全文获取类型
收费全文 | 4320篇 |
免费 | 185篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 67篇 |
妇产科学 | 16篇 |
基础医学 | 484篇 |
口腔科学 | 94篇 |
临床医学 | 253篇 |
内科学 | 1082篇 |
皮肤病学 | 265篇 |
神经病学 | 363篇 |
特种医学 | 129篇 |
外科学 | 838篇 |
综合类 | 9篇 |
预防医学 | 153篇 |
眼科学 | 22篇 |
药学 | 322篇 |
中国医学 | 11篇 |
肿瘤学 | 400篇 |
出版年
2023年 | 24篇 |
2022年 | 31篇 |
2021年 | 68篇 |
2020年 | 30篇 |
2019年 | 35篇 |
2018年 | 96篇 |
2017年 | 77篇 |
2016年 | 82篇 |
2015年 | 81篇 |
2014年 | 110篇 |
2013年 | 147篇 |
2012年 | 216篇 |
2011年 | 235篇 |
2010年 | 134篇 |
2009年 | 129篇 |
2008年 | 193篇 |
2007年 | 228篇 |
2006年 | 258篇 |
2005年 | 226篇 |
2004年 | 234篇 |
2003年 | 243篇 |
2002年 | 239篇 |
2001年 | 102篇 |
2000年 | 115篇 |
1999年 | 137篇 |
1998年 | 94篇 |
1997年 | 59篇 |
1996年 | 63篇 |
1995年 | 30篇 |
1994年 | 30篇 |
1993年 | 34篇 |
1992年 | 83篇 |
1991年 | 82篇 |
1990年 | 70篇 |
1989年 | 77篇 |
1988年 | 56篇 |
1987年 | 38篇 |
1986年 | 33篇 |
1985年 | 39篇 |
1984年 | 30篇 |
1983年 | 24篇 |
1982年 | 12篇 |
1979年 | 25篇 |
1978年 | 20篇 |
1977年 | 20篇 |
1975年 | 13篇 |
1974年 | 11篇 |
1972年 | 14篇 |
1970年 | 13篇 |
1968年 | 9篇 |
排序方式: 共有4520条查询结果,搜索用时 12 毫秒
1.
2.
3.
Koji Saito Takashi Saito Sumio Kawada 《Nihon Shokakibyo Gakkai zasshi》2006,103(10):1176, 1179-1176, 1180
4.
5.
6.
Acute Immobilization Stress and Intraventricular Injection of CRF Suppress Naloxone-Induced LH Release in Ovariectomized Estrogen-Primed Rats 总被引:1,自引:0,他引:1
Tatsuo Akema Atsuhiko Chiba Reiji Shinozaki Morihiro Oshida Fukuko Kimura & Jun-ichi Toyoda 《Journal of neuroendocrinology》1996,8(8):647-652
The present study was undertaken to evaluate the role and possible interaction of the endogenous opioid peptide (EOP) and corticotropin-releasing factor (CRF) in the acute stress-induced suppression of gonadotropin secretion in ovariectomized estrogen-primed rats. An intravenous (i.v.) injection of naloxone (10 or 20 mg/kg), an EOP antagonist, significantly elevated serum luteinizing hormone (LH) levels within 10 min in non-stressed animals. The naloxone-induced LH release was completely eliminated when tested 30 min after the onset of acute immobilization. In a subsequent study, it was found that suppression of the naloxone-induced LH release occurred as early as 5 min after the stress onset, and was still evident 60 min after the end of a 30-min period of immobilization. The effect of naloxone was restored 3 h after liberation of the animal from the 30-min immobilization. An intraventricular (i.c.v.) injection of CRF (1 or 5 μg) also significantly suppressed, in a dose-related manner, the effect of a subsequent i.v. injection of naloxone. However, an i.c.v. injection of α -helical CRF(9-41) (25 or 50 μg), a CRF antagonist, prior to immobilization, could not interfere with the suppressive effect of stress on naloxone-induced LH release. These results suggest that both acute immobilization stress and CRF can inhibit the LH secretory activity without mediation by EOP neurons. However, the stress-related suppression may involve non-CRF mechanism(s). 相似文献
7.
