全文获取类型
收费全文 | 182篇 |
免费 | 1篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 13篇 |
妇产科学 | 2篇 |
基础医学 | 41篇 |
口腔科学 | 2篇 |
临床医学 | 38篇 |
内科学 | 9篇 |
皮肤病学 | 1篇 |
神经病学 | 19篇 |
外科学 | 1篇 |
预防医学 | 22篇 |
眼科学 | 6篇 |
药学 | 26篇 |
肿瘤学 | 2篇 |
出版年
2020年 | 1篇 |
2019年 | 3篇 |
2018年 | 2篇 |
2016年 | 4篇 |
2015年 | 1篇 |
2014年 | 2篇 |
2013年 | 3篇 |
2012年 | 3篇 |
2011年 | 4篇 |
2010年 | 4篇 |
2009年 | 4篇 |
2008年 | 5篇 |
2007年 | 7篇 |
2006年 | 4篇 |
2005年 | 4篇 |
2004年 | 3篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 10篇 |
2000年 | 6篇 |
1999年 | 6篇 |
1998年 | 3篇 |
1996年 | 3篇 |
1994年 | 1篇 |
1992年 | 4篇 |
1991年 | 7篇 |
1990年 | 7篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 5篇 |
1986年 | 7篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1983年 | 6篇 |
1982年 | 3篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1978年 | 4篇 |
1977年 | 2篇 |
1976年 | 3篇 |
1975年 | 6篇 |
1974年 | 4篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1971年 | 4篇 |
1970年 | 1篇 |
1969年 | 4篇 |
1968年 | 2篇 |
1967年 | 3篇 |
1966年 | 4篇 |
排序方式: 共有183条查询结果,搜索用时 15 毫秒
1.
Pulina N. A. Kuznetsov A. S. Krasnova A. I. Novikova V. V. 《Pharmaceutical Chemistry Journal》2019,53(3):220-224
Pharmaceutical Chemistry Journal - N-Substituted 4-aryl-2-hydroxy-4-oxobut-2-enoic acid hydrazides and their complexes with Ni(II), Mn(II), Co(II), Cu(II), and Zn(II) were prepared. Their... 相似文献
2.
T. N. Krasnova I. P. Kryukova A. E. Krasnov V. G. Lebedev L. A. Pankova 《Biomedical engineering》1998,32(3):140-147
Conclusion The method of diagnosis of diseases based on the syndrome analysis is generally acknowledged. It should be noted that the
methods described in this work formalize such important concepts as symptom, symptom-complex, simple and complicated syndromes,
degrees of their manifestation and certainty, and their diagnostic value. The diagnostic algorithms developed on the basis
of these concepts save the physician a great deal of routine work (studying results of numerous analyses and examinations)
and provide consultative aid. Syndrome diagnosis of renal diseases has been considered as an example.
Diagnostic systems using the method of early diagnosis of diseases described in this work will provide improved quality and
reliability of diagnosis because monitoring of pathological deviations is performed automatically. The physician is immediately
informed about revealed pathological deviations, symptoms, and syndromes; exacerbation of chronic diseases and appearance
of new diseases. The automated system makes card catalogs unnecessary, being more expedient. Also, the automated system provides
necessary reference information.
Sechenov Moscow Medical Academy. Institute for Problems of Management, Russian Academy of Sciences, Moscow. Translated from
Meditsinskaya Tekhnika, No. 3, pp. 20–26, May–June, 1998. 相似文献
3.
4.
Irina N Krasnova Nathan J Marchant Bruce Ladenheim Michael T McCoy Leigh V Panlilio Jennifer M Bossert Yavin Shaham Jean L Cadet 《Neuropsychopharmacology》2014,39(8):2008-2016
In a rat model of drug craving and relapse, cue-induced drug seeking progressively increases after withdrawal from methamphetamine and other drugs, a phenomenon termed ‘incubation of drug craving''. However, current experimental procedures used to study incubation of drug craving do not incorporate negative consequences of drug use, which is a common factor promoting abstinence in humans. Here, we studied whether incubation of methamphetamine craving is observed after suppression of drug seeking by adverse consequences (punishment). We trained rats to self-administer methamphetamine or palatable food for 9 h per day for 14 days; reward delivery was paired with a tone-light cue. Subsequently, for one group within each reward type, 50% of the lever-presses were punished by mild footshock for 9–10 days, whereas for the other group lever-presses were not punished. Shock intensity was gradually increased over time. Next, we assessed cue-induced reward seeking in 1-h extinction sessions on withdrawal days 2 and 21. Response-contingent punishment suppressed extended-access methamphetamine or food self-administration; surprisingly, food-trained rats showed greater resistance to punishment than methamphetamine-trained rats. During the relapse tests, both punished and unpunished methamphetamine- and food-trained rats showed significantly higher cue-induced reward seeking on withdrawal day 21 than on day 2. These results demonstrate that incubation of both methamphetamine and food craving occur after punishment-induced suppression of methamphetamine or palatable food self-administration. Our procedure can be used to investigate mechanisms of relapse to drug and palatable food seeking under conditions that more closely approximate the human condition. 相似文献
5.
Zubareva OE Krasnova IN Abdurasulova IN Bluthe RM Dantzer R Klimenko VM 《Brain research》2001,915(2):244-247
The ability of the brain serotonergic system to mediate the effects of interleukin-1beta (IL-1beta) was investigated. Intracerebroventricular administration of IL-1beta induced a significant pyrogenic reaction, depression in social behaviour, loss of body weight and reduced food intake in rats. Pre-treatment with p-chlorphenylalanine, an inhibitor of serotonin synthesis, blocked the IL-1beta-induced decrease in food intake and loss of body weight, but failed to alter the temperature increase and the decrease in communicative activity. 相似文献
6.
7.
8.
9.
10.
Shilov EM Tareeva IE Ivanov AA Lavrova ON Krasnova TN Khudova IIu Miroshnichenko NG Ratner MIa Biriukova LS 《Terapevticheski? arkhiv》2000,72(6):21-25
AIM: To retrospectively analyze clinical course and results of immunodepressive therapy of patients with primary focal-segmental glomerulosclerosis (FSGS), to reveal prognostic factors of the disease progression and patients' sensitivity to immunosuppressive therapy. MATERIAL AND METHODS: Morphological diagnosis was specified, morphological indices of activity and sclerosis were estimated, renal survival was analysed, mono- and multivariate analysis of prognostic factors was made by the evidence obtained in the study of 135 biopsy specimens from CRF patients meeting the criteria of FSGS. RESULTS: At the moment of the disease onset only age of the patients was related to FSGS: 5- and 10-year survival was 100% if the disease started under 16 years of age, if older--the survival was 80 and 65%, respectively. Nephrotic syndrome, hematuria, high creatinine, racemose alterations in the glomeruli worsened the disease prognosis. When cytostatics and corticosteroids were used in combination they produced better results and were associated with better prognosis than each of them in monotherapy. Patients with marked hematuria and low proteinuria were less sensitive to therapy than those with weak hematuria and high proteinemia. Patients with FSGS having high IA and SI required more aggressive therapy for response. CONCLUSION: Renal biopsy with quantitation of IA and IS increases the prognosis accuracy and is important for choice of the treatment policy in patients with primary FSGS. 相似文献