全文获取类型
收费全文 | 34253篇 |
免费 | 2486篇 |
国内免费 | 123篇 |
专业分类
耳鼻咽喉 | 396篇 |
儿科学 | 840篇 |
妇产科学 | 765篇 |
基础医学 | 4699篇 |
口腔科学 | 549篇 |
临床医学 | 3257篇 |
内科学 | 8000篇 |
皮肤病学 | 616篇 |
神经病学 | 3767篇 |
特种医学 | 1291篇 |
外国民族医学 | 4篇 |
外科学 | 5557篇 |
综合类 | 398篇 |
一般理论 | 9篇 |
预防医学 | 1976篇 |
眼科学 | 486篇 |
药学 | 2274篇 |
中国医学 | 95篇 |
肿瘤学 | 1883篇 |
出版年
2022年 | 232篇 |
2021年 | 505篇 |
2020年 | 308篇 |
2019年 | 530篇 |
2018年 | 647篇 |
2017年 | 495篇 |
2016年 | 558篇 |
2015年 | 720篇 |
2014年 | 930篇 |
2013年 | 1264篇 |
2012年 | 1935篇 |
2011年 | 2043篇 |
2010年 | 1269篇 |
2009年 | 1117篇 |
2008年 | 1915篇 |
2007年 | 2014篇 |
2006年 | 1877篇 |
2005年 | 1946篇 |
2004年 | 1896篇 |
2003年 | 1918篇 |
2002年 | 1809篇 |
2001年 | 686篇 |
2000年 | 656篇 |
1999年 | 651篇 |
1998年 | 502篇 |
1997年 | 415篇 |
1996年 | 372篇 |
1995年 | 366篇 |
1994年 | 308篇 |
1993年 | 331篇 |
1992年 | 489篇 |
1991年 | 468篇 |
1990年 | 406篇 |
1989年 | 410篇 |
1988年 | 405篇 |
1987年 | 401篇 |
1986年 | 399篇 |
1985年 | 325篇 |
1984年 | 324篇 |
1983年 | 291篇 |
1982年 | 225篇 |
1981年 | 192篇 |
1980年 | 179篇 |
1979年 | 239篇 |
1978年 | 145篇 |
1977年 | 169篇 |
1975年 | 131篇 |
1974年 | 148篇 |
1973年 | 165篇 |
1972年 | 133篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Renaud Snanoudj Nassim Kamar Elisabeth Cassuto Sophie Caillard Marie Metzger Pierre Merville Antoine Thierry Isabelle Jollet Philippe Grimbert Dany Anglicheau Marc Hazzan Gabriel Choukroun Bruno Hurault De Ligny Bénedicte Janbon Vincent Vuiblet Anne Devys Yann Le Meur Michel Delahousse Jean-Luc Taupin 《Kidney international》2019,95(6):1471-1485
2.
Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Sleep plays an important role in the regulation of central nervous system and body physiologic functions. Sleep architecture changes with age and is easily susceptible to external and internal disruption. Reduction or disruption of sleep can affect numerous functions varying from thermoregulation to learning and memory during the waking state. 相似文献
3.
A Michel C Vons S Hillaire P Icard G Hazebroucq F Kemeny D Houssin D Franco 《European surgical research. Europ?ische chirurgische Forschung. Recherches chirurgicales européennes》1990,22(5):249-255
The efficiency of Eurocollins or modified University of Wisconsin (UW) solution (MUW) in preserving rat livers was compared. After cold storage with one of the solutions, the livers were transplanted or perfused by collagenase for isolation of hepatocytes. Five of the 6 rats receiving a graft preserved with MUW versus none of the 6 rat receiving a graft preserved with Eurocollins solution survived 24 h or more. A significantly greater number of hepatocytes were isolated from livers preserved with MUW than from livers preserved with Eurocollins solution. This suggests a better reperfusion of MUW-preserved livers by collagenase resulting from less endothelial injury. LDH release by cultured hepatocytes, ketone body production and stimulation by glucagon were not significantly different between the two groups. These results confirm the superiority of MUW solution over Eurocollins in preserving liver grafts. They suggest that the advantage of MUW solution results from better protection of vascular endothelium rather than of hepatocytes. 相似文献
4.
