全文获取类型
收费全文 | 1807篇 |
免费 | 147篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 43篇 |
儿科学 | 111篇 |
妇产科学 | 13篇 |
基础医学 | 184篇 |
口腔科学 | 32篇 |
临床医学 | 237篇 |
内科学 | 418篇 |
皮肤病学 | 34篇 |
神经病学 | 111篇 |
特种医学 | 268篇 |
外科学 | 155篇 |
综合类 | 29篇 |
一般理论 | 1篇 |
预防医学 | 68篇 |
眼科学 | 35篇 |
药学 | 99篇 |
中国医学 | 5篇 |
肿瘤学 | 118篇 |
出版年
2023年 | 11篇 |
2021年 | 17篇 |
2020年 | 16篇 |
2019年 | 17篇 |
2018年 | 40篇 |
2017年 | 19篇 |
2016年 | 25篇 |
2015年 | 31篇 |
2014年 | 44篇 |
2013年 | 37篇 |
2012年 | 42篇 |
2011年 | 56篇 |
2010年 | 58篇 |
2009年 | 66篇 |
2008年 | 58篇 |
2007年 | 34篇 |
2006年 | 35篇 |
2005年 | 30篇 |
2004年 | 38篇 |
2003年 | 34篇 |
2002年 | 32篇 |
2001年 | 45篇 |
2000年 | 35篇 |
1999年 | 36篇 |
1998年 | 61篇 |
1997年 | 64篇 |
1996年 | 81篇 |
1995年 | 57篇 |
1994年 | 49篇 |
1993年 | 53篇 |
1992年 | 45篇 |
1991年 | 41篇 |
1990年 | 35篇 |
1989年 | 59篇 |
1988年 | 56篇 |
1987年 | 58篇 |
1986年 | 57篇 |
1985年 | 39篇 |
1984年 | 44篇 |
1983年 | 35篇 |
1982年 | 34篇 |
1981年 | 25篇 |
1980年 | 23篇 |
1979年 | 19篇 |
1978年 | 21篇 |
1977年 | 19篇 |
1976年 | 15篇 |
1975年 | 25篇 |
1970年 | 11篇 |
1969年 | 15篇 |
排序方式: 共有1961条查询结果,搜索用时 15 毫秒
1.
ME BURGE AM JOSHUA CM McNEIL R HUI MJ BOYER R ABRAHAM 《Asia-Pacific Journal of Clinical Oncology》2005,1(1):47-52
Background: Pemetrexed and cisplatin have recently been shown to significantly improve survival compared with cisplatin alone. However, there are only limited data reflecting teaching hospital experience outside a clinical trial. Pemetrexed has only been available in Australia on a restricted basis since 2002. We reviewed our experience of patients treated on the Australian ‘Special Access Scheme’ at three major thoracic oncology units. Methods: Charts were reviewed for all patients enrolled on the scheme. Data was extracted on age, World Health Organization (WHO) performance status, histology, prior therapy, time from diagnosis to starting pemetrexed, chemotherapy (pemetrexed alone or with a platinum), cycle number, response rate, actuarial progression‐free and overall survival. Doses were cisplatin 75 mg/m2 or carboplatin AUC = 5 and pemetrexed 500 mg/m2 every 21 days. Results: 52 patients (32 male and 20 female) were reviewed. Median age was 58 years and 88% were WHO 0–1. Histology included 54% epithelial, 17% biphasic (epithelial and sarcomatoid) and 21% undefined. The median time from diagnosis to administration of pemetrexed was 145 days. Sixty‐five percent had minimal surgical intervention with video assisted thoracoscopy, pleurodesis and biopsy, while 19% had received prior palliative radiation. Seventy‐one percent were chemotherapy naïve, the remaining 29% having received previous platinum and/or gemcitabine regimens. Twenty‐three percent had pemetrexed alone, 35% in combination with carboplatin and 42% with cisplatin. The median number of cycles was 4 (range 1–13). The response rate was 33%. No toxicity was observed in 20% grade 3–4 toxicity in 10% (majority nausea/vomiting). The median progression‐free and overall survival times from starting pemetrexed were 184 days and 298 days, respectively. Conclusions: Pemetrexed‐based regimens are safe and effective in a community setting in malignant mesothelioma. 相似文献
2.
3.
4.
5.
6.
7.
8.
9.
10.
H Shonna Yin Benard P Dreyer George Foltin Linda van Schaick Alan L Mendelsohn 《Ambulatory Pediatrics》2007,7(4):292-298
OBJECTIVE: Caregivers of young children frequently measure doses of liquid medications incorrectly. Use of nonstandardized dosing instruments and lack of knowledge that dosing is weight-based contribute to dosing errors. We sought to assess whether low caregiver health literacy was associated with these outcomes. METHODS: This was a cross-sectional analysis of caregivers presenting to an urban pediatric emergency room. Dependent variables were caregiver reported use of nonstandardized dosing tools and knowledge of weight-based dosing. The independent variable was caregiver health literacy (Test of Functional Health Literacy in Adults [TOFHLA]). RESULTS: Two hundred ninety-two caregivers were assessed: 23.3% reported use of nonstandardized liquid dosing instruments, and 67.8% were unaware of weight-based dosing. Caregivers who were unaware of weight-based dosing were more likely to use nonstandardized dosing tools (28.3% vs 12.8%; P = .003). In unadjusted analyses, overall health literacy, reading comprehension, and numeracy were all associated with both dependent variables. In analyses adjusting for child age, health care experiences, and caregiver acculturation and education, inadequate/marginal overall health literacy was associated with lack of knowledge of weight-based dosing (adjusted odds ratio [AOR] 2.3; P = .03), whereas lower reading comprehension was associated with both lack of knowledge (AOR 2.0; P = .03) and reported use of nonstandardized instrument (AOR 2.4; P = .007). CONCLUSIONS: Low health literacy, in particular reading comprehension, was associated with reported use of nonstandardized dosing instruments and lack of knowledge regarding weight-based dosing. Both caregiver health literacy and sociodemographic factors should be considered in the design of interventions to prevent medication administration errors. 相似文献