全文获取类型
收费全文 | 2591篇 |
免费 | 231篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 116篇 |
妇产科学 | 109篇 |
基础医学 | 325篇 |
口腔科学 | 45篇 |
临床医学 | 249篇 |
内科学 | 456篇 |
皮肤病学 | 48篇 |
神经病学 | 78篇 |
特种医学 | 322篇 |
外科学 | 473篇 |
综合类 | 102篇 |
预防医学 | 193篇 |
眼科学 | 32篇 |
药学 | 116篇 |
中国医学 | 9篇 |
肿瘤学 | 151篇 |
出版年
2022年 | 10篇 |
2021年 | 23篇 |
2020年 | 15篇 |
2019年 | 34篇 |
2018年 | 35篇 |
2017年 | 25篇 |
2016年 | 21篇 |
2015年 | 46篇 |
2014年 | 76篇 |
2013年 | 108篇 |
2012年 | 100篇 |
2011年 | 120篇 |
2010年 | 87篇 |
2009年 | 92篇 |
2008年 | 98篇 |
2007年 | 117篇 |
2006年 | 94篇 |
2005年 | 88篇 |
2004年 | 96篇 |
2003年 | 85篇 |
2002年 | 97篇 |
2001年 | 86篇 |
2000年 | 82篇 |
1999年 | 92篇 |
1998年 | 96篇 |
1997年 | 63篇 |
1996年 | 84篇 |
1995年 | 66篇 |
1994年 | 61篇 |
1993年 | 59篇 |
1992年 | 51篇 |
1991年 | 32篇 |
1990年 | 35篇 |
1989年 | 72篇 |
1988年 | 44篇 |
1987年 | 47篇 |
1986年 | 35篇 |
1985年 | 33篇 |
1984年 | 22篇 |
1983年 | 27篇 |
1982年 | 22篇 |
1981年 | 29篇 |
1980年 | 18篇 |
1979年 | 11篇 |
1978年 | 12篇 |
1977年 | 27篇 |
1976年 | 14篇 |
1975年 | 23篇 |
1974年 | 18篇 |
1967年 | 11篇 |
排序方式: 共有2838条查询结果,搜索用时 15 毫秒
1.
Williamson Kathleen A.; Hever Ann M.; Rainger Joe; Rogers R. Curtis; Magee Alex; Fiedler Zdenek; Keng Wee Teik; Sharkey Freddie H.; McGill Niolette; Hill Clare J.; Schneider Adele; Messina Mario; Turnpenny Peter D.; Fantes Judy A.; van Heyningen Veronica; FitzPatrick David R. 《Human molecular genetics》2006,15(12):2030
Table 1 相似文献
2.
目的 探讨创伤后迟发性脑肿胀的临床特点、发病机制与治疗。方法 回顾性分析1998年1月~2005年6月年收治的17例迟发性脑肿胀患者的临床特点和救治情况。结果 所有颅脑损伤患者采用保守治疗后均有好转,但于伤后5-10d出现恶化,CT复查有脑肿胀,经加强综合脱水等治疗后16例治愈,1例死亡。结论 迟发性脑肿胀好发于对冲性额、颞叶挫裂伤伴明显蛛网膜下腔出血、硬膜下薄层血肿及早期CT有脑肿胀者。其发病机制可能与创伤后的迟发性脑血管痉挛、微循环障碍、静脉回流障碍及甘露醇作用下降等因素有关。此类患者病情隐蔽性强,应加强观察、积极行CT复查,如能早期明确诊断,保守治疗多数效果良好。 相似文献
3.
