全文获取类型
收费全文 | 992篇 |
免费 | 87篇 |
国内免费 | 28篇 |
专业分类
儿科学 | 61篇 |
妇产科学 | 12篇 |
基础医学 | 90篇 |
口腔科学 | 48篇 |
临床医学 | 132篇 |
内科学 | 238篇 |
皮肤病学 | 16篇 |
神经病学 | 16篇 |
特种医学 | 253篇 |
外科学 | 88篇 |
综合类 | 21篇 |
预防医学 | 35篇 |
眼科学 | 4篇 |
药学 | 53篇 |
肿瘤学 | 40篇 |
出版年
2023年 | 3篇 |
2021年 | 6篇 |
2020年 | 2篇 |
2019年 | 10篇 |
2018年 | 17篇 |
2017年 | 8篇 |
2016年 | 11篇 |
2015年 | 15篇 |
2014年 | 19篇 |
2013年 | 11篇 |
2012年 | 13篇 |
2011年 | 18篇 |
2010年 | 35篇 |
2009年 | 24篇 |
2008年 | 18篇 |
2007年 | 31篇 |
2006年 | 29篇 |
2005年 | 21篇 |
2004年 | 16篇 |
2003年 | 22篇 |
2002年 | 19篇 |
2001年 | 27篇 |
2000年 | 22篇 |
1999年 | 29篇 |
1998年 | 64篇 |
1997年 | 74篇 |
1996年 | 80篇 |
1995年 | 50篇 |
1994年 | 41篇 |
1993年 | 46篇 |
1992年 | 21篇 |
1991年 | 13篇 |
1990年 | 21篇 |
1989年 | 45篇 |
1988年 | 40篇 |
1987年 | 32篇 |
1986年 | 30篇 |
1985年 | 31篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1982年 | 12篇 |
1981年 | 10篇 |
1980年 | 13篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1977年 | 13篇 |
1976年 | 10篇 |
1975年 | 6篇 |
1966年 | 1篇 |
1950年 | 1篇 |
排序方式: 共有1107条查询结果,搜索用时 15 毫秒
1.
Isolated patellofemoral arthritis is an increasingly recognized entity, and is usually associated with previous patellofemoral dysplasia or instability. Patellofemoral arthroplasty (PFA) has evolved significantly in recent years, both in terms of implant design and importantly in the understanding of appropriate patient selection. This review outlines the indications and investigations for PFA, provides a brief history of the development of contemporary implants, and presents the clinical outcomes for the prostheses most commonly used in the UK. In addition, it provides a detailed surgical technique for implantation of an onlay implant, with tips on how to optimize patellofemoral biomechanics and thus achieve a consistently good outcome. 相似文献
2.
3.
Sonoelasticity imaging of prostate cancer: in vitro results 总被引:2,自引:0,他引:2
4.
5.
Abstract One hundred eighty-one consecutive patients with fulminant hepatic failure (FHF) presenting in a 2-year period were reviewed. In this cohort we examined the impact of pretransplant renal failure on mortality and morbidity following orthotopic liver transplantation (OLTx). Twenty-seven patients (18 female, 9 male) with a median age of 43.5 years (range 19–65 years) underwent OLTx. FHF was due to idiosyncratic drug reaction ( n = 4), paracetamol overdose ( n = 3), seronegative hepatitis ( n = 17), hepatitis B ( n = 1), veno-occlusive disease ( n = 1), and Wilson's disease ( n = 1). Renal failure was present in 14 patients, 7 of whom died (whereas there was 100 % survival in patients without renal failure). Pretransplant renal failure was associated with prolonged mechanical ventilation (13 days vs 6 days, P = 0.05), prolonged intensive care stay (17 days vs 8 days, P - 0.01) and prolonged hospital stay (27 vs 21 days, P = NS). Pretransplant renal failure did not predict renal dysfunction at 1 year after OLTx. We conclude that the survival of patients transplanted for FHF is inferior to that of patients transplanted for chronic liver disease (67 % vs 88 % 1-year survival in Birmingham). For patients with FHF undergoing transplantation, pretransplant renal failure strongly predicts poor outcome with significantly greater consumption of resources. 相似文献
6.
7.
8.
9.
Ten thrombocytopenic patients (platelets < 10–24 × 10(9)/L) who were refractory to platelet transfusion were investigated for their responsiveness to staphylococcal protein A column therapy. Nine patients had previously been treated with steroids, intravenous immune globulin, and/or other forms of immunosuppressive therapy without improvement in their transfusion response. All patients were receiving multiple platelet transfusions without achieving 1-hour corrected count increments (CCIs) > or = 7500. Eight patients had antibodies that reacted with platelets and were directed against HLA class I antigens, ABO antigens, and/or platelet-specific alloantigens. Plasma (500-2000 mL) from each patient was passed over a protein A silica gel column and then returned to the patient. Patients received from 1 to 14 treatments. A positive response to protein A therapy was defined as at least a doubling of the pretreatment platelet count and/or two successive 10- to 120-minute posttransfusion CCIs > or = 7500. Following plasma treatments, 6 of 10 patients responded with daily platelet counts that averaged 48 +/− 11 × 10(9) per L as compared with counts of 16 +/− 7 × 10(9) per L (p < 0.0005) before treatment. Posttransfusion CCI values determined in four of these patients averaged 2480 +/− 810 and 10,010 +/− 3540 (p < 0.005) before and after treatment, respectively. In contrast, among the four unresponsive patients, platelet counts averaged 10 +/− 9 and 13 +/− 10 × 10(9) per L (p = NS), respectively, while posttransfusion CCIs were 700 +/− 1410 and 1520 +/− 2460 (p = NS), respectively.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
10.
目的 探索LDH实验检测细胞活力的可行性。方法 原代培养骨髓细胞和软骨细胞,用LDH实验测定上述两组细胞的活力,并与镜下活体观察到细胞的生长状况相比较。与目前比较成熟的测定细胞活力的MTS实验的测得的值相比较。结果 LDH实验对上述两组细胞的活力的测定结果与镜下活体观察到的结果相符合。与MTS实验的测得的结果经统计学处理无显著差异。结论 LDH实验可用于细胞活力的直接测定,而对活细胞的生存、繁殖无影响。 相似文献