全文获取类型
收费全文 | 557篇 |
免费 | 31篇 |
国内免费 | 3篇 |
专业分类
儿科学 | 17篇 |
妇产科学 | 22篇 |
基础医学 | 69篇 |
口腔科学 | 3篇 |
临床医学 | 40篇 |
内科学 | 121篇 |
皮肤病学 | 12篇 |
神经病学 | 62篇 |
特种医学 | 7篇 |
外科学 | 60篇 |
预防医学 | 79篇 |
眼科学 | 2篇 |
药学 | 38篇 |
肿瘤学 | 59篇 |
出版年
2024年 | 3篇 |
2023年 | 12篇 |
2022年 | 21篇 |
2021年 | 45篇 |
2020年 | 20篇 |
2019年 | 37篇 |
2018年 | 23篇 |
2017年 | 23篇 |
2016年 | 28篇 |
2015年 | 33篇 |
2014年 | 40篇 |
2013年 | 46篇 |
2012年 | 69篇 |
2011年 | 53篇 |
2010年 | 27篇 |
2009年 | 19篇 |
2008年 | 26篇 |
2007年 | 20篇 |
2006年 | 12篇 |
2005年 | 12篇 |
2004年 | 1篇 |
2003年 | 7篇 |
2002年 | 6篇 |
1999年 | 1篇 |
1998年 | 1篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 2篇 |
1994年 | 1篇 |
1993年 | 1篇 |
排序方式: 共有591条查询结果,搜索用时 15 毫秒
1.
2.
Marco Caldin Tommaso Furlanello Laia Solano-Gallego Davide De Lorenzi Erika Carli Silvia Tasca George Lubas 《Comparative clinical pathology》2005,14(1):5-12
Donkeys, an endangered species, have recently gained a new application with the use of their milk to feed humans with allergic processes. The Ragusana donkey breed from Sicily is used to produce milk for humans with allergic diseases. In order to evaluate the hygienic, nutritional and management measures on a farm of Ragusana donkeys, complete blood counts, extended biochemical profiles and serum protein electrophoresis, as part of metabolic profile test (MPT), were performed in Ragusana donkeys. Fifty-four donkeys were studied and grouped according to their age, (1) 29 females and a single stallion (n=30), (2) young females, 1 – 3 years old (n=10) and (3) young of both sexes under 1 year old (n=14). The RBC count, RDW value, Lymp, and Mono counts, and PDW values were statistically greater in donkeys under one year old than in adult donkeys, while the Seg Neu count was lower. The CPK, ALP, iPhos, and HCO3, values were statistically higher in the group of donkeys under 1 year of age than adult donkeys while Cl and LDH values were statistically lower in donkeys under 1 year than adult donkeys. Additionally, statistically significant increased values for CPK, ALP, Alb, Chol, iPhos, HCO3, and UIBC in young donkeys under 1 year when compared with young donkeys, 1 – 3 years were observed. A statistically significant decreased value for Urea and an increased value for Crea in young donkeys, 1 – 3 years old were found as compared to adults. The serum protein fractions recognised by electrophoresis were: albumin, alpha globulin (subdivided into alpha-1 and alpha-2-globulins), beta globulin, and gamma globulin. In the alpha-1-globulin region three small peaks were constantly noticed, and alpha-2-globulins were statistically different between the three groups being greater in young donkeys under 1 year of age. The results obtained were used both to establish reference ranges and a data bank for the farm of Ragusana donkeys for future needs in assessing the metabolic status and health of the animals. 相似文献
3.
Jordi Aleu Mireia Martín-Satué Piedad Navarro Ivanna Pérez de Lara Laia Bahima Jordi Marsal Carles Solsona 《The Journal of physiology》2003,547(1):209-219
ATP mediates intercellular communication. Mechanical stress and changes in cell volume induce ATP release from various cell types, both secretory and non-secretory. In the present study, we stressed Xenopus oocytes with a hypertonic solution enriched in mannitol (300 m m ). We measured simultaneously ATP release and ionic currents from a single oocyte. A decrease in cell volume, the activation of an inward current and ATP release were coincident. We found two components of ATP release: the first was associated with granule or vesicle exocytosis, because it was inhibited by tetanus neurotoxin, and the second was related to the inward current. A single exponential described the correlation between ATP release and the hypertonic-activated current. Gadolinium ions, which block mechanically activated ionic channels, inhibited the ATP release and the inward current but did not affect the decrease in volume. Oocytes expressing CFTR (cystic fibrosis transmembrane regulator) released ATP under hypertonic shock, but ATP release was significantly inhibited in the first component: that related to granule exocytosis. Since the ATP measured is the balance between ATP release and ATP degradation by ecto-enzymes, we measured the nucleoside triphosphate diphosphohydrolase (NTPDase) activity of the oocyte surface during osmotic stress, as the calcium-dependent hydrolysis of ATP, which was inhibited by more than 50 % in hypertonic conditions. The best-characterized membrane protein showing NTPDase activity is CD39. Oocytes injected with an antisense oligonucleotide complementary to CD39 mRNA released less ATP and showed a lower amplitude in the inward current than those oocytes injected with water. 相似文献
4.
Weimer J Shivakumar S Danda S Thomas N Ralui LP Jonat W Arnold N 《Fertility and sterility》2007,88(6):1677.e9-1677.e13
5.
6.
7.
8.
Briones-Buixassa Laia Alí Ítalo Schmidt Carlos Nicolaou Stella Pascual Juan Carlos Soler Joaquim Vega Daniel 《The Psychiatric quarterly》2021,92(3):1035-1054
Psychiatric Quarterly - Non-suicidal self-injury (NSSI) is an increasingly prevalent phenomenon associated with many detrimental outcomes, ranging from poor academic performance to suicide... 相似文献
9.
Maria Carmona-Iragui Daniel Alcolea Isabel Barroeta Laura Videla Laia Muñoz Kathyrn L Van Pelt Frederick A Schmitt Donita D Lightner Lisa M Koehl Gregory Jicha Silvia Sacco Clotilde Mircher Sarah E Pape Rosalyn Hithersay Isabel C H Clare Anthony J Holland Georg Nübling Johannes Levin Juan Fortea 《Lancet neurology》2021,20(8):605-614
10.