全文获取类型
收费全文 | 14990篇 |
免费 | 779篇 |
国内免费 | 228篇 |
专业分类
耳鼻咽喉 | 214篇 |
儿科学 | 128篇 |
妇产科学 | 234篇 |
基础医学 | 2346篇 |
口腔科学 | 190篇 |
临床医学 | 1050篇 |
内科学 | 3190篇 |
皮肤病学 | 479篇 |
神经病学 | 1006篇 |
特种医学 | 1106篇 |
外科学 | 2204篇 |
综合类 | 33篇 |
一般理论 | 2篇 |
预防医学 | 342篇 |
眼科学 | 340篇 |
药学 | 1493篇 |
中国医学 | 204篇 |
肿瘤学 | 1436篇 |
出版年
2024年 | 8篇 |
2023年 | 118篇 |
2022年 | 331篇 |
2021年 | 525篇 |
2020年 | 246篇 |
2019年 | 390篇 |
2018年 | 417篇 |
2017年 | 354篇 |
2016年 | 557篇 |
2015年 | 751篇 |
2014年 | 851篇 |
2013年 | 928篇 |
2012年 | 1447篇 |
2011年 | 1375篇 |
2010年 | 932篇 |
2009年 | 756篇 |
2008年 | 947篇 |
2007年 | 892篇 |
2006年 | 782篇 |
2005年 | 716篇 |
2004年 | 582篇 |
2003年 | 492篇 |
2002年 | 410篇 |
2001年 | 178篇 |
2000年 | 174篇 |
1999年 | 136篇 |
1998年 | 80篇 |
1997年 | 63篇 |
1996年 | 43篇 |
1995年 | 47篇 |
1994年 | 24篇 |
1993年 | 26篇 |
1992年 | 47篇 |
1991年 | 42篇 |
1990年 | 41篇 |
1989年 | 34篇 |
1988年 | 31篇 |
1987年 | 30篇 |
1986年 | 21篇 |
1985年 | 25篇 |
1984年 | 18篇 |
1983年 | 15篇 |
1981年 | 11篇 |
1980年 | 11篇 |
1979年 | 10篇 |
1978年 | 8篇 |
1973年 | 9篇 |
1971年 | 10篇 |
1969年 | 7篇 |
1968年 | 7篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Hyung Jee Kim Gilho Lee Dong Hee Kim Suk Jae Lee Duck Ki Yoon Jae Heung Cho 《Urologia internationalis》2002,68(1):44-48
INTRODUCTION: The purpose of this study is to investigate in vitro the effects of serotonin on the rat detrusor. In particular, it examines which drugs inhibit the serotonin-induced detrusor contractions. MATERIALS AND METHODS: Isometric tension changes of isolated rat bladder muscle strips were recorded in an organ bath using a force transducer. Acute effects of serotonin (0.0001-0.01 mM) on resting tension were assessed. Electrical field stimulation (EFS); bethanechol (0.0001-0.01 mM); ATP (1-3 mM)- or KCl (63.5-254 mM)-induced contractions using an application in an organ bath were compared with serotonin-induced contractions. In order to examine the action mechanism of serotonin-induced stimulation, EFS-, bethanechol-, ATP- or KCl-induced contraction on serotonin treatment (0.001 mM) was assessed and serotonin (0.001-0.1 mM) was cumulatively added to the organ bath following preincubation with propranolol, ketanserin, tropisetron, propiverine, sodium nitroprusside or doxazosin. RESULTS: The serotonin-induced response has two phases: an initial transient contraction and a prolonged tonic phase. Serotonin produced a reversible and dose-dependent contraction of the detrusor strips. Responses to bethanechol significantly increased with a concentration of 0.001 mM serotonin (p < 0.05). There was no effect on the responses to ATP, KCl, or EFS on 0.001 mM serotonin. The 5-HT(2) receptor is mainly responsible for serotonin-induced contractions of the detrusor (p < 0.05), while the 5-HT(1) receptor is partially responsible. Doxazosin and propiverine each significantly suppressed the response to serotonin, while sodium nitroprusside and tropisetron each had no effect (p < 0.05). CONCLUSIONS: Because the 5-HT(2) antagonist blocked the effect of serotonin-induced bladder contractions and the stimulation of the adrenoreceptors, the 5-HT(2) antagonist seems to improve lower urinary tract symptoms. 相似文献
2.
