全文获取类型
收费全文 | 104208篇 |
免费 | 42199篇 |
国内免费 | 127篇 |
专业分类
耳鼻咽喉 | 1762篇 |
儿科学 | 5033篇 |
妇产科学 | 1105篇 |
基础医学 | 19073篇 |
口腔科学 | 5368篇 |
临床医学 | 15645篇 |
内科学 | 28398篇 |
皮肤病学 | 7996篇 |
神经病学 | 15954篇 |
特种医学 | 3038篇 |
外国民族医学 | 1篇 |
外科学 | 17663篇 |
综合类 | 242篇 |
一般理论 | 51篇 |
预防医学 | 6667篇 |
眼科学 | 1563篇 |
药学 | 7102篇 |
中国医学 | 1062篇 |
肿瘤学 | 8811篇 |
出版年
2023年 | 127篇 |
2022年 | 269篇 |
2021年 | 1747篇 |
2020年 | 5294篇 |
2019年 | 11260篇 |
2018年 | 10663篇 |
2017年 | 11826篇 |
2016年 | 12456篇 |
2015年 | 12419篇 |
2014年 | 12534篇 |
2013年 | 13462篇 |
2012年 | 5768篇 |
2011年 | 5901篇 |
2010年 | 9879篇 |
2009年 | 6226篇 |
2008年 | 3676篇 |
2007年 | 2641篇 |
2006年 | 2668篇 |
2005年 | 2499篇 |
2004年 | 2439篇 |
2003年 | 2467篇 |
2002年 | 2618篇 |
2001年 | 1014篇 |
2000年 | 885篇 |
1999年 | 540篇 |
1998年 | 413篇 |
1997年 | 379篇 |
1996年 | 303篇 |
1995年 | 340篇 |
1994年 | 285篇 |
1993年 | 264篇 |
1992年 | 193篇 |
1991年 | 200篇 |
1990年 | 176篇 |
1989年 | 144篇 |
1988年 | 155篇 |
1987年 | 158篇 |
1986年 | 145篇 |
1985年 | 138篇 |
1984年 | 153篇 |
1983年 | 120篇 |
1982年 | 176篇 |
1981年 | 174篇 |
1980年 | 155篇 |
1979年 | 97篇 |
1978年 | 103篇 |
1977年 | 93篇 |
1976年 | 74篇 |
1975年 | 64篇 |
1972年 | 67篇 |
排序方式: 共有10000条查询结果,搜索用时 10 毫秒
1.
Barouyr Baroudjian Dimitri Arangalage Stefania Cuzzubbo Baptiste Hervier Celeste Lebbé Gwenael Lorillon 《Expert review of anticancer therapy》2019,19(3):209-222
Introduction: Immune checkpoint inhibitors (ICI) are now a standard of care in the treatment of many cancers leading to durable responses in patients with metastatic disease. These agents are generally well tolerated but may lead to the occurrence of immune-related adverse events (irAEs). As any organ may be affected, clinicians should be aware of the broad range of clinical manifestations and symptoms and keep in mind that toxicities may occur late, at any point along a patient’s treatment course. Although the most common irAEs are rarely severe, some of them may be associated with great morbidity and even become life-threatening. The rate of occurrence, type and severity of irAEs may vary with the type of ICI; thus, grade 3 and 4 irAEs are reported in more than 55% of patients treated with the combination of ipilimumab 3 mg/kg and nivolumab 1 mg/kg.
Area covered: This review presents the management of irAEs resulting from checkpoint blockade, with a focus on rare irAEs.
Expert commentary: With the development of immuno-oncology and the expanding role of ICI, physicians have learnt to diagnose and treat most of the irAEs that can occur. This review provides an overview of current guidelines, previously published studies and our multidisciplinary team based practices. 相似文献
2.
3.
4.
5.
Hyun Jong Choi Jong Ho Moon Yun Nah Lee Hyun Su Kim Ji Su Ha Tae Hoon Lee Sang‐Woo Cha Young Deok Cho Sang‐Heum Park 《Digestive endoscopy》2015,27(7):772-775
Direct peroral cholangioscopy (POC) using an ultra‐slim upper endoscope is one modality of POC for intraductal endoscopic evaluation and treatment of the bile duct. Choledochoduodenostomy (CDS) is one modality of biliary bypass surgery that provides a new route to the bile duct. We carried out direct POC using an ultra‐slim upper endoscope without the use of accessories in 10 patients (four sump syndromes, three bile duct strictures and three intrahepatic duct stones) previously undergoing surgical CDS. Direct POC was successful in all patients. The use of an intraductal balloon catheter was required in one patient for advancement of the endoscope into the bile duct. Distal bile ducts with sump syndromes were cleared using baskets and water irrigation under direct POC. Cholangiocarcinoma was diagnosed in one patient with hilar bile duct stricture after cholangioscopic evaluation and a targeting forceps biopsy under direct POC. Intrahepatic duct stones were successfully extracted after intraductal fragmentation under direct POC. Oozing bleeding occurred during intraductal lithotripsy but stopped spontaneously. Direct POC using an ultra‐slim upper endoscope without the assistance of accessories can easily be carried out in patients undergoing CDS. 相似文献
6.
7.
Well‐being,health and fitness of children who use wheelchairs: Feasibility study protocol to develop child‐centred ‘keep‐fit’ exercise interventions 下载免费PDF全文
8.
Interprofessional collaboration and communication in nursing homes: a qualitative exploration of problems in medical care for nursing home residents – study protocol 下载免费PDF全文
9.
Juan D. Gonzalez‐Sanz 《Nursing philosophy》2020,21(4)
The current situation in which the humanities are disparaged affects all university disciplines, including nursing, in whose historical evolution the humanities have always been present in one form or another. Looking beyond this disrepute, this study proposes that nursing renew its attention to classical philosophy. Specifically, it invites a close reading of Xenophon's Anabasis and Plato's Meno, to get three related goals: to show how the use of ancient texts are very valuable tools for the philosophical initiation of nursing students and can help them reflect on their choice of nursing as a practical activity; to reflect on the problem of virtue and the nature of the good life; and to show how the interaction with ancient texts allows students to reflect on questions and issues of life, theirs and others, that are not open to investigation through a purely scientific method. Consequently, both Anabasis and Meno readings strengthen the intellectual relationship between philosophy and nursing, enabling the latter to delve deeper into the key questions of its own thought as a discipline. 相似文献