全文获取类型
收费全文 | 1568篇 |
免费 | 131篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 113篇 |
妇产科学 | 15篇 |
基础医学 | 240篇 |
口腔科学 | 32篇 |
临床医学 | 192篇 |
内科学 | 322篇 |
皮肤病学 | 68篇 |
神经病学 | 109篇 |
特种医学 | 138篇 |
外科学 | 195篇 |
综合类 | 49篇 |
预防医学 | 97篇 |
眼科学 | 33篇 |
药学 | 51篇 |
肿瘤学 | 48篇 |
出版年
2023年 | 7篇 |
2022年 | 20篇 |
2021年 | 29篇 |
2020年 | 25篇 |
2019年 | 28篇 |
2018年 | 54篇 |
2017年 | 28篇 |
2016年 | 42篇 |
2015年 | 51篇 |
2014年 | 63篇 |
2013年 | 77篇 |
2012年 | 65篇 |
2011年 | 57篇 |
2010年 | 66篇 |
2009年 | 73篇 |
2008年 | 49篇 |
2007年 | 55篇 |
2006年 | 38篇 |
2005年 | 40篇 |
2004年 | 34篇 |
2003年 | 33篇 |
2002年 | 39篇 |
2001年 | 41篇 |
2000年 | 24篇 |
1999年 | 31篇 |
1998年 | 47篇 |
1997年 | 51篇 |
1996年 | 53篇 |
1995年 | 44篇 |
1994年 | 29篇 |
1993年 | 40篇 |
1992年 | 25篇 |
1991年 | 33篇 |
1990年 | 21篇 |
1989年 | 37篇 |
1988年 | 25篇 |
1987年 | 23篇 |
1986年 | 21篇 |
1985年 | 15篇 |
1984年 | 12篇 |
1983年 | 16篇 |
1982年 | 9篇 |
1981年 | 13篇 |
1980年 | 9篇 |
1979年 | 5篇 |
1978年 | 11篇 |
1977年 | 8篇 |
1976年 | 13篇 |
1975年 | 5篇 |
1973年 | 7篇 |
排序方式: 共有1708条查询结果,搜索用时 15 毫秒
1.
2.
Congenital herpes simplex retinitis 总被引:2,自引:0,他引:2
An 1,810-g girl born at 37 weeks of gestation had true congenital herpes simplex virus type 2 infection. The neonate was born with hypo-pigmented skin lesions, brain lesions, and old heavily pigmented retinal scars in the posterior pole. There was no active ocular disease. Viral cultures, immunoperoxidase stains, and antibody determination by enzyme-linked immunosorbent assay were all positive for herpes simplex virus. Treatment with acyclovir healed the lesions within ten days. The clinical and laboratory findings indicated that the herpetic infection probably occurred in the second trimester. 相似文献
3.
Since 1990, lung transplantation has been performed in infants, children and adolescents in small numbers, and the numbers, in comparison with adult transplants, remain small today. The indications for lung transplantation are similar in childhood when compared with adults, but the disease entities are distinct. In children, severe pulmonary vascular disease is most commonly associated with developmental abnormalities or congenital heart disease, as opposed to idiopathic pulmonary hypertension. Cystic fibrosis is the dominant indication for lung transplantation in older childhood and adolescence. The operative approach to lung transplantation in early life differs from that in adults, in that cardiopulmonary bypass is more likely to be utilised and bilateral lung transplantation is strongly preferred to single lung transplantation. Living donor lung transplantation is proportionately more common in children and adolescents than in adults. Post-transplant complications related to viral infection and post-transplant lymphoproliferative disease are more common and more likely to be severe and life-threatening. Bronchiolitis obliterans is the most important complication after paediatric lung transplantation and limits both the quality of life and duration of survival, as in adults. 相似文献
4.
5.
We have described two children with multiple cutaneous granular cell tumors (GCT) and have reviewed the literature. Multiple tumors of the skin are relatively rare, especially in children, with only 18 pediatric cases previously reported. Surgical excision of rapidly growing or symptomatic lesions is the treatment of choice. In these two children with multiple GCT, three lesions were excised. Specific stains for enolase and S-100 protein clearly demarcated tumor margins after surgical excision. Despite intensive investigation, the histogenesis of this tumor is still in dispute. The most tenable theory at this time is that these tumors are derived either directly from Schwann cells or from undifferentiated cells developing neural characteristics. 相似文献
6.
