全文获取类型
收费全文 | 23783篇 |
免费 | 1288篇 |
国内免费 | 83篇 |
专业分类
耳鼻咽喉 | 178篇 |
儿科学 | 695篇 |
妇产科学 | 621篇 |
基础医学 | 2761篇 |
口腔科学 | 420篇 |
临床医学 | 2814篇 |
内科学 | 4902篇 |
皮肤病学 | 375篇 |
神经病学 | 2248篇 |
特种医学 | 429篇 |
外科学 | 2527篇 |
综合类 | 409篇 |
一般理论 | 20篇 |
预防医学 | 3227篇 |
眼科学 | 743篇 |
药学 | 1368篇 |
中国医学 | 35篇 |
肿瘤学 | 1382篇 |
出版年
2023年 | 98篇 |
2022年 | 96篇 |
2021年 | 307篇 |
2020年 | 189篇 |
2019年 | 298篇 |
2018年 | 387篇 |
2017年 | 282篇 |
2016年 | 302篇 |
2015年 | 389篇 |
2014年 | 542篇 |
2013年 | 858篇 |
2012年 | 1602篇 |
2011年 | 1887篇 |
2010年 | 823篇 |
2009年 | 681篇 |
2008年 | 1732篇 |
2007年 | 1828篇 |
2006年 | 1782篇 |
2005年 | 1819篇 |
2004年 | 1753篇 |
2003年 | 1612篇 |
2002年 | 1482篇 |
2001年 | 641篇 |
2000年 | 715篇 |
1999年 | 416篇 |
1998年 | 253篇 |
1997年 | 175篇 |
1996年 | 163篇 |
1995年 | 137篇 |
1994年 | 117篇 |
1993年 | 115篇 |
1992年 | 101篇 |
1991年 | 82篇 |
1990年 | 83篇 |
1989年 | 88篇 |
1988年 | 84篇 |
1987年 | 56篇 |
1986年 | 61篇 |
1985年 | 62篇 |
1984年 | 74篇 |
1983年 | 92篇 |
1982年 | 81篇 |
1981年 | 81篇 |
1980年 | 67篇 |
1979年 | 51篇 |
1978年 | 54篇 |
1977年 | 50篇 |
1976年 | 39篇 |
1974年 | 40篇 |
1973年 | 33篇 |
排序方式: 共有10000条查询结果,搜索用时 10 毫秒
1.
2.
Data on 232 members of a single pedigree, descended from two pairs of original parents, were made available to the participants of Genetic Analysis Workshop 8 (GAW8). In addition to information concerning age and sex, measurements for 10 quantitative traits and genotypes at 22 polymorphic marker loci were also provided for a subset of 193 of these family members. © 1993 Wiley-Liss, Inc. 相似文献
3.
Compromise of immune function in obstructive jaundice. 总被引:5,自引:0,他引:5
4.
Cristina Benatti Silvia Alboni Giacomo Capone Daniela Corsini Federica Caggia Nicoletta Brunello Fabio Tascedda Joan M.C. Blom 《International journal of developmental neuroscience》2009,27(7):661-668
Protracted or recurrent pain and inflammation in the early neonatal period may cause long-lasting changes in central neural function. However, more research is necessary to better characterize the long-term behavioral sequelae of such exposure in the neonatal period. Objectives: (1) to study whether timing of postnatal exposure to persistent inflammation alters responsiveness to thermal pain in the adult animal; (2) to assess whether animals experiencing early postnatal chronic inflammation display altered anxiety related behavior; (3) to study the importance of genetic background. Newborn mice (outbred strain, CD1 and F1 hybrid strain, B6C3F1) received an injection of Complete Freund's Adjuvant (CFA) or saline on either postnatal day 1 or 14 (PND1; PND14) into the left hind paw. Pain to radiant heat and anxiety were examined in 12-week-old adult animals. Adult baseline PWL was significantly decreased in CD1 mice exposed to CFA on PND 1 and 14 as compared to their saline treated counterparts. B6C3F1 mice exposed to CFA on PND14 showed markedly reduced baseline PWL compared to the PND14 saline group. Persistent inflammation experienced by B6C3F1 mice on PND1 failed to affect baseline adult thermal responsiveness. Adult mice, CD1 and B6C3F1, displayed low anxiety traits only if they had been exposed to persistent inflammation on PND1 and not on PND14. Our research suggests a role for genetic background in modulating long-term behavioral consequences of neonatal persistent inflammation: the data support the hypothesis that pain experienced very early in life differentially affects adult behavioral and emotional responsiveness in outbred (CD1) and hybrid mice (B6C3F1). 相似文献
5.
