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1.
Mieczysław Baryluk Gerard Obłonczek Jacek Żołnowski 《Archives of orthopaedic and trauma surgery》1977,87(1):65-71
Zusammenfassung Es wurden 30 Fälle der Kniegelenksmeniskusverletzung im Kindesalter vorgestellt, die operativ behandelt waren. 20 der Behandelten wurden nach 1–12 Jahren nach dem operativen Eingriff nachuntersucht. Es wurden n die Ätiologie, der Verletzungsmechanismus und der klinische Befund besprochen. Die klinische und radiologische Nachuntersuchung ermöglichte die morphologische und funktionelle Auswertung des Kniegelenks nach der Meniskusverletzung.
Injury of the semilunar cartilages of the knee-joint in childhood
Summary In the paper, 30 patients at the age of 5 till 14 with injuries of the semilunar cartilages of the knee-joint, are presented. All the children were subjected to surgery, and 20 of them underwent same examinations performed in a delay of 1 to 12 years after they had been operated. Both etiology and the injury mechanism subjects are hadled together with the clinical pictures, specific to the age of the young patients. Basing on the clinical and X-ray examinations, the state of the morphological and functional condition of the knee of a child after semilunar cartilage had been removed, was considered and estimated.相似文献
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3.
Paul M Stefaniak J Rychlicki W Kacprzak E Mazur-Roszak M Komarnicki M 《Wiadomo?ci parazytologiczne》2004,50(3):439-445
The incidence of non-specific reactions with E. multilocularis antigen in patients with liver malignancies, and the risk of a supradiagnosis of alveolar echinococcosis (AE) in space-occupying lesions in the liver due to neoplastic proliferative diseases were studied. Analysis of specific IgG serum antibody against Em2plus antigenic complex was performed in 11 AE patients in comparison to 76 individuals with malignant neoplasms of abdominal or extra-hepatic location, including some patients with primary hepatocellular cancer or distant metastases to liver, and 42 patients with benign hepatic lesions. Only one false borderline result was reported in a case with colorectal cancer, and dissemination to liver. Low risk of false positive results with E. multilocularis-specific Em2plus antigen in patients with liver malignancies makes the test valuable for practical reasons in a differential diagnosis of irregular tumor masses visualized by imaging techniques. 相似文献
4.
Pieniazek P Kabłak-Ziembicka A Pasowicz M Przewłocki T Zmudka K Moczulski Z Tracz W 《Kardiologia polska》2002,57(10):322-30; discussion 331
Carotid artery stenosis is one of the main causes of stroke. Nowadays two techniques for treating carotid stenosis are available - surgical endarterectomy and percutaneous angioplasty combined with stent implantation at the site of stenosis. Cerebral protection devices during internal carotid stenting significantly decrease the incidence of periprocedural complications, however, during the introduction of protective devices the cerebral blood flow remains unprotected. Therefore, the quest for a system specifically protecting cerebral flow during the whole procedure is still underway. Temporary reversal of carotid flow during the procedure using the Parodi Anti-Emboli System seems a viable solution. The present study describes the first two patients who underwent internal carotid artery stenting using this technique in our institution. 相似文献
5.
Undas A Szułdrzynski K Stepien E Zalewski J Godlewski J Tracz W Pasowicz M Zmudka K 《Atherosclerosis》2008,196(2):551-557
BackgroundStable angina is associated with unfavorable fibrin structure/function. It is not known how acute coronary syndromes (ACS) affect fibrin architecture.ObjectiveWe investigated fibrin clot properties and their determinants in ACS patients.Patients and methodsClot permeability, turbidity and fibrinolysis were assessed in 40 patients with ACS versus 40 controls with stable angina matched for age, sex, and risk factors.ResultsPatients with ACS had lower clot permeability (p = 0.001), faster fibrin polymerization (p = 0.008), and prolonged fibrinolysis time (p < 0.0001) than controls. C-reactive protein (CRP) and 8-epi-prostaglandin F2α, a marker of oxidative stress, were the only independent predictors of clot permeability (R2 = ?0.74; p < 0.0001 and R2 = ?0.65; p < 0.0001, respectively) and fibrinolysis time in ACS patients (R2 = 0.60; p < 0.0001 and R2 = 0.59; p = 0.0002, respectively). In angina patients, fibrinogen and CRP predicted permeability (R2 = ?0.71; p < 0.0001 and R2 = ?0.62; p < 0.0001), and D-dimer predicted lysis time (R2 = 0.54; p = 0.0005). In regression analysis models incorporating all patients, the only independent predictor of all clot variables was being an ACS patient (R2 0.51 to 0.85; p < 0.001).ConclusionsThis first study of clot properties in patients during an ACS demonstrated that compared with stable angina patients, their clots are composed of dense networks that are more resistant to lysis and these features are correlated with raised CRP and oxidative stress. 相似文献
6.