P Brennan D Johnson S Rider N Cone M Goldman A Buckpitt H Chung 《Biopharmaceutics & drug disposition》1991,12(7):547-556
The dermal absorption of niclosamide, a drug shown to prevent Schistosomiasis by blocking the dermal penetration of cercariae, has been examined in Sinclair minipigs and rats. Radioactivity in the urine and feces collected daily for 7 days after application of 14C-niclosamide accounted for less than 2 per cent and 10 per cent of the labelled compound applied to pig and rat skin, respectively. Approximately 20 per cent of the radioactivity from the dose solution was recovered on the skin excised from the area of application in both minipigs and rats. No radioactivity was detected in organs removed from the pig 7 days after application of radiolabelled drug while less than 6 per cent of the dose could be accounted for in the rat organs/carcass. Radioactivity in swine blood, removed 0.5, 1, 2, 4 and at 24 h intervals after dosing, was at or below three times background in all of the samples. Total recovery of the applied radioactivity was 78 per cent in pigs and 57 per cent in rats. These studies indicate that niclosamide is very poorly absorbed after dermal application. The results are consistent with earlier comparative studies showing that dermal penetration of xenobiotics in rats is generally higher than in swine. 相似文献
5.
Marie-Paule Roth Hlne Coppin Patrick Descoins Jean-Bernard Ruidavets Anne Cambon-Thomsen Michel Clanet 《Journal of neuroimmunology》1991,34(2-3):215-222
The polymorphism at the HLA-DPB1 locus has been characterized in a large number of patients with multiple sclerosis (n = 112) and in healthy controls (n = 115). Both patients and controls lived in the southwest of France (in the Pyrénées Atlantiques) and had similar ethnic background. The typing procedure involved the selective amplification of the second exon of the DPB1 locus by polymerase chain reaction, followed by hybridization of the amplified DNA with 14 sequence-specific oligonucleotide probes. Individual alleles were identified by the pattern of hybridization of the different probes. The distribution of the DPB1 alleles was not significantly different in multiple sclerosis patients and controls (p = 0.11). This does not corroborate the reported association of multiple sclerosis with the primed lymphocyte typing (PLT)-defined DPw4 specificity and is not in favour of a role played by polymorphic residues of the DP molecule in susceptibility to multiple sclerosis. 相似文献
6.
7.
A 68 year-old woman presented with a two-week history of amaurosis fugax, ipsilateral fronto-temporal headache and jaw claudication suggesting carotid giant cell arteritis. However, this syndrome proved to be due to atherosclerosis causing complete occlusion of the external carotid artery at its origin and narrowing of the internal carotid artery. Combined external and internal carotid endarterectomy relieved the symptoms. The symptom complex of temporal arteritis may be rarely mimicked by carotid atherosclerotic occlusive disease. 相似文献
8.
Aaron M Kipp Jennifer A Lehman Richard A Bowen Patricia E Fox Michael R Stephens Kaci Klenk Nicholas Komar Michel L Bunning 《The American journal of tropical medicine and hygiene》2006,75(4):688-690
To better understand the potential environmental health risk presented by West Nile virus (WNV)-contaminated feces, we quantified the amount of WNV present in the feces of experimentally infected American crows (Corvus brachyrhynchos) and fish crows (Corvus ossifragus). Peak fecal titers ranged from 10(3.5) to 10(8.8) plaque-forming units (PFU)/g for 10 American crows and from 10(2.3) to 10(6.4) PFU/g for 10 fish crows. The presence of infectious WNV in bird feces indicates a potential for direct transmission of WNV. Thus, handlers of sick or dead birds should take appropriate precautions to avoid exposure to fecal material. 相似文献
9.
10.