Reduced blood clearance and increased urinary excretion of N-nitrosodimethylamine in patas monkeys exposed to ethanol or isopropyl alcohol. 总被引:1,自引:0,他引:1
L M Anderson R Koseniauskas E S Burak T J Moskal C T Gombar J M Phillips E B Sansone S Keimig P N Magee J M Rice 《Cancer research》1992,52(6):1463-1468
Low concentrations of N-nitrosodimethylamine are metabolized in rodent and human liver by cytochrome P450IIE1, an activity competitively inhibitable by ethanol. In rodents coadministration of ethanol with N-nitrosodimethylamine results in increased tumorigenicity in extrahepatic organs, probably as a result of reduced hepatic clearance. To test this concept in a primate, the effects of ethanol cotreatment on the pharmacokinetics of N-nitrosodimethylamine were measured in male patas monkeys. Ethanol, 1.2 g/kg given p.o. before i.v. N-nitrosodimethylamine (1 mg/kg) or concurrently with an intragastric dose resulted in a 10-50-fold increase in the area under the blood concentration versus time curves and a 4-13-fold increase in mean residence times for N-nitrosodimethylamine. Isopropyl alcohol, 3.2 g/kg 24 h before N-nitrosodimethylamine, also increased these parameters 7-10-fold; this effect was associated with persistence of isopropyl alcohol and its metabolic product acetone, both IIE1 inhibitors, in the blood. While no N-nitrosodimethylamine was detected in expired air, trace amounts were found in urine. Ethanol and isopropyl alcohol pretreatment increased the maximum urinary N-nitrosodimethylamine concentration 15-50-fold and the percentage of the dose excreted in the urine by 100-800-fold. Thus ethanol and isopropyl alcohol greatly increase systemic exposure of extrahepatic organs to N-nitrosodimethylamine in a primate. 相似文献
4.
Retrorenal colon: implications for percutaneous diskectomy 总被引:1,自引:0,他引:1
It has been recommended that computed tomography (CT) with the patient prone be performed in every patient undergoing percutaneous diskectomy; this would enable detection of a retrorenal location of the colon, which could interfere with the percutaneous procedure. In this evaluation of 346 prone CT studies, only one patient (0.29%) was found to have retrorenal or retropsoas bowel that would have been perforated at diskectomy. Because of this extremely low prevalence, the performance of prone CT in every patient undergoing percutaneous lumbar diskectomy is not believed to be necessary. 相似文献
5.
6.
7.
8.
S. J. Pelletier M. K. Guidinger R. M. Merion M. J. Englesbe R. A. Wolfe J. C. Magee H. W. Sollinger 《American journal of transplantation》2006,6(7):1646-1652
The optimal use of kidneys from small pediatric deceased donors remains undetermined. Using data from the Scientific Registry of Transplant Recipients, 2886 small (< 21 kg) pediatric donors between 1993 and 2002 were identified. Donor factors predictive of kidney recovery and transplantation (1343 en bloc; 1600 single) were identified by logistic regression. Multivariable Cox regression was used to assess the risk of graft loss. The rate of kidney recovery from small pediatric donors was significantly higher with increasing age, weight and height. The odds of transplant of recovered small donor kidneys were significantly higher with increasing age, weight, height and en bloc recovery (adjusted odds ratio = 65.8 vs. single; p < 0.0001), and significantly lower with increasing creatinine. Compared to en bloc, solitary transplants had a 78% higher risk of graft loss (p < 0.0001). En bloc transplants had a similar graft survival to ideal donors (p = 0.45) while solitary transplants had an increased risk of graft loss (p < 0.0001). En bloc recovery of kidneys from small pediatric donors may result in the highest probability of transplantation. Although limited by the retrospective nature of the study, kidneys transplanted en bloc had a similar graft survival to ideal donors but may not maximize the number of successfully transplanted recipients. 相似文献
9.
Video-assisted thoracic surgery: basic technical concepts and intercostal approach strategies. 总被引:5,自引:0,他引:5
R J Landreneau M J Mack S R Hazelrigg R D Dowling T E Acuff M J Magee P F Ferson 《The Annals of thoracic surgery》1992,54(4):800-807
Video-assisted thoracic surgery is emerging as a viable approach to a number of intrathoracic disorders. Technical difficulties related to improper instrument selection and suboptimal intercostal operative access can reduce the utility of, and the enthusiasm for, the video-assisted thoracic surgical approach. This report describes the intercostal access strategy and the instrument positioning that we now prescribe for many video-assisted thoracic surgical procedures. These approaches have become refined during the course of our experience with 467 patients undergoing video-assisted thoracic operations over the last 18 months. 相似文献
10.
郭永建 《福建医科大学学报》1994,(1)
采用间接ELISA检测23名肾移植受者血清巨细胞病毒(CMV)抗体,共检出18名(78%)活动性CMV感染,其中10名(44%)为原发性感染。结果证实CMV-IgE和-IgA具有较好的血清学诊断价值,优于CMV-IgM。 相似文献