Agnieszka Szypowska Lidia Groele Marta Wysocka-Mincewicz Artur Mazur Lucyna Lisowicz Iwona Ben-Skowronek Joanna Sieniawska Bożenna Klonowska Dorota Charemska Jolanta Nawrotek Irena Jałowiec Artur Bossowski Klaudyna Noiszewska Beata Pyrżak Izabela Rogozińska Mieczysław Szalecki 《Journal of diabetes and its complications》2018,32(6):570-574
Aims
The level of C-peptide can identify individuals most likely to respond to immune interventions carried out to prevent pancreatic β-cell damage.The aim of the study was to evaluate factors associated with C-peptide levels at type 1 diabetes (T1D) diagnosis.Methods
This study included 1098 children aged 2-17 with newly recognized T1D. Data were collected from seven Polish hospitals. The following variables were analyzed: date of birth, fasting C-peptide, HbA1c, sex, weight, height, pH at diabetes onset.Results
A correlation was observed between fasting C-peptide level and BMI-SDS (p?=?0.0001), age (p?=?0.0001), and HbA1c (p?=?0.0001). The logistic regression model revealed that fasting C-peptide ≥0.7 ng/ml at diabetes diagnosis was dependent on weight, HbA1c, pH and sex (p?<?0.0001).Overweight and obese children (n?=?124) had higher fasting C-peptide (p?=?0.0001) and lower HbA1c (p?=?0.0008) levels than other subjects. Girls had higher fasting C-peptide (p?=?0.036) and higher HbA1c (p?=?0.026) levels than boys.Conclusion
Obese and overweight children are diagnosed with diabetes at an early stage with largely preserved C-peptide levels. Increased awareness of T1D symptoms as well as improved screening and diagnostic tools are important to preserve C-peptide levels. There are noticeable gender differences in the course of diabetes already at T1D diagnosis. 相似文献7.
Repeatable epiglottic movement patterns were recorded during a videofluoroscopic swallow evaluation of 95 patients who had
undergone a total or partial glossectomy due to a neoplasm. Because no epiglottic function assessment was performed preoperatively,
for the purpose of this study it was assumed that epiglottic mobility was “normal” during this time and that all abnormalities
found afterward resulted from the growth of the neoplasm and the glossectomy. It was noted that in the early postoperative
period, absence of epiglottic movement was accompanied by aspiration and made swallowing incompetent in a majority of cases
(9 of 10). A correlation of movement between the epiglottis and the extent of oral tissue excision was found. Epiglottic mobility
was evaluated as “normal” in 72% of the patients, i.e., in 67 of 91 (74%) patients after a partial or nearly total glossectomy
and in 1 of 4 people who underwent a total glossectomy. In the subgroup (16%) of patients who underwent a total or nearly
total glossectomy and then had videofluoroscopic examinations, 60% of the cases had normal epiglottic movements and 40% had
an immobile epiglottis. Compensatory mechanisms implemented by the patients on their own initiative, such as additional swallows
and prolonged apnea during deglutition, enabled them to avoid aspiration. However, upward head movement and downward chin
tilting during deglutition as compensatory mechanisms used by patients with no epiglottic movement did not reduce the aspiration
risk in the early postoperative period and were found to accompany incompetent swallowing attempts. 相似文献
8.
