全文获取类型
收费全文 | 309342篇 |
免费 | 15602篇 |
国内免费 | 2340篇 |
专业分类
耳鼻咽喉 | 4136篇 |
儿科学 | 8567篇 |
妇产科学 | 8125篇 |
基础医学 | 45544篇 |
口腔科学 | 9405篇 |
临床医学 | 21473篇 |
内科学 | 63400篇 |
皮肤病学 | 7569篇 |
神经病学 | 23325篇 |
特种医学 | 9050篇 |
外国民族医学 | 23篇 |
外科学 | 39023篇 |
综合类 | 7263篇 |
现状与发展 | 1篇 |
一般理论 | 60篇 |
预防医学 | 29942篇 |
眼科学 | 7608篇 |
药学 | 24817篇 |
6篇 | |
中国医学 | 2079篇 |
肿瘤学 | 15868篇 |
出版年
2022年 | 1667篇 |
2021年 | 4439篇 |
2020年 | 2606篇 |
2019年 | 4607篇 |
2018年 | 7485篇 |
2017年 | 4936篇 |
2016年 | 4921篇 |
2015年 | 5668篇 |
2014年 | 6660篇 |
2013年 | 9551篇 |
2012年 | 15450篇 |
2011年 | 16224篇 |
2010年 | 8696篇 |
2009年 | 6850篇 |
2008年 | 13401篇 |
2007年 | 14358篇 |
2006年 | 13863篇 |
2005年 | 12986篇 |
2004年 | 11995篇 |
2003年 | 11283篇 |
2002年 | 10678篇 |
2001年 | 12319篇 |
2000年 | 13101篇 |
1999年 | 10542篇 |
1998年 | 2848篇 |
1997年 | 2106篇 |
1992年 | 6284篇 |
1991年 | 6109篇 |
1990年 | 5815篇 |
1989年 | 5489篇 |
1988年 | 5325篇 |
1987年 | 5024篇 |
1986年 | 4849篇 |
1985年 | 4635篇 |
1984年 | 3215篇 |
1983年 | 2780篇 |
1979年 | 3185篇 |
1978年 | 2026篇 |
1977年 | 1818篇 |
1976年 | 1709篇 |
1975年 | 2070篇 |
1974年 | 2502篇 |
1973年 | 2555篇 |
1972年 | 2477篇 |
1971年 | 2302篇 |
1970年 | 2143篇 |
1969年 | 2202篇 |
1968年 | 2145篇 |
1967年 | 1881篇 |
1966年 | 1697篇 |
排序方式: 共有10000条查询结果,搜索用时 9 毫秒
1.
2.
3.
Jose M. Morales Jose Angel Martinez-Flores Manuel Serrano Maria José Castro Francisco Javier Alfaro Florencio García Miguel Angel Martínez Amado Andrés Esther González Manuel Praga Estela Paz-Artal Antonio Serrano 《Journal of the American Society of Nephrology : JASN》2015,26(3):735-745
In the current immunosuppressive therapy era, vessel thrombosis is the most common cause of early graft loss after renal transplantation. The prevalence of IgA anti–β2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patients on dialysis is elevated (>30%), and these antibodies correlate with mortality and cardiovascular morbidity. To evaluate the effect of IgA-aB2GPI-ab in patients with transplants, we followed all patients transplanted from 2000 to 2002 in the Hospital 12 de Octubre prospectively for 10 years. Presence of IgA-aB2GPI-ab in pretransplant serum was examined retrospectively. Of 269 patients, 89 patients were positive for IgA-aB2GPI-ab (33%; group 1), and the remaining patients were negative (67%; group 2). Graft loss at 6 months post-transplant was significantly higher in group 1 (10 of 89 versus 3 of 180 patients in group 2; P=0.002). The most frequent cause of graft loss was thrombosis of the vessels, which was observed only in group 1 (8 of 10 versus 0 of 3 patients in group 2; P=0.04). Multivariate analysis showed that the presence of IgA-aB2GPI-ab was an independent risk factor for early graft loss (P=0.04) and delayed graft function (P=0.04). There were no significant differences regarding patient survival between the two groups. Graft survival was similar in both groups after 6 months. In conclusion, patients with pretransplant IgA-aB2GPI-ab have a high risk of early graft loss caused by thrombosis and a high risk of delayed graft function. Therefore, pretransplant IgA-aB2GPI-ab may have a detrimental effect on early clinical outcomes after renal transplantation. 相似文献
4.
5.
6.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献
7.
8.
9.
10.
Rosario Gulias-Cañizo Anell Lagunes-Guillén Arturo González-Robles Erika Sánchez-Guzmán Federico Castro-Muñozledo 《Burns : journal of the International Society for Burn Injuries》2019,45(2):398-412