全文获取类型
收费全文 | 6046篇 |
免费 | 342篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 63篇 |
儿科学 | 164篇 |
妇产科学 | 93篇 |
基础医学 | 933篇 |
口腔科学 | 140篇 |
临床医学 | 394篇 |
内科学 | 1583篇 |
皮肤病学 | 122篇 |
神经病学 | 650篇 |
特种医学 | 110篇 |
外科学 | 584篇 |
综合类 | 33篇 |
一般理论 | 1篇 |
预防医学 | 204篇 |
眼科学 | 216篇 |
药学 | 575篇 |
中国医学 | 35篇 |
肿瘤学 | 509篇 |
出版年
2023年 | 49篇 |
2022年 | 68篇 |
2021年 | 149篇 |
2020年 | 63篇 |
2019年 | 115篇 |
2018年 | 136篇 |
2017年 | 91篇 |
2016年 | 128篇 |
2015年 | 133篇 |
2014年 | 162篇 |
2013年 | 197篇 |
2012年 | 335篇 |
2011年 | 385篇 |
2010年 | 215篇 |
2009年 | 183篇 |
2008年 | 345篇 |
2007年 | 392篇 |
2006年 | 351篇 |
2005年 | 382篇 |
2004年 | 341篇 |
2003年 | 334篇 |
2002年 | 331篇 |
2001年 | 97篇 |
2000年 | 120篇 |
1999年 | 116篇 |
1998年 | 56篇 |
1997年 | 50篇 |
1996年 | 46篇 |
1995年 | 34篇 |
1994年 | 49篇 |
1993年 | 32篇 |
1992年 | 105篇 |
1991年 | 74篇 |
1990年 | 83篇 |
1989年 | 75篇 |
1988年 | 62篇 |
1987年 | 73篇 |
1986年 | 68篇 |
1985年 | 50篇 |
1984年 | 38篇 |
1983年 | 35篇 |
1982年 | 35篇 |
1981年 | 23篇 |
1980年 | 15篇 |
1979年 | 25篇 |
1978年 | 16篇 |
1974年 | 14篇 |
1973年 | 19篇 |
1968年 | 13篇 |
1967年 | 13篇 |
排序方式: 共有6409条查询结果,搜索用时 31 毫秒
1.
Hori Hiroki Ohta Asuka Matsui Honami Yano Kanako Morita-Tominaka Miyuki Linn Zayar Masumoto Daisuke Okumura Yosuke Okamura Satoshi Kurihara Kosuke Hayakawa Akira Rikiishi Takeshi Kobayashi Kyoko 《International journal of clinical oncology / Japan Society of Clinical Oncology》2022,27(1):245-252
International Journal of Clinical Oncology - The practice of cancer diagnosis disclosure to children has been changed with the times. The regulations of clinical trials in the 2000s might change... 相似文献
2.
3.
4.
5.
Hiroto Kinoshita Hitomi Nishioka Aya Ikeda Kyoko Ikoma Yoichi Sameshima Hidehisa Ohi Mizuki Tatsuno Junka Kouyama Chiaki Kawamoto Tomohiro Mitsui Yuko Tamura Yu Hashimoto Masashi Nishio Tsuyoshi Ogashiwa Yusuke Saigusa Shin Maeda Hideaki Kimura Reiko Kunisaki Kazuhiko Koike 《Journal of gastroenterology and hepatology》2019,34(11):1929-1939
6.
7.
Hidetaro Mori Keisuke Hiraoka Ryoichi Yorifuji Tohru Iwasaki Syuzo Gomikawa Ohshi Inagaki Seishi Inoue Yoshihiro Takamitsu Yoshikazu Fujita 《Artificial organs》1994,18(10):725-728
Abstract: The adsorptive characteristics of 5 dialysis membranes for recombinant human erythropoietin (EPO) were studied in vitro in a closed circuit system. For 120 min, EPO added with bovine serum was significantly adsorbed by polymethylmetacrylate (PMMA) and polyacry–lonitrile (PAN) membranes but not by Cuprophan, ethylene vinyl alcohol (EVAL), or polysulfone (PS) membranes. In addition the EPO adsorptive rate, as well as that of β2 –microglobulin (β2 –MG), was greater with a PMMA membrane than with a PAN membrane. EPO was not detected in the ultrafiltrate at 15 min with 5 membranes. These results indicate that EPO was eliminated by membrane adsorption only with some dialysis membranes. 相似文献
8.
9.
K Tamazawa H Arima T Kojima Y Isomura M Okada S Fujita T Furuya T Takenaka O Inagaki M Terai 《Journal of medicinal chemistry》1986,29(12):2504-2511
Four enantiomers (3a-d) of the title compound, YM-09730 (3), were synthesized by the reaction of (-)- or (+)-5-(methoxycarbonyl)-2, 6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid (1a or 1b) with (S)- or (R)-1-benzyl-3-pyrrolidinol (2a or 2b). [3H]Nitrendipine binding affinity and coronary vasodilating activity of these compounds were evaluated. The absolute configuration of the most potent enantiomer (3a) with the longest duration was unequivocally determined to be (S)-1,4-dihydropyridine-C4 and (S)-pyrrolidine-C3 (S,S) by X-ray crystallographic study on 3a X HBr as well as 3a X HCl. The configuration of 1a corresponds to R, and the other enantiomers of 3 were respectively determined by chemical correlation. The potency order of the four enantiomers was (S,S)-3a greater than (S,R)-3b greater than (R,R)-3d greater than (R,S)-3c. Latent chiral characters of nifedipine derivatives with the identical ester groups were assigned by comparison of their puckering modes of 1,4-dihydropyridine (DHP) rings with those found in 3a X HCl or 3a X HBr. On the basis of the assignment, it has been revealed that the (S)-DHP nifedipine derivatives possess the synperiplanar carbonyl group at C5. The conformational restriction may be a factor causing stereoselectivity of antagonism. 相似文献
10.