Background
Numerous studies have reported associations between air pollution and cardiovascular diseases. While several studies illustrate that exposures to air pollutants can elevate blood pressure, few have evaluated the clinical relevance of this relationship. Hence, we aimed to explore the associations between daily concentrations of several air pollutants and emergency department visits for hypertension.Methods
Odds ratios (ORs) for emergency department visits for hypertension in Edmonton, Canada, from April 1992 to March 2002 were associated with pollutant levels (CO, NO2, SO2, O3, and particulate matter [PM] < 10 microns [PM10] and < 2.5 microns [PM2.5] in aerodynamic diameter, respectively) by means of a case-crossover technique with time-stratified strategy to define controls. The analysis was performed for all (N = 5365), male (N = 2069), and female (N = 3296) patients and for six air pollutants lagged by 0 to 9 days. ORs and their 95% confidence intervals (CIs) were reported for an increase in an interquartile range (IQR) for each pollutant.Results
We observed associations for all patients and levels of NO2 (IQR = 12.8 parts per billion; OR, 1.06; 95% CI, 1.00-1.12), SO2 (IQR = 2.3 parts per billion; OR, 1.04; 95% CI, 1.00-1.08), and PM10 (IQR = 15.0 μg/m3; OR, 1.06; 95% CI, 1.01-1.11) for lag day 3, as well as for PM10 (IQR = 15.0 μg/m3; OR, 1.06; 95% CI, 1.01-1.11) and PM2.5 (IQR = 6.2 μg/m3; OR, 1.07; 95% CI, 1.01-1.11) for lag day 6.Conclusions
These findings support the contention that ambient pollution can produce clinically meaningful increases in blood pressure. 相似文献9.
Proton pump inhibitors are considered to be highly selective and effective drugs, which have few side effects. They are used in both adults and children (including infants) as well as in pregnant women. By increasing the gastric fluid pH, they impair the activation process and reduce the secretion of pepsin, secretin and pancreatic proteases, thereby impairing protein degradation. The remaining peptides are immunoreactive and lead to the development of an allergic response, while the increased permeability of the gastrointestinal tract mucosa may also induce sensitization. Observational studies conducted in patients with gastroenterological disorders, children with allergy diseases and experimental studies in animals have demonstrated that the use of anti-ulcer drugs favours sensitization to selected food allergens. 相似文献
10.
Tubulointerstitial nephritis with uveitis: clinico-pathological and immunological study 总被引:1,自引:0,他引:1
Litwin M Michałkiewicz J Jarmuek W Woźniewicz B Grenda R Iwanicka K Madaliński K 《Pediatric nephrology (Berlin, Germany)》2002,17(8):683-688
A 10-year-old boy was evaluated for fever, weight loss, uveitis, normocytic, normochromic anemia, renal insufficiency, and hypergammaglobulinemia of 8 weeks' duration. Infectious and neoplastic causes of fever were excluded. A renal biopsy performed in the 4th week of disease revealed diffuse plasmocytic interstitial nephritis. No treatment was prescribed and the patient was transferred to another hospital. Because clinical symptoms and renal insufficiency were still present, in the 8th week of disease a second biopsy was performed, which showed lympho-monocytic interstitial nephritis. At the same time, phenotypic analysis of peripheral blood mononuclear cells was carried out, revealing a significantly decreased number of CD3(+), CD4(+), and CD3(+)/CD8(+) cells, increased non-T CD3(-)/CD8(+) and CD56(+) NK cells, and decreased "na?ve" (CD45RA(+)/CD4(+)) and memory (CD45RO(+)/CD8(+)) T lymphocytes. A 6-month course of oral prednisone was prescribed. Clinical symptoms and laboratory findings quickly returned to normal values. After 13 days of corticosteroid therapy, a second phenotypic analysis of peripheral blood mononuclear cells was performed, which revealed normalization of CD3(+), CD4(+), and CD3(+)/CD8(+) cells as well as proportions of non-T CD8(+) and CD56(+) NK lymphocytes, "na?ve" and memory cells. This case shows spontaneous evolution of tubulointerstitial infiltrates from plasmacytic to lympho-monocytic, profound disturbances of the immunological system, and the beneficial effect of corticosteroids on both the clinical course and immunological disturbances. 相似文献