Toshiaki Otsuka Tomoyuki Kawada Masao Katsumata Chikao Ibuki Yoshiki Kusama 《Hypertension research》2007,30(12):1211-1218
The second derivative of the finger photoplethysmogram (SDPTG) has been used as a non-invasive examination for arterial stiffness. The present study sought to elucidate independent determinants of the SDPTG among various cardiovascular risk factors in middle-aged Japanese men. The SDPTG was obtained from the cuticle of the left-hand forefinger in 973 male workers (mean age: 44+/-6 years) during a medical checkup at a company. The SDPTG indices (b/a and d/a) were calculated from the height of the wave components. Multiple logistic regression analyses revealed that the independent determinants of an increased b/a (highest quartile of the b/a) were age (odds ratio [OR]: 1.12 per 1-year increase, 95% confidence interval [CI]: 1.09-1.15), hypertension (OR: 1.65, 95% CI: 1.03-2.65), dyslipidemia (OR: 1.51, 95% CI: 1.09-2.09), impaired fasting glucose/diabetes mellitus (OR: 2.43, 95% CI: 1.16-5.07), and a lack of regular exercise (OR: 2.00, 95% CI: 1.29-3.08). Similarly, independent determinants of a decreased d/a (lowest quartile of the d/a) were age (OR: 1.11 per 1-year increase, 95% CI: 1.08-1.14), hypertension (OR: 3.44, 95% CI: 2.20-5.38), and alcohol intake 6 or 7 days per week (OR: 2.70, 95% CI: 1.80-4.06). No independent association was observed between the SDPTG indices and blood leukocyte count or serum C-reactive protein levels. In conclusion, the SDPTG indices reflect arterial properties affected by several cardiovascular risk factors in middle-aged Japanese men. The association between inflammation and the SDPTG should be evaluated in further studies. 相似文献
8.
This paper describes a new class of reaction, group-transfer alternating copolymerization (GTAC), between 2-phenyl-1,3,2-dioxaphosphorinane ( 1 ) and trimethylsilyl 2-(acryloyloxy)ethanesulfonate ( 2 ). The copolymerization took place without any added catalyst and proceeded via quantitative trimethylsilyl group-transfer process to give a 1:1 alternating copolymer 3a having a ketene silyl acetal group in the main chain. Results of spectroscopy as well as alkaline hydrolysis and bromination of the copolymer confirmed the structure. 相似文献
9.
M Arai H Kawada T Kaburagi N Sakai Y Kudou M Kawakami K Konno T Takizawa 《Nihon Kyōbu Shikkan Gakkai zasshi》1991,29(11):1457-1463
A 40-year-old man who lived in a wooden house built 30 years ago presented with complaints of fever, dry cough and dyspnea. Chest X-ray findings showed interstitial shadows throughout bilateral lung fields. After admission, high-dose administration of 3000 mg of methylprednisolone was performed because of deterioration of chest X-ray shadows and symptoms. In a week, clinical data and symptoms improved. Findings of BAL fluid on admission revealed a relative increase of lymphocytes, neutrophils and mast cells, and pathological findings of transbronchial lung biopsy revealed non-caseous granulation and alveolitis. Precipitating antibodies and indirect fluorescent antibodies against Trichosporon cutaneum and Cryptococcus neoformans had positive reactions and T. cutaneum was isolated and identified from the patient's house. A diagnosis of summer-type hypersensitivity pneumonitis was made according to the criteria advocated by Ando et al. This seemed to be a rare case of summer-type hypersensitivity pneumonitis prolonged after isolation from his normal living environment, successfully treated by high-dose administration of steroid. 相似文献
10.
A 28-year-old woman developed numbness and weakness of the hands and arms when she was 8 months pregnant, and weakness worsened gradually. However, weakness started to spontaneously subside immediately after delivery and she felt almost recovered several hours later. But weakness and numbness recurred one week after delivery and she was admitted to our hospital. Neurological examination revealed moderate weakness and disturbance of the deep and cutaneous sensations in the upper and lower extremities, and marked decrease of the deep tendon reflexes. The upper extremities were more severely affected. Nerve conduction study showed marked decrease in the motor conduction velocities. Cerebrospinal fluid showed increase of protein without pleocytosis. Teased preparation of the biopsied sural nerve showed occasional internodal segments with thin myelination, indicating demyelination and remyelination. A diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy was made. Treatment with prednisolone markedly improved the weakness and hyporeflexia as well as the cerebrospinal fluid protein. Postpartum rapid remission may have been produced by rapid increase of endogenous steroid hormone in the blood by its massive excretion during delivery. 相似文献