全文获取类型
收费全文 | 56901篇 |
免费 | 4665篇 |
国内免费 | 234篇 |
专业分类
耳鼻咽喉 | 642篇 |
儿科学 | 1560篇 |
妇产科学 | 1102篇 |
基础医学 | 8110篇 |
口腔科学 | 798篇 |
临床医学 | 6140篇 |
内科学 | 12733篇 |
皮肤病学 | 1180篇 |
神经病学 | 6129篇 |
特种医学 | 1951篇 |
外国民族医学 | 4篇 |
外科学 | 8770篇 |
综合类 | 375篇 |
一般理论 | 35篇 |
预防医学 | 4099篇 |
眼科学 | 804篇 |
药学 | 3653篇 |
中国医学 | 154篇 |
肿瘤学 | 3561篇 |
出版年
2023年 | 206篇 |
2022年 | 414篇 |
2021年 | 966篇 |
2020年 | 704篇 |
2019年 | 1283篇 |
2018年 | 1472篇 |
2017年 | 1158篇 |
2016年 | 1236篇 |
2015年 | 1541篇 |
2014年 | 1947篇 |
2013年 | 2709篇 |
2012年 | 3555篇 |
2011年 | 3809篇 |
2010年 | 2411篇 |
2009年 | 2178篇 |
2008年 | 3455篇 |
2007年 | 3610篇 |
2006年 | 3455篇 |
2005年 | 3606篇 |
2004年 | 3461篇 |
2003年 | 3440篇 |
2002年 | 3397篇 |
2001年 | 737篇 |
2000年 | 617篇 |
1999年 | 728篇 |
1998年 | 769篇 |
1997年 | 681篇 |
1996年 | 549篇 |
1995年 | 592篇 |
1994年 | 478篇 |
1993年 | 465篇 |
1992年 | 437篇 |
1991年 | 413篇 |
1990年 | 359篇 |
1989年 | 346篇 |
1988年 | 314篇 |
1987年 | 338篇 |
1986年 | 321篇 |
1985年 | 275篇 |
1984年 | 297篇 |
1983年 | 254篇 |
1982年 | 293篇 |
1981年 | 266篇 |
1980年 | 251篇 |
1979年 | 197篇 |
1978年 | 164篇 |
1977年 | 171篇 |
1976年 | 122篇 |
1975年 | 128篇 |
1973年 | 128篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Schneider Ralph Dettmer Marius Peters Nora Lamdark Tenzin Luedi Markus M. Adamina Michel Doll Dietrich 《European Surgery》2022,54(2):117-125
European Surgery - Treatment of pilonidal sinus disease (PSD) requires a tailored approach. A national guideline was published in 2014. The current status of surgical PSD therapy... 相似文献
2.
Evelyne Harkemanne Jean‐Louis Dargent Pierre‐Paul Roquet‐Gravy Audrey Bulinckx 《Pediatric dermatology》2019,36(3):365-367
We report a case of benign lymphoplasmacytic plaque (LPP) in a child. These asymptomatic erythematous papulonodular lesions are an emerging clinicopathological entity. Herein, we describe a previously unreported site for LPP lesions, namely, the volar wrist and the distal ipsilateral palm. 相似文献
3.
Despite common experiences of identity damage, decline, and deterioration, many brain injury survivors succeed in reconstructing robust identities in the wake of injury. Yet, while this accomplishment greatly benefits survivors’ quality of life, little is known about how positive identity work might be facilitated or enhanced in therapeutic institutions. Drawing on data from a women’s self-help group, we argue that an egalitarian, reflective, strength-focused, and gender-segregated environment can provide female ABI (acquired brain injury) survivors with a fertile scene for identity enhancement and offer unique opportunities for collective identity development. Sociolinguistic interactional analysis revealed four types of positive identity work undertaken within the group: constructing competent selves; tempering the threat of loss and impairment; resisting infantilisation and delegitimisation; and asserting a collective gender identity. This identity work was facilitated by specific programme attributes and activities and contributed to the global project of decentring disability and destigmatising impairments and losses. We call for increased attention to identity issues in brain injury rehabilitation and argue that gender-segregated programming can provide a unique space for female survivors to construct empowering individual and collective identities after injury. 相似文献
4.
Jean‐Franois Etter 《Addiction (Abingdon, England)》2019,114(12):2252-2256
5.
6.
7.
8.
9.
PNPLA3 gene polymorphism and response to lifestyle modification in patients with nonalcoholic fatty liver disease 下载免费PDF全文
10.
Dominique Trudel Luminita-Mihaela Avarvarei Michèle Orain Stéphane Turcotte Marie Plante Jean Grégoire Reinhild Kappelhoff David P. Labbé Dimcho Bachvarov Bernard Têtu Christopher M. Overall Isabelle Bairati 《Pathology, research and practice》2019,215(6):152369
Ovarian carcinoma is one of the most lethal malignancies, but only very few prognostic biomarkers are known. The degradome, comprising proteases, protease non-proteolytic homologues and inhibitors, have been involved in the prognosis of many cancer types, including ovarian carcinoma. The prognostic significance of the whole degradome family has not been specifically studied in high-grade serous ovarian cancer. A targeted DNA microarray known as the CLIP-CHIP microarray was used to identify potential prognostic factors in ten high-grade serous ovarian cancer women who had early recurrence (<1.6 years) or late/no recurrence after first line surgery and chemotherapy. In women with early recurrence, we identified seven upregulated genes (TMPRSS4, MASP1/3, SPC18, PSMB1, IGFBP2, CFI – encoding Complement Factor I – and MMP9) and one down-regulated gene (ADAM-10). Using immunohistochemistry, we evaluated the prognostic effect of these 8 candidate genes in an independent cohort of 112 high-grade serous ovarian cancer women. Outcomes were progression, defined according to CA-125 criteria, and death. Multivariate Cox proportional hazard regression models were done to estimate the associations between each protein and each outcome. High ADAM-10 expression (intensity of 2–3) was associated with a lower risk of progression (adjusted hazard ratio (HR): 0.51; 95% confidence interval (CI): 0.29-0.87). High complement factor I expression (intensity 2–3) was associated with a higher risk of progression (adjusted HR: 2.30, 95% CI: 1.17–4.53) and death (adjusted HR: 3.42; 95% CI: 1.72–6.79). Overall, we identified the prognostic value of two proteases, ADAM-10 and complement factor I, for high-grade serous ovarian cancer which could have clinical significance. 相似文献