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Slouma Maroua Abbes Maissa Dhahri Rim Litaiem Noureddine Gueddiche Nour Mansouri Nada Msekni Issam Gharsallah Imen Metoui Leila Louzir Bassem 《Clinical rheumatology》2021,40(2):775-782
Clinical Rheumatology - Multiple endocrine neoplasia type 1 is a rare autosomal inherited syndrome that affects a variety of endocrine tissues such as the parathyroid, endocrine pancreas, and... 相似文献
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M. M. Hamdane F. Bougrine M. Ben Ammar I. Msekni M. Yedes A. Bouziani 《Journal africain du cancer / African Journal of Cancer》2012,4(4):228-232
Background
Central nervous tumors are the most common pediatric solid tumors. Because of their nonspecific symptoms, they are often diagnosed too late. The aim of this study is to evaluate diagnostic delay in pediatric central nervous system??s tumors.Methods
We analyzed retrospectively 63 cases of pediatric central nervous system tumors operated in the neurosurgery department of the Military Hospital of Tunis, over a period of 16 years patient who undergone surgeryResults
There were 38 boys and 25 girls with a mean age of 9 years. Most common signs were those of intracranial hypertension. Pre-diagnostic symptom interval ranged between 0 and 416 weeks with an average of 49 weeks and a median of 9 weeks. Only 39% of tumors were discovered within the first month after the onset of symptoms, while 32% of cases were diagnosed after 6 months. The median parental delay was 2 weeks with an average of 8 weeks and the median doctor??s delay was 2 weeks with an average of 37 weeks.Conclusion
Despite their frequency, CNS tumors are often diagnosed too late. A high level of awareness, a detailed medical history, repeated correctly interpreted neurological examinations and a respect of imaging indications should lead to an earlier diagnosis. 相似文献
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