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排序方式: 共有54条查询结果,搜索用时 31 毫秒
1.
Ghosh K Mukherjee MB Shankar U Kote SL Nagtilak SB Kolah RB Surve RR Tamankar AA Sukumar S Mohanty 《Indian journal of public health》2002,46(2):61-65
In a boarding school of Maharashtra State of India 314 students (Bhil & Pawar) were examined clinically and blood was examined. Anemia was present in 16.2% male & 38.3% female. B (Beta). Thalasemia trait was present in 1.6% male & 2.4% female. Sickle cell trait was present in 21.3% male and 14.4% female and sickle cell disease in 0.6% student. G6PD deficiency was seen in 5.1% male & 4.8% female students. 相似文献
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Mark L. Eberhard Gholamabbas Amin Ostovar Kote Chundu Dan Hobohm Iman Feiz-Erfan Blaine A. Mathison Henry S. Bishop Paul T. Cantey 《The American journal of tropical medicine and hygiene》2013,88(3):601-605
A 22-month-old girl presented with neck pain and stiffness and magnetic resonance imaging showed an extradural mass extending from C2 through the C4 level with moderate to severe compression of the cord. A left unilateral C2–C4 laminectomy was performed revealing an extradural rubbery tumor; a small biopsy was obtained. Examination of stained tissue revealed the presence of a parasitic worm that was identified as a gravid female Onchocerca lupi. A magnetic resonance imaging at 7 weeks follow-up showed a significantly decreased size of the enhancing lesion and the patient''s symptoms gradually resolved. This is the first report of zoonotic O. lupi in the United States. The parasite has been reported in dogs and cats in the western United States, and from people in four cases reported from Europe. A great deal more needs to be learned, including full host range and geographic distribution, before we fully understand O. lupi infections in animals and man. 相似文献
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The effects of different monochromatic light colors (wavelengths) on the feeding pattern and predatory efficiency of Gambusia affinis have been studied. Maximum predation of mosquito larvae by the fish is observed under red illumination (680 mμ). The different light colors do not alter the feeding pattern of the fish but markedly influence the predatory efficiency of the fish. 相似文献
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Chichinadze K 《Neuroscience and behavioral physiology》2005,35(1):1-3
Neuroscience and Behavioral Physiology - 相似文献
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gsSKAT: Rapid gene set analysis and multiple testing correction for rare‐variant association studies using weighted linear kernels
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Nicholas B. Larson Shannon McDonnell Lisa Cannon Albright Craig Teerlink Janet Stanford Elaine A. Ostrander William B. Isaacs Jianfeng Xu Kathleen A. Cooney Ethan Lange Johanna Schleutker John D. Carpten Isaac Powell Joan E. Bailey‐Wilson Olivier Cussenot Geraldine Cancel‐Tassin Graham G. Giles Robert J. MacInnis Christiane Maier Alice S. Whittemore Chih‐Lin Hsieh Fredrik Wiklund William J. Catolona William Foulkes Diptasri Mandal Rosalind Eeles Zsofia Kote‐Jarai Michael J. Ackerman Timothy M. Olson Christopher J. Klein Stephen N. Thibodeau Daniel J. Schaid 《Genetic epidemiology》2017,41(4):297-308
Next‐generation sequencing technologies have afforded unprecedented characterization of low‐frequency and rare genetic variation. Due to low power for single‐variant testing, aggregative methods are commonly used to combine observed rare variation within a single gene. Causal variation may also aggregate across multiple genes within relevant biomolecular pathways. Kernel‐machine regression and adaptive testing methods for aggregative rare‐variant association testing have been demonstrated to be powerful approaches for pathway‐level analysis, although these methods tend to be computationally intensive at high‐variant dimensionality and require access to complete data. An additional analytical issue in scans of large pathway definition sets is multiple testing correction. Gene set definitions may exhibit substantial genic overlap, and the impact of the resultant correlation in test statistics on Type I error rate control for large agnostic gene set scans has not been fully explored. Herein, we first outline a statistical strategy for aggregative rare‐variant analysis using component gene‐level linear kernel score test summary statistics as well as derive simple estimators of the effective number of tests for family‐wise error rate control. We then conduct extensive simulation studies to characterize the behavior of our approach relative to direct application of kernel and adaptive methods under a variety of conditions. We also apply our method to two case‐control studies, respectively, evaluating rare variation in hereditary prostate cancer and schizophrenia. Finally, we provide open‐source R code for public use to facilitate easy application of our methods to existing rare‐variant analysis results. 相似文献
7.
Teimuraz Lezhava Jamlet Monaselidze Tina Jokhadze Nona Kakauridze Nodar Khodeli Mamanti Rogava Tamara Bochorishvili Maia Gorgoshidze Dato Khachidze Eteri Lomidze Jaba Tkemaladze Kote Chichinadze Marina Koridze Rusudan Khukhuneishvili Nato Zosidze Marina Nagervadze Tamara Buadze Maia Gaiozishvili 《Biogerontology》2011,12(2):87-91
Gerontology research carried out in different scientific centers of Georgia follows the basic directions of most work in this field: epidemiology, investigation of the mechanisms of aging, and finding ways to prevent senile pathologies and to prolong life. The genealogy and epidemiology of long-living peaple have been studied in areas with high occurrence of these people by considering the sex ratio and social status of the long-living, the influence of environmental factors, and the development of senile pathologies. According to the centrosome (centriole) model of aging, the centrosomes and the cytoskeleton, important structures in cellular differentiation and morphogenesis, may be involved in the initiation of the replication senescence mechanism. Our analysis of genetic studies shows that progressive chromosome heterochromatinization (condensation of eu- and heterochromatin regions) occurs in aging. Decreases in the repair processes and increases in the frequency of chromosome aberrations during aging are secondary to this progressive chromosome heterochromatinization. Chromosome heterochromatinization is a key factor in aging but may be reversible under the influence of bioregulators, some chemical substances, and heavy metal salts. The study of chromosome heterochromatinization may provide clues to the potential for prolonging the human lifespan. 相似文献
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Induction of erythroid differentiation and modulation of gene expression by tiazofurin in K-562 leukemia cells. 总被引:2,自引:0,他引:2
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