全文获取类型
收费全文 | 284篇 |
免费 | 51篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 15篇 |
儿科学 | 6篇 |
妇产科学 | 4篇 |
基础医学 | 26篇 |
口腔科学 | 10篇 |
临床医学 | 29篇 |
内科学 | 90篇 |
皮肤病学 | 7篇 |
神经病学 | 12篇 |
特种医学 | 14篇 |
外科学 | 32篇 |
综合类 | 10篇 |
预防医学 | 22篇 |
眼科学 | 1篇 |
药学 | 44篇 |
中国医学 | 1篇 |
肿瘤学 | 14篇 |
出版年
2022年 | 4篇 |
2019年 | 6篇 |
2018年 | 5篇 |
2017年 | 3篇 |
2016年 | 7篇 |
2014年 | 6篇 |
2013年 | 11篇 |
2012年 | 11篇 |
2011年 | 16篇 |
2010年 | 8篇 |
2009年 | 7篇 |
2008年 | 6篇 |
2007年 | 12篇 |
2006年 | 9篇 |
2005年 | 6篇 |
2004年 | 5篇 |
2003年 | 8篇 |
2002年 | 7篇 |
2001年 | 5篇 |
2000年 | 7篇 |
1998年 | 3篇 |
1996年 | 5篇 |
1995年 | 5篇 |
1994年 | 3篇 |
1993年 | 5篇 |
1992年 | 18篇 |
1991年 | 7篇 |
1990年 | 12篇 |
1989年 | 8篇 |
1988年 | 15篇 |
1987年 | 12篇 |
1986年 | 5篇 |
1985年 | 10篇 |
1984年 | 8篇 |
1983年 | 9篇 |
1982年 | 3篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1979年 | 6篇 |
1978年 | 3篇 |
1975年 | 3篇 |
1974年 | 4篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1970年 | 5篇 |
1968年 | 3篇 |
1967年 | 3篇 |
1966年 | 2篇 |
1938年 | 3篇 |
排序方式: 共有337条查询结果,搜索用时 15 毫秒
1.
2.
Granulocytic sarcoma (chloroma), a rare tumor usually associated with myelogenous leukemia, is capable of invading the meninges or brain parenchyma. Radiologic findings in a case of granulocytic sarcoma of the brain, as well as those in 11 previously reported cases of intracranial leukemic masses, are interpreted. On computed tomographic scans, the lesions can appear isodense or hyperdense, edema and necrosis are variable, and there is uniform enhancement following intravenous administration of contrast material. There may be some affinity for the posterior fossa. 相似文献
3.
Renal transplant obstruction by B cell lymphoproliferative disorder: case report and review of the literature 总被引:1,自引:0,他引:1
L J Gibel A Harford L R Yogel J Spiegel W Sterling K Tung 《The Journal of urology》1988,140(3):593-595
We report a case of renal transplant ureteral obstruction caused by a cyclosporine-associated B cell lymphoproliferative disorder. The interaction of cyclosporine with Epstein-Barr virus infections and the predisposition towards B cell lymphoproliferative disorders are reviewed. The characterization of these tumors by deoxyribonucleic acid hybridization studies and a review of the clinical experience treating these disorders also are presented. 相似文献
4.
5.
A representative sample of 1,367 employed men and women in Detroit responded to questions about drinking practices and symptoms of depression. After controlling for age, education, family income, marital status, medication use, fathers' drinking, and other variables, increased quantity of alcohol consumed per drinking occasion was associated with increased depression symptoms in the sober state among men and women. Depression symptoms may be one of a group of not fully identified drug after-effect disorders involving psychological functioning. 相似文献
6.
7.
Thomas C. Harford Douglas A. Parker Bridget F. Grant Deborah A. Dawson 《Alcoholism, clinical and experimental research》1992,16(2):146-148
This paper provides estimates of alcohol consumption and alcohol dependence among employed men and women in the United States. Data from the 1988 National Health Interview Survey indicate that the percentages of drinkers in white-collar occupations are higher than the percentages of drinkers in blue-collar occupations among both men and women; however, the men and women in blue-collar occupations who drink have a higher average daily consumption than drinkers in white-collar occupations. DSM-III-R criteria were used to classify respondents as alcohol-dependent. Consistent with an earlier survey of employed adults in Detroit, the prevalence of alcohol dependence is highest in certain blue-collar occupations (craftsmen, laborers, and service workers among men; machine operators, laborers, and service workers among women). Directions for further research on the occupational and drinking experiences of employed men and women are discussed. 相似文献
8.
S Kaptain W E Downey C Tang C Philpott D Haile D G Orloff J B Harford T A Rouault R D Klausner 《Proceedings of the National Academy of Sciences of the United States of America》1991,88(22):10109-10113
A clone for the iron-responsive element (IRE)-binding protein (IRE-BP) has been transfected and expressed in mouse fibroblasts. The IRE-BP gene product binds IREs with high affinity and specificity. Amino acid alignments reveal that the IRE-BP is 30% identical to mitochondrial aconitase. The 18 active site residues of mitochondrial aconitase are identical to those in the IRE-BP, suggesting that the IRE-BP may possess aconitase activity. After purification of native IRE-BP and immunoaffinity purification of transfected and expressed IRE-BP, we demonstrate that the purified IRE-BP has aconitase activity. 相似文献
9.
James Cleary Henry Ddungu Sandra R. Distelhorst Carla Ripamonti Gary M. Rodin Mohammad A. Bushnaq Joe N. Clegg-Lamptey Stephen R. Connor Msemo B. Diwani Alexandru Eniu Joe B. Harford Suresh Kumar M.R. Rajagopal Beti Thompson Julie R. Gralow Benjamin O. Anderson 《Breast (Edinburgh, Scotland)》2013,22(5):616-627
Many women diagnosed with breast cancer in low- and middle-income countries (LMICs) present with advanced-stage disease. While cure is not a realistic outcome, site-specific interventions, supportive care, and palliative care can achieve meaningful outcomes and improve quality of life.As part of the 5th Breast Health Global Initiative (BHGI) Global Summit, an expert international panel identified thirteen key resource recommendations for supportive and palliative care for metastatic breast cancer. The recommendations are presented in three resource-stratified tables: health system resource allocations, resource allocations for organ-based metastatic breast cancer, and resource allocations for palliative care. These tables illustrate how health systems can provide supportive and palliative care services for patients at a basic level of available resources, and incrementally add services as more resources become available.The health systems table includes health professional education, patient and family education, palliative care models, and diagnostic testing. The metastatic disease management table provides recommendations for supportive care for bone, brain, liver, lung, and skin metastases as well as bowel obstruction. The third table includes the palliative care recommendations: pain management, and psychosocial and spiritual aspects of care.The panel considered pain management a priority at a basic level of resource allocation and emphasized the need for morphine to be easily available in LMICs. Regular pain assessments and the proper use of pharmacologic and non-pharmacologic interventions are recommended. Basic-level resources for psychosocial and spiritual aspects of care include health professional and patient and family education, as well as patient support, including community-based peer support. 相似文献
10.
Thomas C. Harford Chiung M. Chen Tulshi D. Saha Sharon M. Smith W. June Ruan Bridget F. Grant 《Journal of psychiatric research》2013