全文获取类型
收费全文 | 516篇 |
免费 | 37篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 29篇 |
妇产科学 | 4篇 |
基础医学 | 52篇 |
口腔科学 | 7篇 |
临床医学 | 43篇 |
内科学 | 170篇 |
皮肤病学 | 5篇 |
神经病学 | 22篇 |
特种医学 | 86篇 |
外科学 | 46篇 |
综合类 | 8篇 |
预防医学 | 25篇 |
眼科学 | 6篇 |
药学 | 35篇 |
肿瘤学 | 21篇 |
出版年
2021年 | 2篇 |
2020年 | 3篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2017年 | 8篇 |
2016年 | 7篇 |
2015年 | 11篇 |
2014年 | 7篇 |
2013年 | 22篇 |
2012年 | 13篇 |
2011年 | 10篇 |
2010年 | 19篇 |
2009年 | 17篇 |
2008年 | 18篇 |
2007年 | 12篇 |
2006年 | 13篇 |
2005年 | 13篇 |
2004年 | 9篇 |
2003年 | 7篇 |
2002年 | 9篇 |
2001年 | 3篇 |
2000年 | 5篇 |
1999年 | 11篇 |
1998年 | 25篇 |
1997年 | 31篇 |
1996年 | 31篇 |
1995年 | 22篇 |
1994年 | 25篇 |
1993年 | 20篇 |
1992年 | 12篇 |
1991年 | 12篇 |
1990年 | 16篇 |
1989年 | 14篇 |
1988年 | 8篇 |
1987年 | 15篇 |
1986年 | 14篇 |
1985年 | 5篇 |
1984年 | 9篇 |
1983年 | 6篇 |
1982年 | 5篇 |
1981年 | 14篇 |
1980年 | 8篇 |
1979年 | 2篇 |
1978年 | 5篇 |
1977年 | 5篇 |
1976年 | 11篇 |
1975年 | 4篇 |
1974年 | 3篇 |
1973年 | 2篇 |
1970年 | 2篇 |
排序方式: 共有559条查询结果,搜索用时 15 毫秒
1.
2.
3.
Diminished effect of etidronate in vitamin D deficient osteopenic postmenopausal women 总被引:7,自引:0,他引:7
J. C. Koster W. H. L. Hackeng H. Mulder 《European journal of clinical pharmacology》1996,51(2):145-147
Objective: The effects of vitamin D deficiency in osteopenic postmenopausal women treated with intermittent cyclical etidronate have
been studied. Bone mass and biochemical parameters as bone markers were measured before and after one year of therapy with
intermittent cyclical etidronate.
Results:
In 30 patients without vitamin D deficiency, bone mass in the lumbal spine and femoral neck was significantly increased compared
to 28 vitamin D deficient patients. After cyclical intermittent etidronate therapy, serum osteocalcin and PTH were significantly
increased in the vitamin D deficient patients, whereas in non-vitamin D deficient patients they did not change.
Conclusion:
It is worthwhile measuring serum vitamin D before starting etidronate therapy and, in case of deficiency, to give vitamin
D.
Received: 6 April 1995/Accepted in revised form: 23 April 1996 相似文献
4.
5.
J D Oosting R H Derksen T M Hackeng M van Vliet K T Preissner B N Bouma P G de Groot 《Thrombosis and haemostasis》1991,66(6):666-671
The effect of sera and purified IgG isolated from plasma of 46 patients with systemic lupus erythematosus (SLE) and 9 healthy donors on the endothelial cell (EC) mediated protein C activation was investigated. Out of the 46 SLE sera used, 19 were antiphospholipid antibodies (aPL) positive. From 12 patients IgG was isolated, of which 6 contained aPL. EC were first incubated with IgG (7 mg/ml) or serum (1:1 diluted) for 1 h and then tested for their ability to promote protein C activation by thrombin, with the cells either in a monolayer or in a suspension. The normal range (mean of control values +/- 2 SD) of protein C activation was 80-120%. In contrast to others, we could not detect an inhibition of protein C activation by any of the patient IgG's or sera. The recently described cofactor for binding of antiphospholipid antibodies to phospholipids, beta 2-glycoprotein I, was purified and added to the purified IgG's. A combination of these two components did not inhibit the EC mediated protein C activation by thrombin. This study suggests that the inhibition of the protein C activation, mediated by EC, is not a general mechanism by which aPL related thrombosis can be explained. 相似文献
6.
7.
8.
9.
10.