Linda G. Rabinowitz M.D. Nancy B Esterly M.D. Ilona J. Frieden M.D. Gregory S. Garbin M.D. Roy C. Grekin M.D. T. J. Stafford M.D. Ph.D. O. T. Tan M.D. Linda G. Rabinowitz M.D. Gerald N. Goldberg M.D. Karen F Rothman M.D. Lynne J. Roberts M.D. Roy G. Geronemus M.D. Susan B. Mallory M.D. Jerome M. Garden M.D. Joseph G. Morelli M.D. Moise L Levy M.D. Bernard A. Cohen M.D. 《Pediatric dermatology》1992,9(2):132-153
One of the most exciting developments in pediatric dermatology has been the use of the flashlamp-pumped, 585-nm, pulsed dye laser for treatment of vascular birthmarks. In many cases the results are miraculous. The increase in self-esteem and happiness of many children and adolescents has been overwhelming; for some, depression has been lifted, stuttering has ceased, social involvement has increased, and antidepressants have been discontinued. There are many success stories to tell.
Despite the remarkable effects of the pulsed dye laser and the medical and psychosocial indications for its use, the issue of pain control remains significant. We have no perfect outpatient pediatric anesthetic. Most methods carry either some risk or, if not hazardous, often are not very effective for controlling pain. Needless to say, a diversity of opinions exist on how to manage discomfort from this treatment modality. Therefore, we thought it would be useful to share the experiences and opinions of several dermatologists who have extensive experience with the pulsed dye laser. 相似文献
Despite the remarkable effects of the pulsed dye laser and the medical and psychosocial indications for its use, the issue of pain control remains significant. We have no perfect outpatient pediatric anesthetic. Most methods carry either some risk or, if not hazardous, often are not very effective for controlling pain. Needless to say, a diversity of opinions exist on how to manage discomfort from this treatment modality. Therefore, we thought it would be useful to share the experiences and opinions of several dermatologists who have extensive experience with the pulsed dye laser. 相似文献
7.
8.
9.
10.
Silber SJ; Nagy Z; Devroey P; Tournaye H; Van Steirteghem AC 《Human reproduction (Oxford, England)》1997,12(11):2422-2428
The aim of the study was to determine whether a prior diagnostic testicle
biopsy can predict success or failure of testicular sperm extraction (TESE)
with intracytoplasmic sperm injection (ICSI) in patients with
non-obstructive azoospermia caused by testicular failure, and what is the
minimum threshold of sperm production in the testis which must be surpassed
for spermatozoa to reach the ejaculate. Forty- five patients with
non-obstructive azoospermia caused by testicular failure underwent
diagnostic testicle biopsy prior to a planned future TESE-ICSI procedure.
The diagnostic testicle biopsy was analysed quantitatively, and correlated
with the quantitative findings of spermatogenesis in patients with normal
spermatogenesis, as well as with the results of subsequent attempts at
TESE-ICSI. Men with non- obstructive azoospermia caused by germinal failure
had a mean of 0-6 mature spermatids/seminiferous tubule seen on a
diagnostic testicle biopsy, compared to 17-35 mature spermatids/tubule in
men with normal spermatogenesis and obstructive azoospermia. These findings
were the same for all types of testicular failure whether Sertoli cell
only, maturation arrest, cryptorchidism, or post-chemotherapy azoospermia.
Twenty-two of 26 men with mature spermatids found in the prior testis
biopsy had successful retrieval of spermatozoa for ICSI, 12 of their
partners became pregnant, and are either ongoing or delivered. The study
suggests that 4-6 mature spermatids/tubule must be present in the testis
biopsy for any spermatozoa to reach the ejaculate. More than half of
azoospermic patients with germinal failure have minute foci of
spermatogenesis which are insufficient to produce spermatozoa in the
ejaculate. Prior diagnostic testicle biopsy analysed quantitatively (for
the presence of mature spermatids) can predict subsequent success or
failure with TESE-ICSI. Incomplete testicular failure may involve a sparse
multi-focal distribution of spermatogenesis throughout the entire testicle,
rather than a regional distribution. Therefore, it is possible that massive
testicular sampling from many different regions of the testes may not be
necessary for successful TESE-ICSI.
相似文献