Joan M. Farrell Ida A. Shaw 《Journal of behavior therapy and experimental psychiatry》2009,40(2):317-328
This study tests the effectiveness of adding an eight-month, thirty-session schema-focused therapy (SFT) group to treatment-as-usual (TAU) individual psychotherapy for borderline personality disorder (BPD). Patients (N = 32) were randomly assigned to SFT-TAU and TAU alone. Dropout was 0% SFT, 25% TAU. Significant reductions in BPD symptoms and global severity of psychiatric symptoms, and improved global functioning with large treatment effect sizes were found in the SFT-TAU group. At the end of treatment, 94% of SFT-TAU compared to 16% of TAU no longer met BPD diagnosis criteria (p < .001). This study supports group SFT as an effective treatment for BPD that leads to recovery and improved overall functioning. 相似文献
6.
7.
8.
Gerard J Molloy Derek W Johnston Chuan Gao Miles D Witham Joan M Gray Ishbel S Argo Allan D Struthers Marion E T McMurdo 《European journal of cardiovascular prevention and rehabilitation》2006,13(3):381-387
BACKGROUND: The impact of exercise programmes for heart failure on those close to the patient is largely unknown. We examined the effect of a hospital and home-based exercise intervention on burden, anxiety and depression of informal caregivers. DESIGN: The study was a randomized, controlled trial. Heart failure patients were randomized to a seated 12-week hospital-based exercise programme. Caregiver measures were gathered at baseline, 3 months later and 6 months following baseline. METHODS: Sixty caregivers (mean age 63.4 years, 65% female) of heart failure patients (n = 82, mean age 80.5 years, 44% female) participating in a trial of an exercise intervention were recruited. Caregiver burden, anxiety and depression were assessed. RESULTS: There were no differences in caregiver burden, depression or anxiety between the two groups of caregivers at baseline (caregiver burden, patient control 33.1 versus patient exercise 34.1; anxiety 4.1 versus 5.5; depression 2.8 versus 3.8). At 3 months there were no differences between caregivers in the two groups on outcomes. At 6-month follow-up caregivers of heart failure patients in the exercise group had burden scores that were significantly worse than the control group. There were no differences between the carers of exercise and control groups in anxiety and depression. Levels of anxiety and depression in the entire carer sample were marginally higher than reference values in a healthy non-clinical sample. CONCLUSION: The present exercise interventions for frail older patients did not benefit caregivers and was associated with an increase in caregiver burden. We suggest that future exercise interventions for heart failure patients should actively incorporate informal caregivers into research designs. 相似文献
9.
10.
Levente Gáspár Zoltán Jónás László Kiss György Vereb Zoltán Csernátony 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2009,19(6):403-407
Background Coccygodynia can cause severe pain and disability in patients. There are contradictions in the literature regarding the final
results of coccygectomy for coccygodynia. We evaluated the long-term effects of coccygectomy on the intensity, characteristics,
and manifestation of pain caused by coccygodynia to determine the adequacy of operation among treatment modalities.
Materials and methods Thirty-four patients with coccygodynia were treated by coccygectomy. In 22 cases, trauma, and in one case childbirth was the
cause. 11 cases were regarded as idiopathic. The intensity, characteristics of pain, and the most painful activities were
evaluated at an average of 7.6 (3–18) years of follow-up time.
Results Before the operation, all 34 patients had pain while sitting, moreover, 26 of them had pain during standing, walking, at night
or a combination of these. 21 patients had intolerable or very intensive, mainly acute, sharp or burning pain. 11 patients
had dyschesia, 2 had dysuria and 6 had dyspareunia. At follow-up, 7 patients were completely free of pain, 15 others had moderate,
11 medium, and only one patient had severe, but none had intolerable pain. Only seven patients had acute, sharp or burning
pain postoperatively. The decrease of average pain score from 8.0 to 3.2 was significant (P < 10−12). The number of the patients with dyschesia and dyspareunia decreased from 11 to 7 and from 6 to 3, respectively. Two patients
had dysuria, but their complaints did not change after the operation. One of the two patients who needed reoperation had an
excellent final result, while the other remained unchanged. 12 and 16 patients (together 82%) regarded the final result of
the operation excellent and good, respectively. The condition of five others did not change, while one became worse. The patients
with younger age, smaller body mass index, and less co-morbidities had better final result. There were no serious complications.
Conclusion Coccygectomy for coccygodynia is a safe method to decrease the intensity of pain and other complaints of the patients. The
operation can be the choice of treatment if conservative measures fail. 相似文献