学 | 451篇 |
皮肤病学 | 38篇 |
神经病学 | 122篇 |
特种医学 | 262篇 |
外科学 | 131篇 |
综合类 | 53篇 |
预防医学 | 134篇 |
眼科学 | 38篇 |
药学 | 111篇 |
肿瘤学 | 58篇 |
出版年
2021年 | 16篇 |
2020年 | 9篇 |
2019年 | 13篇 |
2018年 | 11篇 |
2017年 | 19篇 |
2016年 | 23篇 |
2015年 | 31篇 |
2014年 | 32篇 |
2013年 | 46篇 |
2012年 | 84篇 |
2011年 | 81篇 |
2010年 | 56篇 |
2009年 | 66篇 |
2008年 | 78篇 |
2007年 | 128篇 |
2006年 | 81篇 |
2005年 | 74篇 |
2004年 | 58篇 |
2003年 | 60篇 |
2002年 | 70篇 |
2001年 | 54篇 |
2000年 | 59篇 |
1999年 | 44篇 |
1998年 | 77篇 |
1997年 | 81篇 |
1996年 | 81篇 |
1995年 | 69篇 |
1994年 | 48篇 |
1993年 | 57篇 |
1992年 | 28篇 |
1991年 | 37篇 |
1990年 | 30篇 |
1989年 | 61篇 |
1988年 | 45篇 |
1987年 | 55篇 |
1986年 | 33篇 |
1985年 | 41篇 |
1984年 | 28篇 |
1983年 | 38篇 |
1982年 | 23篇 |
1981年 | 20篇 |
1980年 | 24篇 |
1979年 | 11篇 |
1977年 | 12篇 |
1975年 | 12篇 |
1971年 | 8篇 |
1970年 | 10篇 |
1969年 | 10篇 |
1967年 | 8篇 |
1966年 | 8篇 |
排序方式: 共有2189条查询结果,搜索用时 15 毫秒
1.
OBJECTIVE: To assess the frequency of risk factors for rhabdomyolysis with simvastatin and atorvastatin in cases reported to the Australian Adverse Drug Reactions Advisory Committee (ADRAC). DESIGN: Reports meeting the definition of rhabdomyolysis were reviewed for risk factors including age > or = 70 years, dose > or = 40 mg, hepatic dysfunction, diabetes mellitus, hyperkalaemia, hypothyroidism and the use of concomitant interacting medications. RESULTS: Only one report associated with simvastatin and five reports associated with atorvastatin did not list any risk factors for rhabdomyolysis. Interacting medicines featured in 77% of reports of rhabdomyolysis associated with simvastatin and 44% of reports associated with atorvastatin. A comparison of the age profile for reports of atorvastatin- and simvastatin-associated rhabdomyolysis with that for all adverse drug reaction reports received, and for all reports of muscle disorders, suggested a trend towards an increasing risk of rhabdomyolysis with increasing age with simvastatin but not with atorvastatin. Similarly, comparing prescribed tablet strengths from Pharmaceutical Benefits Scheme data with the HMG-CoA reductase inhibitor ('statin') doses in reports of rhabdomyolysis suggested a dose-related risk with simvastatin, but a less increased risk with high-dose atorvastatin. CONCLUSION: Risk factors for rhabdomyolysis featured in nearly all of the reports of statin-associated rhabdomyolysis and the majority of reports listed multiple risk factors, although dependence on risk factors appeared to be stronger with simvastatin than atorvastatin. The multiplication of risk factors in patients taking simvastatin and atorvastatin should be minimised. 相似文献
2.
To determine whether well-appearing children found incidentally to be neutropenic are at risk for an infectious complication, 44 consecutive months of hematology laboratory records were reviewed. One hundred nineteen patients had medical record documentation regarding clinical course, serial white blood cell counts, and the absence of serious infections, chronic illnesses, or a family history known to be associated with neutropenia. The median duration of documented neutropenia was 13 days (range, 1 to 491 days). Infectious complications occurred in 4 of the 36 patients who had neutropenia for more than 30 days (2 with stomatitis, 1 with cellulitis, and 1 with pneumonia) but in none with shorter durations of neutropenia. There were no significant associations between the development of an infectious complication and either the initial absolute neutrophil count or the lowest documented absolute neutrophil count, nor was there a correlation between the initial absolute neutrophil count and the duration of neutropenia. These data indicate that infectious complications occur in otherwise well children with unexplained neutropenia that persists, but these infections are infrequent and usually are superficial. 相似文献
3.
Leonidas JC; Berdon WE; Valderrama E; Neveling U; Schuval S; Weiss SJ; Hilfer C; Godine L 《Radiology》1996,198(2):377
4.
5.
D. Morse M. O'Shea G. Hamilton N. Soltanpoor G. Leece E. Miller D. Brown 《Epidemiology and infection》1994,113(2):355-365
An outbreak of measles occurred in a community school and the surrounding area in Crowborough, East Sussex, UK, from December 1992 to February 1993. There were 96 suspected cases reported: 66 cases among 1673 students at one school and 30 community cases. The majority of suspected cases were in those aged 11-17 (78%), 2 cases occurred in infants < 1 year old and 8 cases in adults aged 18 years or over. Data collected on 60 (91%) of the 66 suspect school cases showed 56 (93%) had an illness which met a case definition of measles. Eighteen had confirmatory IgM measles antibody. Two cases were hospitalized. The local percentage uptake for measles immunization for the school age years affected varied between 64% and 84%. A survey of parents showed that approximately 74% of the students attending the school had a history of measles immunization. The immunization rates reported by parents for children who developed measles was 21%, (29% based on GP records) compared with 77% for those who remained well. Vaccine efficacy was estimated to be 92%. This outbreak, along with others recently reported in older unimmunized children in the UK, reinforces the need for catch-up immunization programmes to reach this susceptible group of adolescents. 相似文献
6.
Rubella virus strains show no major antigenic differences. 总被引:7,自引:0,他引:7
To determine whether antigenic differences occur among rubella virus strains, five wild-type strains of rubella virus isolated in the UK, the USA, and in Japan between 1964 and 1987 and four attenuated vaccine strains were compared employing a panel of 28 monoclonal antibodies in neutralization, haemagglutination-inhibition, enzyme immunoassay, and indirect immunofluorescence assays. No antigenic differences were detected which confirms that rubella vaccines will protect against circulating strains and that rubella antigens used in serological tests for screening and diagnosis will detect antibodies induced by all strains. 相似文献
7.
8.
9.
10.