3.
4.
5.
Eun Young Jung Hyung Joo Suh Wan Soo Hong Dong Geon Kim Yang Hee Hong In Sun Hong Un Jae Chang 《Nutrition Research》2009,29(7):457-461
Cooking processes that gelatinize granules or disrupt structure might increase the glucose and insulin responses because a disruption of the structure of starch by gelatinization increases its availability for digestion and absorption in the small intestine. We hypothesized that the uncooked form of rice, which has a relatively low degree of gelatinization even though in powder form, would result in lower metabolic glucose and insulin responses compared with cooked rice (CR). To assess the effects of the gelatinization of rice on metabolic response of glucose and insulin, we investigated the glucose and insulin responses to 3 rice meals of different gelatinization degree in female college students (n = 12): CR (76.9% gelatinized), uncooked rice powder (UP; 3.5% gelatinized), and uncooked freeze-dried rice powder (UFP; 5.4% gelatinized). Uncooked rice powders (UP and UFP) induced lower glucose and insulin responses compared with CR. The relatively low gelatinization degree of UPs resulted in low metabolic responses in terms of the glycemic index (CR: 72.4% vs UP: 49.7%, UFP: 59.8%) and insulin index (CR: 94.8% vs UP: 74.4%, UFP: 68.0%). In summary, UPs that were less gelatinized than CR induced low postprandial glucose and insulin responses. 相似文献
6.
7.
8.
9.
Chang Hyun Lee Jung-Gi Im Jin Mo Goo Hyun Ju Lee Sung-Tae Hong Cheng Hua Shen Doo Hyun Chung Kyu Ri Son Jung Min Chang Hong Eo 《Korean journal of radiology》2007,8(5):372-381
OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. RESULTS: The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. CONCLUSION: The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus. 相似文献
10.
Ischemic necrosis of the entire femoral head and rapidly destructive hip disease: potential causative relationship 总被引:6,自引:0,他引:6
Kyung Nam Ryu Eui Jong Kim Myung Chul Yoo Yong Koo Park David J. Sartoris Donald Resnick 《Skeletal radiology》1997,26(3):143-149
Objective. Rapidly destructive hip disease (RDHD) is an uncommon disorder of the hip that has been considered a disease of unknown cause
and distinct from ischemic necrosis of the femoral head. The objective of this study was to investigate ischemic necrosis
of the femoral head as one potential cause of RDHD. Design and patients. In 600 patients who underwent MR imaging of the hip, 20 cases of ischemic necrosis involving the entire femoral head in 18
patients (3%) were retrospectively studied with routine radiography and MR imaging. All patients had surgically confirmed
ischemic necrosis of the femoral head. Results and conclusions. All patients showed rapid destruction of the femoral head on routine radiography and MR imaging as compared with the gradual
onset of clinical symptoms. Plain radiographs showed several bone fragments at the inferomedial aspect of the femoral head
(75%), acetabular erosions (55%), eccentric depression at the lateral articular surface of the femoral head conforming to
the adjacent acetabulum (35%), and mild osteoarthritis (15%). Bone sclerosis was often present at sites of impaction between
the femoral head and the acetabulum. MR imaging showed marked distention of the joint capsule in all cases. In 14 of 20 cases,
the contents of the joint space showed predominantly low or intermediate signal intensity on T1- and T2-weighted images. Ischemic
necrosis involving the entire femoral head may represent one of the causes of RDHD. 相似文献