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Zouari IB Gouiaa N Charfi S Ellouze S Chaari C Kessentini M Hssini A Boudawara TS 《Annales de pathologie》2011,31(2):98-101
Uterine leiomyoma with massive lymphoid infiltration is a rare and unusual pathological finding; only 20 cases have been reported in the literature. We report a case of this unusual lesion in a 35-year-old woman who underwent a myomectomy. On gross examination, the tumor was of white color and firm consistency. Histological sections showed interlacing bundles of spindle shaped cells of low density with moderate to severe lymphocytic infiltrate associated to lymphoid follicles and few plasma cells. Immunohistochemically, the diffusely infiltrating lymphoid cells were predominantly of T cell phenotype. The interspersed spindle shaped cells were positive with alpha smooth muscle actin, desmin and h-caldesmon. The cause of this unusual lesion is not clear, but the recognition of its distinct histological features is important to avoid possible confusion with differential diagnosis including malignant lymphoma, inflammatory pseudotumor and pyomyoma. 相似文献
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Dr. Hazem Ben Ameur MD Haitham Rejab Salah Boujelbene Wala Ben Kridis Najla Abid Naoures Gouiaa Tahia Boudaouara Mounir Frikha Mohamed Issam Beyrouti 《memo - Magazine of European Medical Oncology》2013,6(2):149-152
Colon is a very rare site of metastasis from breast cancer. Its diagnosis is challenging. We report a new case of 56-year-old woman who was previously treated for lobular breast carcinoma 11 years ago. Radiologic features on barium enema and computed tomography (CT) were concordant with primary cancer of the transverse colon. The true diagnosis was made by immunohistochemical study of hemicolectomy specimen, which showed positivity for CA 15-3, cytokeratin 7, estrogen receptor, and progesterone receptor and negativity for cytokeratin 20 and carcinoembryonic antigen (CEA). The patient received chemotherapy and hormonal therapy. After a follow-up of 17 months, she is still alive with no evidence of recurrence. Literature review revealed that diagnosis should be suspected in the presence of bowel disorders in women with history of breast cancer even several years later. Surgery is beneficial in only isolated colonic metastasis. Otherwise, the treatment is based on systemic therapy. The prognosis is usually poor. 相似文献
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Sameh Ben Khedir Sana Bardaa Naourez Chabchoub Dorsaf Moalla Zouheir Sahnoun Tarek Rebai 《Pharmaceutical biology》2017,55(1):1407-1414
Context: Since antiquity, Pistacia lentiscus L. (Anacardiaceae) fruit oil (PLFO) has been used as a remedy for primary health care such as burn treatment.Objective: This study assesses the healing effect of PLFO on CO2 laser fractional burn in a rat model.Materials and methods: The study was carried out on 18 adult male Wistar rats. A second-degree laser burn (wound area?=?2.2?cm2) was inflicted in the dorsal region by the application of CO2 fractional laser within the following parameters; Energy level: 25?MJ and Depth level: 4. After applying laser, the rats were divided into three groups: the first was treated with saline solution, the second with a reference cream ‘CYTOL BASIC®’ (0.13?μg/mm2) and the third with PLFO (0.52?μL/mm2). All treatments were topically administered for eight days. The healing effect was assessed using macroscopic, histological and biochemical parameters.Results: After eight days, the higher percentage of wound healing contraction was observed among the PLFO-treated group (100%) followed by the ‘CYTOL BASIC®’ treated group (61.36%) and untreated group (32.27%). During the treatment, the PLFO-treated group showed less erythema, less crusting/scabbing, higher general wound appearance scores and a high content of collagen (220.67?±?7.48?mg/g of tissue) than the other groups.Discussion and conclusion: The current study has shown, for the first time, the healing effect of PLFO on CO2 laser fractional burn. Their wound healing effect could be attributed to their antimicrobial, anti-inflammatory and antioxidant effects. 相似文献
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A 3-month-old girl presented to the Department of Pediatric Surgery because of a strangled inguinal hernia. The exploration
using an inguinal approach showed a blue-reddish, moderately firm, circumscribed subcutaneous mass. Pathologic examination
of the resected tissue confirmed the diagnosis of capillary hemangioma. To the authors’ knowledge, this is the first reported
case of a capillary hemangioma occurring in this location. They provide a review of the current literature on capillary hemangiomas,
concluding that despite the rarity of these lesions, they should be considered in the differential diagnosis of lesions in
the inguinal location. 相似文献